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Nuclear lamins and laminopathies

The Journal of pathology, 2012-01, Vol.226 (2), p.316-325

Worman, Howard J.

2012

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Nuclear Positioning

Cell, 2013-03, Vol.152 (6), p.1376-1389

2013

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Molecular Pathology of Laminopathies

Annual review of pathology, 2022-01, Vol.17 (1), p.159-180

2022

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Accessorizing and anchoring the LINC complex for multifunctionality

The Journal of cell biology, 2015-01, Vol.208 (1), p.11-22

2015

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Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization

PLoS genetics, 2014-09, Vol.10 (9), p.e1004605-e1004605

2014

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The Nuclear Envelope as a Signaling Node in Development and Disease

Developmental cell, 2009-11, Vol.17 (5), p.626-638

2009

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Prelamin A and ZMPSTE24 in premature and physiological aging

Nucleus (Austin, Tex.), 2023-12, Vol.14 (1), p.2270345-2270345

2023

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Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Circulation (New York, N.Y.), 2011-01, Vol.123 (1), p.53-61

2011

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Laminopathies and the long strange trip from basic cell biology to therapy

The Journal of clinical investigation, 2009-07, Vol.119 (7), p.1825-1836

2009

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ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Human molecular genetics, 2016-06, Vol.25 (11), p.2220-2233

2016

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Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

Science translational medicine, 2012-07, Vol.4 (144), p.144ra102

2012

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Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

Human molecular genetics, 2020-12, Vol.29 (24), p.3919-3934

2020

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Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts

Molecular biology of the cell, 2013-12, Vol.24 (24), p.3869-3880

2013

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Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets

Journal of lipid research, 2022-10, Vol.63 (10), p.100277-100277, Article 100277

2022

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Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation

Human molecular genetics, 2018-09, Vol.27 (17), p.3060-3078

2018

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Extracellular matrix remodeling and transforming growth factor-β signaling abnormalities induced by lamin A/C variants that cause lipodystrophy

Journal of lipid research, 2017-01, Vol.58 (1), p.151-163

2017

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Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (1), p.131-136

2011

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TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement

The Journal of cell biology, 2017-03, Vol.216 (3), p.657-674

2017

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Biliary apotopes and anti‐mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

Hepatology (Baltimore, Md.), 2010-09, Vol.52 (3), p.987-998

2010

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Risk factors and comorbidities in primary biliary cirrhosis : A controlled interview-based study of 1032 patients

Hepatology (Baltimore, Md.), 2005-11, Vol.42 (5), p.1194-1202

2005

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Apoptosis-induced translocation of nesprin-2 from the nuclear envelope to mitochondria is associated with mitochondrial dysfunction

Nucleus (Austin, Tex.), 2024-12, Vol.15 (1), p.2413501

2024

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Lamina-Associated Polypeptide-1 Interacts with the Muscular Dystrophy Protein Emerin and Is Essential for Skeletal Muscle Maintenance

Developmental cell, 2013-09, Vol.26 (6), p.591-603

2013

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Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Human molecular genetics, 2018-07, Vol.27 (13), p.2290-2305

2018

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Reactivation of autophagy ameliorates LMNA cardiomyopathy

Autophagy, 2013-01, Vol.9 (1), p.110-111

2013

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Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

The Journal of clinical investigation, 2007-05, Vol.117 (5), p.1282-1293

2007

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Nuclear lamins and laminopathies

Nuclear Positioning

Molecular Pathology of Laminopathies

Accessorizing and anchoring the LINC complex for multifunctionality

Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization

The Nuclear Envelope as a Signaling Node in Development and Disease

Prelamin A and ZMPSTE24 in premature and physiological aging

Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

Laminopathies and the long strange trip from basic cell biology to therapy

ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts

Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets

Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation

Extracellular matrix remodeling and transforming growth factor-β signaling abnormalities induced by lamin A/C variants that cause lipodystrophy

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement

Biliary apotopes and anti‐mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

Risk factors and comorbidities in primary biliary cirrhosis : A controlled interview-based study of 1032 patients

Apoptosis-induced translocation of nesprin-2 from the nuclear envelope to mitochondria is associated with mitochondrial dysfunction

Lamina-Associated Polypeptide-1 Interacts with the Muscular Dystrophy Protein Emerin and Is Essential for Skeletal Muscle Maintenance

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Reactivation of autophagy ameliorates LMNA cardiomyopathy

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

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