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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012198-e1012198

2024

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Cold-adapted influenza vaccine carrying three repeats of a respiratory syncytial virus (RSV) fusion glycoprotein epitope site protects BALB/c mice and cotton rats against RSV infection

Antiviral research, 2024-09, Vol.229, p.105960, Article 105960

2024

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Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

Virology (New York, N.Y.), 2024-10, Vol.598, p.110194, Article 110194

2024

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The tricky second album: Licensure of an mRNA vaccine for respiratory syncytial virus

Molecular therapy, 2024-08, Vol.32 (8), p.2428-2428

Tregoning, John S.

2024

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Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections

Science translational medicine, 2015-08, Vol.7 (300), p.300ra127

2015

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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Nature communications, 2015-09, Vol.6 (1), p.8143-8143, Article 8143

2015

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Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection

Journal of virology, 2014-04, Vol.88 (8), p.4237-4250

2014

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Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

Immunity (Cambridge, Mass.), 2019-09, Vol.51 (3), p.429-442

2019

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Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Vaccine, 2016-09, Vol.34 (42), p.5114-5124

2016

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Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy

The New England journal of medicine, 2022-04, Vol.386 (17), p.1615-1626

2022

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Respiratory syncytial virus infection and novel interventions

Nature reviews. Microbiology, 2023-11, Vol.21 (11), p.734-749

2023

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Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

PloS one, 2014, Vol.9 (6), p.e100392

2014

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Immunology of bovine respiratory syncytial virus in calves

Molecular immunology, 2015-07, Vol.66 (1), p.48-56

2015

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The race to make vaccines for a dangerous respiratory virus

Nature (London), 2021-12, Vol.600 (7889), p.379-380

Powell, Kendall

2021

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Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

Journal of general virology, 2014-06, Vol.95 (Pt 6), p.1244-1254

2014

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Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature communications, 2019-10, Vol.10 (1), p.4595-18

2019

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Novel antigens for RSV vaccines

Current opinion in immunology, 2015-08, Vol.35, p.30-38

2015

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Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease

Clinical and vaccine immunology, 2016-03, Vol.23 (3), p.189-195

2016

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Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults

Science translational medicine, 2015-08, Vol.7 (300), p.300ra126

2015

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Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

The Journal of infectious diseases, 2020-06, Vol.221 (12), p.2050-2059

2020

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The role of Th17 and Treg responses in the pathogenesis of RSV infection

Pediatric research, 2015-11, Vol.78 (5), p.483-491

2015

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Long-Term SARS-CoV-2 Findings Related to Persisting Viral Antigen and Inflammation Resemble Those Reported for Influenza Virus and Respiratory Syncytial Virus

Viruses, 2024-08, Vol.16 (9), p.1353

Roberts, Jr, Norbert J

2024

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Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

Immunological reviews, 2011-01, Vol.239 (1), p.149-166

Graham, Barney S.

2011

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A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

Nature communications, 2016-12, Vol.7 (1), p.13916-12, Article 13916

2016

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An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

The Journal of infectious diseases, 2017-12, Vol.216 (11), p.1362-1370

2017

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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

Cold-adapted influenza vaccine carrying three repeats of a respiratory syncytial virus (RSV) fusion glycoprotein epitope site protects BALB/c mice and cotton rats against RSV infection

Mucosal delivery of a prefusogenic-F, glycoprotein, and matrix proteins-based virus-like particle respiratory syncytial virus vaccine induces protective immunity as evidenced by challenge studies in mice

The tricky second album: Licensure of an mRNA vaccine for respiratory syncytial virus

Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection

Immunological Lessons from Respiratory Syncytial Virus Vaccine Development

Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy

Respiratory syncytial virus infection and novel interventions

Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

Immunology of bovine respiratory syncytial virus in calves

The race to make vaccines for a dangerous respiratory virus

Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Novel antigens for RSV vaccines

Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease

Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults

Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

The role of Th17 and Treg responses in the pathogenesis of RSV infection

Long-Term SARS-CoV-2 Findings Related to Persisting Viral Antigen and Inflammation Resemble Those Reported for Influenza Virus and Respiratory Syncytial Virus

Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

An Adjuvanted, Postfusion F Protein–Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults

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