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GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma

Acta pharmacologica Sinica, 2024-09, Vol.45 (9), p.1937-1950

2024

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A novel small-molecular CCR5 antagonist promotes neural repair after stroke

Acta pharmacologica Sinica, 2023-10, Vol.44 (10), p.1935-1947

2023

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An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways

Acta pharmacologica Sinica, 2021-01, Vol.42 (1), p.36-44

2021

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Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery

Acta pharmacologica Sinica, 2020-01, Vol.41 (1), p.119-128

2020

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Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro

Acta pharmacologica Sinica, 2019-09, Vol.40 (9), p.1237-1244

2019

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Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis

Acta pharmacologica Sinica, 2021-07, Vol.42 (7), p.1180-1189

2021

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Inhibition of RAS function through targeting an allosteric regulatory site

Nature chemical biology, 2017-01, Vol.13 (1), p.62-68

2017

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Response prediction biomarkers and drug combinations of PARP inhibitors in prostate cancer

Acta pharmacologica Sinica, 2021-12, Vol.42 (12), p.1970-1980

2021

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Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway

Acta pharmacologica Sinica, 2019-07, Vol.40 (7), p.919-928

2019

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Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

Acta pharmacologica Sinica, 2021-05, Vol.42 (5), p.801-813

2021

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Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction

Acta pharmacologica Sinica, 2022-06, Vol.43 (6), p.1594-1604

2022

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Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle

Acta pharmacologica Sinica, 2022-01, Vol.43 (1), p.194-208

2022

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Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis

Acta pharmacologica Sinica, 2022-11, Vol.43 (11), p.2977-2992

2022

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Fluopsin C induces oncosis of human breast adenocarcinoma cells

Acta pharmacologica Sinica, 2013-08, Vol.34 (8), p.1093-1100

2013

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PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis

Acta pharmacologica Sinica, 2023-02, Vol.44 (2), p.454-464

2023

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ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway

Acta pharmacologica Sinica, 2022-10, Vol.43 (10), p.2709-2722

2022

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An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases

Acta pharmacologica Sinica, 2015-11, Vol.36 (11), p.1337-1348

2015

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Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation

Acta pharmacologica Sinica, 2015-05, Vol.36 (5), p.565-571

2015

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Assessment of myocardial blood perfusion improved by CD151 in a pig myocardial infarction model

Acta pharmacologica Sinica, 2009-01, Vol.30 (1), p.70-77

2009

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Novel CDK9 inhibitor oroxylin A promotes wild-type P53 stability and prevents hepatocellular carcinoma progression by disrupting both MDM2 and SIRT1 signaling

Acta pharmacologica Sinica, 2022-04, Vol.43 (4), p.1033-1045

2022

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S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis

Acta pharmacologica Sinica, 2022-03, Vol.43 (3), p.602-612

2022

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Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro

Acta pharmacologica Sinica, 2016-07, Vol.37 (7), p.941-949

2016

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Advances in the study of berberine and its derivatives： a focus on anti-inflammatory and anti- tumor effects in the digestive system

Acta pharmacologica Sinica, 2017-02, Vol.38 (2), p.157-167

2017

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Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury

Acta pharmacologica Sinica, 2022-03, Vol.43 (3), p.520-528

2022

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Channelopathies and drug discovery in the postgenomic era

Acta pharmacologica Sinica, 2011-06, Vol.32 (6), p.673-674

2011

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GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma

A novel small-molecular CCR5 antagonist promotes neural repair after stroke

An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways

Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery

Eukaryotic elongation factor-2 kinase regulates the cross-talk between autophagy and pyroptosis in doxorubicin-treated human melanoma cells in vitro

Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis

Inhibition of RAS function through targeting an allosteric regulatory site

Response prediction biomarkers and drug combinations of PARP inhibitors in prostate cancer

Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway

Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction

Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle

Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis

Fluopsin C induces oncosis of human breast adenocarcinoma cells

PPAR-γ alleviates the inflammatory response in TNF-α-induced fibroblast-like synoviocytes by binding to p53 in rheumatoid arthritis

ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway

An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases

Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation

Assessment of myocardial blood perfusion improved by CD151 in a pig myocardial infarction model

Novel CDK9 inhibitor oroxylin A promotes wild-type P53 stability and prevents hepatocellular carcinoma progression by disrupting both MDM2 and SIRT1 signaling

S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis

Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro

Advances in the study of berberine and its derivatives： a focus on anti-inflammatory and anti- tumor effects in the digestive system

Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury

Channelopathies and drug discovery in the postgenomic era

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