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Effect of Gambogenic Acid on Cytochrome P450 1A2, 2B1 and 2E1, and Constitutive Androstane Receptor in Rats

European journal of drug metabolism and pharmacokinetics, 2018-12, Vol.43 (6), p.655-664

2018

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Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

International journal of toxicology, 2014-07, Vol.33 (4), p.307-318

2014

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A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Pharmaceutical research, 2006-03, Vol.23 (3), p.521-532

2006

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Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Toxicological sciences, 2001-05, Vol.61 (1), p.76-82

2001

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CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers

Toxicology (Amsterdam), 2005-12, Vol.216 (2), p.147-153

2005

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The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Archives of biochemistry and biophysics, 2001-10, Vol.394 (1), p.21-28

2001

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Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Biochemical pharmacology, 2014-02, Vol.87 (4), p.636-649

2014

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Analysis of Species-Selectivity of Human, Mouse and Rat Cytochrome P450 1A and 2B Subfamily Enzymes using Molecular Modeling, Docking and Dynamics Simulations

Cell biochemistry and biophysics, 2018-06, Vol.76 (1-2), p.91-110

2018

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Higher gene expression of CYP1A2, 2B1 and 2D2 in the brain of female compared with male rats

Pharmazie, 2016-06, Vol.71 (6), p.334-336

2016

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A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Chemosphere (Oxford), 2008-09, Vol.73 (2), p.209-215

2008

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Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition Sites

The Journal of pharmacology and experimental therapeutics, 2004-10, Vol.311 (1), p.71-79

2004

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Role of Nitric Oxide in Down-Regulation of CYP2B1 Protein, but Not RNA, in Primary Cultures of Rat Hepatocytes

Molecular pharmacology, 2001-07, Vol.60 (1), p.209-216

2001

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Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Toxicological sciences, 2009-03, Vol.108 (1), p.69-80

2009

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Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Biochemical pharmacology, 2001-10, Vol.62 (8), p.1025-1036

2001

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Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Toxicology (Amsterdam), 2003-04, Vol.186 (1), p.67-77

2003

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Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain

Phytotherapy research, 2002-11, Vol.16 (7), p.639-645

2002

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Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

Archives of biochemistry and biophysics, 2002-03, Vol.399 (1), p.56-65

2002

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The effect of chronic kidney disease on CYP2B expression and activity in male Wistar rats

Pharmacology research & perspectives, 2019-06, Vol.7 (3), p.e00475-n/a

2019

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Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury

The Journal of nutrition, 2009-12, Vol.139 (12), p.2252-2256

2009

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Activation of the Anticancer Prodrugs Cyclophosphamide and Ifosfamide: Identification of Cytochrome P450 2B Enzymes and Site-Specific Mutants with Improved Enzyme Kinetics

Molecular pharmacology, 2004-05, Vol.65 (5), p.1278-1285

2004

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Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

European journal of medicinal chemistry, 2010-11, Vol.45 (11), p.4845-4855

2010

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Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Archives of biochemistry and biophysics, 2004-03, Vol.423 (2), p.277-287

2004

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Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

The Journal of Toxicological Sciences, 2011/04/01, Vol.36(2), pp.181-190

2011

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N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Toxicology letters, 2011-10, Vol.206 (2), p.139-143

2011

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Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells

Kidney international, 2010-07, Vol.78 (2), p.182-190

2010

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Effect of Gambogenic Acid on Cytochrome P450 1A2, 2B1 and 2E1, and Constitutive Androstane Receptor in Rats

Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers

The Role of Cytochrome 2B1 Substrate Recognition Site Residues 115, 294, 297, 298, and 362 in the Oxidation of Steroids and 7-Alkoxycoumarins

Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Analysis of Species-Selectivity of Human, Mouse and Rat Cytochrome P450 1A and 2B Subfamily Enzymes using Molecular Modeling, Docking and Dynamics Simulations

Higher gene expression of CYP1A2, 2B1 and 2D2 in the brain of female compared with male rats

A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition Sites

Role of Nitric Oxide in Down-Regulation of CYP2B1 Protein, but Not RNA, in Primary Cultures of Rat Hepatocytes

Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain

Toxicological Consequences of Differential Regulation of Cytochrome P450 Isoforms in Rat Brain Regions by Phenobarbital

The effect of chronic kidney disease on CYP2B expression and activity in male Wistar rats

Diallyl Trisulfide Protects Rats from Carbon Tetrachloride-Induced Liver Injury

Activation of the Anticancer Prodrugs Cyclophosphamide and Ifosfamide: Identification of Cytochrome P450 2B Enzymes and Site-Specific Mutants with Improved Enzyme Kinetics

Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells

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