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KRAS-Mutant Lung Cancer: Targeting Molecular and Immunologic Pathways, Therapeutic Advantages and Restrictions

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.749

2023

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Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

Cancers, 2022-03, Vol.14 (7), p.1785

2022

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Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

Molecular cancer, 2013-12, Vol.12 (1), p.154-154, Article 154

2013

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Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

Nature communications, 2018-11, Vol.9 (1), p.4589-11, Article 4589

2018

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Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Frontiers in oncology, 2020-01, Vol.9, p.1556-1556

2020

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Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10930

2022

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The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis

International journal of colorectal disease, 2007-09, Vol.22 (9), p.999-1003

2007

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Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras-mutant lung cancer

JCI insight, 2022-06, Vol.7 (11)

2022

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Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

Frontiers in immunology, 2023, Vol.14, p.1118721

2023

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Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer

International journal of chronic obstructive pulmonary disease, 2011, Vol.6 (default), p.113-123

2011

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OBIF: an omics-based interaction framework to reveal molecular drivers of synergy

NAR genomics and bioinformatics, 2022-06, Vol.4 (2)

2022

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1330 Gut microbiome dysbiosis promotes immune suppression and lung cancer development

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1481-A1481

2023

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Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

Molecular cancer, 2012-01, Vol.11 (1), p.4-4, Article 4

2012

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Lung Cancer Murine Models and Methodology for Immunopreventive Study

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2435, p.203

2022

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Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing

Cancer discovery, 2021-10, Vol.11 (10), p.2506-2523

2021

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Abstract A012: Repurposing of the macrolide antibiotic clarithromycin for the prevention of lung cancer

Cancer prevention research (Philadelphia, Pa.), 2022-12, Vol.15 (12_Supplement_2), p.A012-A012

2022

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Reduced IL‐6 levels and tumor‐associated phospho‐STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo‐inositol

International journal of cancer, 2018-04, Vol.142 (7), p.1405-1417

2018

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Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer

Carcinogenesis (New York), 2020-11, Vol.41 (11), p.1529-1542

2020

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STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13

Nature communications, 2014-12, Vol.5 (1), p.5798-5798, Article 5798

2014

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IL22 Promotes Kras -Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties

Cancer immunology research, 2018-07, Vol.6 (7), p.788-797

2018

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Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis

Lung cancer (Amsterdam, Netherlands), 2017-10, Vol.112, p.47-56

2017

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COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

Oncotarget, 2018-08, Vol.9 (68), p.32972-32983

2018

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Cigarette smoke exposure accelerates AML progression in FLT3-ITD models

Blood advances, 2023-11, Vol.7 (21), p.6624-6629

2023

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KRAS-Mutant Lung Cancer: Targeting Molecular and Immunologic Pathways, Therapeutic Advantages and Restrictions

Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes

The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis

Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras-mutant lung cancer

Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium

Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer

OBIF: an omics-based interaction framework to reveal molecular drivers of synergy

1330 Gut microbiome dysbiosis promotes immune suppression and lung cancer development

Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

Lung Cancer Murine Models and Methodology for Immunopreventive Study

Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing

Abstract A012: Repurposing of the macrolide antibiotic clarithromycin for the prevention of lung cancer

Reduced IL‐6 levels and tumor‐associated phospho‐STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo‐inositol

Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13

IL22 Promotes Kras -Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties

Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis

COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

Cigarette smoke exposure accelerates AML progression in FLT3-ITD models

Inflammation mediated by gut microbiome alterations promotes lung cancer development and an immunosuppressed tumor microenvironment

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