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Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

1, 2016

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Evaluation of multiple prediction models: A novel view on model selection and performance assessment

Statistical methods in medical research, 2020-06, Vol.29 (6), p.1728-1745

2020

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Simultaneous confidence intervals for an extended Koch-Röhmel design in three-arm non-inferiority trials

Statistical methods in medical research, 2023-09, Vol.32 (9), p.1784-1798

2023

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A graphical approach to sequentially rejective multiple test procedures

Statistics in medicine, 2009-02, Vol.28 (4), p.586-604

2009

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The population-wise error rate for clinical trials with overlapping populations

Statistical methods in medical research, 2023-02, Vol.32 (2), p.334-352

2023

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Blinded sample size re-estimation in a comparative diagnostic accuracy study

BMC medical research methodology, 2022-04, Vol.22 (1), p.115-115, Article 115

2022

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Adaptive designs for confirmatory clinical trials

Statistics in medicine, 2009-04, Vol.28 (8), p.1181-1217

2009

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Interval and point estimation in adaptive Phase II trials with binary endpoint

Statistical methods in medical research, 2019-09, Vol.28 (9), p.2635-2648

2019

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Discussion on “Optimal test procedures for multiple hypotheses controlling the familywise expected loss” by Willi Maurer, Frank Bretz, and Xiaolei Xun

Biometrics, 2023-12, Vol.79 (4), p.2806-2810

Brannath, Werner

2023

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Testing multiple dose combinations in clinical trials

Statistical methods in medical research, 2020-07, Vol.29 (7), p.1799-1817

2020

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A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

Statistical methods in medical research, 2019-08, Vol.28 (8), p.2538-2556

2019

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Is there a role for statistics in artificial intelligence?

Advances in data analysis and classification, 2022-12, Vol.16 (4), p.823-846

2022

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Adaptive Dunnett tests for treatment selection

Statistics in medicine, 2008-05, Vol.27 (10), p.1612-1625

2008

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Opportunities and challenges of combined effect measures based on prioritized outcomes

Statistics in medicine, 2014-03, Vol.33 (7), p.1104-1120

2014

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Effectiveness of a peer-supported crisis intervention to reduce the proportion of compulsory admissions in acute psychiatric crisis interventions in an outreach and outpatient setting: study protocol for an exploratory cluster randomised trial combined with qualitative methods

BMJ open, 2024-05, Vol.14 (5), p.e083385

2024

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Shortcuts for Locally Consonant Closed Test Procedures

Journal of the American Statistical Association, 2010-06, Vol.105 (490), p.660-669

2010

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Early use of acute medication for preventing migraine attacks: Results from a diary-based cohort study

Cephalalgia reports, 2020, Vol.3, p.251581632094492

2020

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Smartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E): study protocol for a multicentre pragmatic randomized controlled trial

BMC musculoskeletal disorders, 2023-03, Vol.24 (1), p.221-221, Article 221

2023

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Parameter Optimization in High-Throughput Testing for Structural Materials

Materials, 2019-10, Vol.12 (20), p.3439

2019

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Simultaneous confidence intervals for ratios with application to the gold standard design with more than one experimental treatment

Statistics in medicine, 2019-12, Vol.38 (28), p.5350-5360

2019

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Contribution to the discussion of “A critical evaluation of the current ‘p‐value controversy’”

Biometrical journal, 2017-09, Vol.59 (5), p.875-876

Brannath, Werner

2017

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Issues in designing flexible trials

Statistics in medicine, 2003-03, Vol.22 (6), p.953-969

2003

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Single‐stage, three‐arm, adaptive test strategies for non‐inferiority trials with an unstable reference

Statistics in medicine, 2022-11, Vol.41 (25), p.5033-5045

2022

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A multiple testing framework for diagnostic accuracy studies with co‐primary endpoints

Statistics in medicine, 2022-02, Vol.41 (5), p.891-909

2022

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Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

Evaluation of multiple prediction models: A novel view on model selection and performance assessment

Simultaneous confidence intervals for an extended Koch-Röhmel design in three-arm non-inferiority trials

A graphical approach to sequentially rejective multiple test procedures

The population-wise error rate for clinical trials with overlapping populations

Blinded sample size re-estimation in a comparative diagnostic accuracy study

Adaptive designs for confirmatory clinical trials

Interval and point estimation in adaptive Phase II trials with binary endpoint

Discussion on “Optimal test procedures for multiple hypotheses controlling the familywise expected loss” by Willi Maurer, Frank Bretz, and Xiaolei Xun

Testing multiple dose combinations in clinical trials

A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

Is there a role for statistics in artificial intelligence?

Adaptive Dunnett tests for treatment selection

Opportunities and challenges of combined effect measures based on prioritized outcomes

Effectiveness of a peer-supported crisis intervention to reduce the proportion of compulsory admissions in acute psychiatric crisis interventions in an outreach and outpatient setting: study protocol for an exploratory cluster randomised trial combined with qualitative methods

Shortcuts for Locally Consonant Closed Test Procedures

Early use of acute medication for preventing migraine attacks: Results from a diary-based cohort study

Smartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E): study protocol for a multicentre pragmatic randomized controlled trial

Effectiveness and costs of a low-threshold hearing screening programme (HörGeist) for individuals with intellectual disabilities: protocol for a screening study

Parameter Optimization in High-Throughput Testing for Structural Materials

Simultaneous confidence intervals for ratios with application to the gold standard design with more than one experimental treatment

Contribution to the discussion of “A critical evaluation of the current ‘p‐value controversy’”

Issues in designing flexible trials

Single‐stage, three‐arm, adaptive test strategies for non‐inferiority trials with an unstable reference

A multiple testing framework for diagnostic accuracy studies with co‐primary endpoints

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