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Pancreatic lipase immobilization on cellulose filter paper for inhibitors screening and network pharmacology study of anti-obesity mechanism

Talanta (Oxford), 2024-12, Vol.280, p.126750, Article 126750

2024

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From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling

Journal of the American Chemical Society, 2024-09, Vol.146 (36), p.24729-24741

2024

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Seeing through the Haze: Monoacylglycerol Lipase Inhibitors As Analgesics

The Journal of pharmacology and experimental therapeutics, 2024-08, Vol.390 (3), p.288

Wilkerson, Jenny L

2024

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Discovery of Novel Non-nucleoside DOT1L R231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy

Journal of medicinal chemistry, 2024-09, Vol.67 (18), p.16248-16269

2024

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Clotrimazole Identified as a Selective UGT2B4 Inhibitor Using Canagliflozin-2'- O -Glucuronide Formation as a Selective UGT2B4 Probe Reaction

Drug metabolism and disposition, 2024-09, Vol.52 (10), p.1083

2024

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Identification of a Polypeptide Inhibitor of O‑GlcNAc Transferase with Picomolar Affinity

Journal of the American Chemical Society, 2024-09, Vol.146 (38), p.26320-26330

2024

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Mechanism-Based Allylic Carbasugar Chlorides That Form Covalent Intermediates with α- and β-Galactosidases

Molecules (Basel, Switzerland), 2024-10, Vol.29 (20), p.4870

2024

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Design, Synthesis, and Biological Activity Evaluation of Eco-Friendly Rosin-Diamide-Based Fungicides as Potential Succinate Dehydrogenase Inhibitors for Sustainable Crop Protection

Journal of agricultural and food chemistry, 2024-10, Vol.72 (42), p.23131-23140

2024

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N-substituted-4-(pyridin-4-ylalkyl)piperazine-1-carboxamides and related compounds as Leishmania CYP51 and CYP5122A1 inhibitors

Bioorganic & medicinal chemistry, 2024-11, Vol.113, p.117907, Article 117907

2024

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Design and Synthesis of Novel Indole-Derived N‑Methylcarbamoylguanidinyl Chitinase Inhibitors with Significantly Improved Insecticidal Activity

Journal of agricultural and food chemistry, 2024-10, Vol.72 (39), p.21410-21418

2024

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Design and Synthesis of 3‑Carene-Derived Amide-Thiourea/Nanochitosan Complexes with Excellent Laccase Inhibitory Activity and Sustained Releasing Performance for Crop Protection

Journal of agricultural and food chemistry, 2024-10, Vol.72 (39), p.21429-21439

2024

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Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease

European journal of medicinal chemistry, 2024-12, Vol.279, p.116886, Article 116886

2024

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Regulation of protein phosphorylation by PTPN2 and its small-molecule inhibitors/degraders as a potential disease treatment strategy

European journal of medicinal chemistry, 2024-11, Vol.277, p.116774, Article 116774

2024

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Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors

PloS one, 2024-08, Vol.19 (8), p.e0306124

2024

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Defatted Wheat Germ Protein-Derived Peptides Showed Multiple Biological Activities from the Stomach to Small Intestine: In Silico and In Vitro Approaches

Journal of agricultural and food chemistry, 2024-09, Vol.72 (37), p.20527-20536

2024

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Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.14649-14667

2024

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A patent review of SCF E3 ligases inhibitors for cancer：Structural design, pharmacological activities and structure–activity relationship

European journal of medicinal chemistry, 2024-11, Vol.278, p.116821, Article 116821

2024

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Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review

European journal of pharmacology, 2024-10, Vol.981, p.176904, Article 176904

2024

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Synthesis, Urease Inhibition, Molecular Docking, and Optical Analysis of a Symmetrical Schiff Base and Its Selected Metal Complexes

Molecules (Basel, Switzerland), 2024-10, Vol.29 (20), p.4899

2024

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Enzyme Inhibitors as Multifaceted Tools in Medicine and Agriculture

Molecules (Basel, Switzerland), 2024-09, Vol.29 (18), p.4314

2024

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Development of an Ultrasensitive Competitive Double-Enzyme Cascade Fluorescence Signal Amplification Method for Factor XIa Inhibitor Screening

Analytical chemistry (Washington), 2024-10, Vol.96 (40), p.16091-16098

2024

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Accelerated molecular dynamics study of the interaction mechanism between small molecule inhibitors and phosphoglycerate mutase 1

Physical chemistry chemical physics : PCCP, 2024-10, Vol.26 (42), p.26784-26798

2024

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Citrus-derived flavanones as neuraminidase inhibitors: In vitro and in silico study

European journal of medicinal chemistry, 2024-11, Vol.277, p.116758, Article 116758

2024

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Fast Screening of Tyrosinase Inhibitors in Coreopsis tinctoria Nutt. by Ligand Fishing Based on Paper-Immobilized Tyrosinase

Molecules (Basel, Switzerland), 2024-08, Vol.29 (17), p.4018

2024

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New Phytol Derivatives with Increased Cosmeceutical Potential

Molecules (Basel, Switzerland), 2024-10, Vol.29 (20), p.4917

2024

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Pancreatic lipase immobilization on cellulose filter paper for inhibitors screening and network pharmacology study of anti-obesity mechanism

From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling

Seeing through the Haze: Monoacylglycerol Lipase Inhibitors As Analgesics

Discovery of Novel Non-nucleoside DOT1L R231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy

Clotrimazole Identified as a Selective UGT2B4 Inhibitor Using Canagliflozin-2'- O -Glucuronide Formation as a Selective UGT2B4 Probe Reaction

Identification of a Polypeptide Inhibitor of O‑GlcNAc Transferase with Picomolar Affinity

Mechanism-Based Allylic Carbasugar Chlorides That Form Covalent Intermediates with α- and β-Galactosidases

Design, Synthesis, and Biological Activity Evaluation of Eco-Friendly Rosin-Diamide-Based Fungicides as Potential Succinate Dehydrogenase Inhibitors for Sustainable Crop Protection

N-substituted-4-(pyridin-4-ylalkyl)piperazine-1-carboxamides and related compounds as Leishmania CYP51 and CYP5122A1 inhibitors

Design and Synthesis of Novel Indole-Derived N‑Methylcarbamoylguanidinyl Chitinase Inhibitors with Significantly Improved Insecticidal Activity

Design and Synthesis of 3‑Carene-Derived Amide-Thiourea/Nanochitosan Complexes with Excellent Laccase Inhibitory Activity and Sustained Releasing Performance for Crop Protection

Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease

Regulation of protein phosphorylation by PTPN2 and its small-molecule inhibitors/degraders as a potential disease treatment strategy

Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors

Defatted Wheat Germ Protein-Derived Peptides Showed Multiple Biological Activities from the Stomach to Small Intestine: In Silico and In Vitro Approaches

Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform

A patent review of SCF E3 ligases inhibitors for cancer：Structural design, pharmacological activities and structure–activity relationship

Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review

Synthesis, Urease Inhibition, Molecular Docking, and Optical Analysis of a Symmetrical Schiff Base and Its Selected Metal Complexes

Enzyme Inhibitors as Multifaceted Tools in Medicine and Agriculture

Development of an Ultrasensitive Competitive Double-Enzyme Cascade Fluorescence Signal Amplification Method for Factor XIa Inhibitor Screening

Accelerated molecular dynamics study of the interaction mechanism between small molecule inhibitors and phosphoglycerate mutase 1

Citrus-derived flavanones as neuraminidase inhibitors: In vitro and in silico study

Fast Screening of Tyrosinase Inhibitors in Coreopsis tinctoria Nutt. by Ligand Fishing Based on Paper-Immobilized Tyrosinase

New Phytol Derivatives with Increased Cosmeceutical Potential

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