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Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor

Oxidative medicine and cellular longevity, 2019, Vol.2019, p.1036907-15

2019

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Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

Nature cell biology, 2011-04, Vol.13 (4), p.434

2011

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Maximising the potential of AKT inhibitors as anti-cancer treatments

Pharmacology & therapeutics (Oxford), 2017-04, Vol.172, p.101-115

2017

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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex

Cancer discovery, 2015-11, Vol.5 (11), p.1194-1209

2015

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FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107209-107209, Article 107209

2024

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TGF‐β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

The FEBS journal, 2017-10, Vol.284 (20), p.3437-3454

2017

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GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner

Experimental cell research, 2023-12, Vol.433 (2), p.113824-113824, Article 113824

2023

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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

Biochemical journal, 2014-04, Vol.459 (2), p.275-287

2014

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Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment

Journal of colloid and interface science, 2024-07, Vol.665, p.477-490

2024

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Caspase control: protagonists of cancer cell apoptosis

Experimental oncology, 2012-10, Vol.34 (3), p.165

2012

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MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling

Aging (Albany, NY.), 2019-08, Vol.11 (16), p.6371-6384

2019

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Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

Nature immunology, 2013-02, Vol.14 (2), p.162

2013

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TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription

Nature communications, 2019-12, Vol.10 (1), p.5720-16, Article 5720

2019

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ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

Nature cell biology, 2015-05, Vol.17 (5), p.627

2015

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An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105259-105259, Article 105259

2023

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Deep sequencing identified miR-193b-3p as a positive regulator of autophagy targeting Akt3 in Ctenopharyngodon idella CIK cells during GCRV infection

Fish & shellfish immunology, 2024-06, Vol.149, p.109586-109586, Article 109586

2024

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Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

Nature communications, 2017-01, Vol.8 (1), p.13700-13, Article 13700

2017

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Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

Journal of cellular physiology, 2017-02, Vol.232 (2), p.346-354

2017

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GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

Advances in biological regulation, 2017-08, Vol.65, p.5-15

2017

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A stress response pathway regulates DNA damage through β2―adrenoreceptors and β―arrestin―1

Nature (London), 2011-08, Vol.477 (7364), p.349-353

2011

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A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases

Endocrinology (Philadelphia), 2022-03, Vol.163 (3), p.1

Pru, James K

2022

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E3 ubiquitin ligase casitas B-lineage lymphoma-b modulates T-cell anergic resistance via phosphoinositide 3-kinase signaling in patients with immune thrombocytopenia

Journal of thrombosis and haemostasis, 2024-04, Vol.22 (4), p.1202-1214

2024

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Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2–AKT–TGF-β Signaling Axis in Pancreatic Cancer

Gastroenterology (New York, N.Y. 1943), 2022-06, Vol.162 (7), p.2004-2017.e2

2022

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PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway

Blood, 2024-05, Vol.143 (19), p.1965

2024

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TRPV4 regulates matrix stiffness and TGFβ1‐induced epithelial‐mesenchymal transition

Journal of cellular and molecular medicine, 2019-02, Vol.23 (2), p.761-774

2019

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Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

Maximising the potential of AKT inhibitors as anti-cancer treatments

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex

FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation

TGF‐β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment

Caspase control: protagonists of cancer cell apoptosis

MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling

Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing

Deep sequencing identified miR-193b-3p as a positive regulator of autophagy targeting Akt3 in Ctenopharyngodon idella CIK cells during GCRV infection

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

A stress response pathway regulates DNA damage through β2―adrenoreceptors and β―arrestin―1

A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases

E3 ubiquitin ligase casitas B-lineage lymphoma-b modulates T-cell anergic resistance via phosphoinositide 3-kinase signaling in patients with immune thrombocytopenia

Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2–AKT–TGF-β Signaling Axis in Pancreatic Cancer

PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway

TRPV4 regulates matrix stiffness and TGFβ1‐induced epithelial‐mesenchymal transition

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