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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012198-e1012198

2024

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Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies

Journal of bioscience and bioengineering, 2024-08, Vol.138 (2), p.127-136

2024

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Enhanced susceptibility of pediatric airway epithelium to respiratory syncytial virus infection

The Journal of clinical investigation, 2024-11, Vol.134 (21)

2024

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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Nature communications, 2015-09, Vol.6 (1), p.8143-8143, Article 8143

2015

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Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature communications, 2019-10, Vol.10 (1), p.4595-18

2019

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Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

PloS one, 2014, Vol.9 (6), p.e100392

2014

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The race to make vaccines for a dangerous respiratory virus

Nature (London), 2021-12, Vol.600 (7889), p.379-380

Powell, Kendall

2021

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Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

Nature (London), 2013-09, Vol.501 (7467), p.439-443

2013

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A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

Nature communications, 2016-12, Vol.7 (1), p.13916-12, Article 13916

2016

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Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation

Science (American Association for the Advancement of Science), 2024-09, Vol.385 (6716), p.1484-1491

2024

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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

Nature communications, 2018-05, Vol.9 (1), p.1904-10, Article 1904

2018

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Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting

PloS one, 2015-09, Vol.10 (9), p.e0138018-e0138018

2015

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Long-term efficacy and immunogenicity of Ad26.RSV.preF–RSV preF protein vaccine (CYPRESS): a randomised, double-blind, placebo-controlled, phase 2b study

The Lancet infectious diseases, 2024-09, Vol.24 (9), p.1015-1024

2024

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Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B

PloS one, 2017-04, Vol.12 (4), p.e0175792-e0175792

2017

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A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models

PloS one, 2015-03, Vol.10 (3), p.e0119509-e0119509

2015

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Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20822-20827

2008

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Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves

Scientific reports, 2019-10, Vol.9 (1), p.15157-14, Article 15157

2019

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Safety and immunogenicity of a live attenuated RSV vaccine in healthy RSV-seronegative children 5 to 24 months of age

PloS one, 2013, Vol.8 (10), p.e77104

2013

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RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

Nature communications, 2015-12, Vol.6 (1), p.10224, Article 10224

2015

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Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine

PloS one, 2018-06, Vol.13 (6), p.e0199452-e0199452

2018

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Development of surface engineered antigenic exosomes as vaccines for respiratory syncytial virus

Scientific reports, 2021-11, Vol.11 (1), p.21358-21358, Article 21358

2021

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Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Antiviral research, 2019-08, Vol.168, p.9-17

2019

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Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6136), p.1113-1117

2013

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Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

Scientific reports, 2017-02, Vol.7 (1), p.42428-42428, Article 42428

2017

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Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice

PloS one, 2012-05, Vol.7 (5), p.e36812-e36812

2012

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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies

Enhanced susceptibility of pediatric airway epithelium to respiratory syncytial virus infection

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

The race to make vaccines for a dangerous respiratory virus

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting

Long-term efficacy and immunogenicity of Ad26.RSV.preF–RSV preF protein vaccine (CYPRESS): a randomised, double-blind, placebo-controlled, phase 2b study

Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B

A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models

Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG

Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves

Safety and immunogenicity of a live attenuated RSV vaccine in healthy RSV-seronegative children 5 to 24 months of age

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine

Development of surface engineered antigenic exosomes as vaccines for respiratory syncytial virus

Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model

Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice

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