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The curious case of benzbromarone: insight into super-inhibition of cytochrome P450

PloS one, 2014-03, Vol.9 (3), p.e89967-e89967

2014

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Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells

PloS one, 2015-03, Vol.10 (3), p.e0118943-e0118943

2015

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A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors

PloS one, 2024-06, Vol.19 (6), p.e0305000

2024

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Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation

PloS one, 2014-01, Vol.9 (1), p.e86365-e86365

2014

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Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations

PloS one, 2020-05, Vol.15 (5), p.e0233468

2020

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Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors

PloS one, 2024-08, Vol.19 (8), p.e0306124

2024

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A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts

PloS one, 2014-06, Vol.9 (6), p.e100993

2014

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Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway

PloS one, 2012-12, Vol.7 (12), p.e51655-e51655

2012

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Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

PloS one, 2015-07, Vol.10 (7), p.e0132367-e0132367

2015

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Systematic review and meta-analysis of the clinical outcomes of ACEI/ARB in East-Asian patients with COVID-19

PloS one, 2023-01, Vol.18 (1), p.e0280280

2023

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Identification, structure-activity relationship and in silico molecular docking analyses of five novel angiotensin I-converting enzyme (ACE)-inhibitory peptides from stone fish (Actinopyga lecanora) hydrolysates

PloS one, 2019-05, Vol.14 (5), p.e0197644-e0197644

2019

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Discovery of novel allosteric effectors based on the predicted allosteric sites for Escherichia coli D-3-phosphoglycerate dehydrogenase

PloS one, 2014-04, Vol.9 (4), p.e94829-e94829

2014

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Aqueous extract of Peristrophe bivalvis (L.) Merr. leaf reversed the detrimental effects of nitric oxide synthase inhibitor on blood lipid profile and glucose level

PloS one, 2024-09, Vol.19 (9), p.e0308338

2024

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Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase

PloS one, 2014-09, Vol.9 (9), p.e106039

2014

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Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers

PloS one, 2013-09, Vol.8 (9), p.e75184-e75184

2013

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Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production

PloS one, 2016-09, Vol.11 (9), p.e0162497

2016

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Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties

PloS one, 2015-05, Vol.10 (5), p.e0124481-e0124481

2015

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Timing matters in the use of renin-angiotensin system modulators and COVID-related cognitive and cerebrovascular dysfunction

PloS one, 2024-07, Vol.19 (7), p.e0304135

2024

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MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma

PloS one, 2013-01, Vol.8 (1), p.e53906

2013

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Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells

PloS one, 2015-09, Vol.10 (9), p.e0133813-e0133813

2015

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The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

PloS one, 2020-07, Vol.15 (7), p.e0235705

2020

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Theory on the rate equations of Michaelis-Menten type enzyme kinetics with competitive inhibition

PloS one, 2024-07, Vol.19 (7), p.e0302679

2024

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Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

The curious case of benzbromarone: insight into super-inhibition of cytochrome P450

Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors

Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation

Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations

Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors

A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts

Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway

Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo

Systematic review and meta-analysis of the clinical outcomes of ACEI/ARB in East-Asian patients with COVID-19

Identification, structure-activity relationship and in silico molecular docking analyses of five novel angiotensin I-converting enzyme (ACE)-inhibitory peptides from stone fish (Actinopyga lecanora) hydrolysates

Discovery of novel allosteric effectors based on the predicted allosteric sites for Escherichia coli D-3-phosphoglycerate dehydrogenase

Aqueous extract of Peristrophe bivalvis (L.) Merr. leaf reversed the detrimental effects of nitric oxide synthase inhibitor on blood lipid profile and glucose level

Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers

Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production

Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties

Timing matters in the use of renin-angiotensin system modulators and COVID-related cognitive and cerebrovascular dysfunction

MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma

Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

Theory on the rate equations of Michaelis-Menten type enzyme kinetics with competitive inhibition

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