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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

Chemistry & biodiversity, 2021-05, Vol.18 (5), p.e2001037-n/a

2021

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Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Cytometry. Part A, 2018-10, Vol.93 (10), p.1019-1028

2018

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Protein domain-based prediction of drug/compound-target interactions and experimental validation on LIM kinases

PLoS computational biology, 2021-11, Vol.17 (11), p.e1009171

2021

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The PI3K/AKT/mTOR interactive pathway

Molecular bioSystems, 2015-07, Vol.11 (7), p.1946-1954

2015

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Large‐scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants

Proteins, structure, function, and bioinformatics, 2018-02, Vol.86 (2), p.135-151

2018

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Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment

Molecular cancer therapeutics, 2019-11, Vol.18 (11), p.2146-2157

2019

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Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

Briefings in bioinformatics, 2019-09, Vol.20 (5), p.1878-1912

2019

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ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature

BMC bioinformatics, 2018-09, Vol.19 (1), p.334-334, Article 334

2018

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Synthesis and cytotoxicity of novel 6,8,9-trisubstituted purine analogs against liver cancer cells

Bioorganic & medicinal chemistry letters, 2024-07, Vol.106, p.129775-129775, Article 129775

2024

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Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics

European journal of medicinal chemistry, 2017-03, Vol.129, p.12-26

2017

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Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

BMC cancer, 2022-03, Vol.22 (1), p.320-17, Article 320

2022

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Synthesis of Novel 6-(4-Substituted piperazine-1-yl)-9-(β-d-ribofuranosyl)purine Derivatives, Which Lead to Senescence-Induced Cell Death in Liver Cancer Cells

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3058-3065

2012

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Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

eLife, 2020-04, Vol.9

2020

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Iterative h‐minima‐based marker‐controlled watershed for cell nucleus segmentation

Cytometry. Part A, 2016-04, Vol.89 (4), p.338-349

2016

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EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers

Oncogene, 2022-01, Vol.41 (2), p.220-232

2022

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PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

Molecular and cellular biology, 2015-05, Vol.35 (10), p.1741-1753

2015

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Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio)urea hybrids as potential kinase inhibitors

Computational biology and chemistry, 2019-02, Vol.78, p.227-241

2019

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Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors

Journal of molecular graphics & modelling, 2019-06, Vol.89, p.60-73

2019

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HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

eLife, 2022-07, Vol.11

2022

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Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

Frontiers in physiology, 2021-07, Vol.12, p.701995-701995

2021

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The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells

Archiv der Pharmazie (Weinheim), 2011-05, Vol.344 (5), p.333-339

2011

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Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

European journal of medicinal chemistry, 2021-10, Vol.221, p.113489-113489, Article 113489

2021

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Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

Industrial crops and products, 2018-11, Vol.124, p.389-396

2018

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iBioProVis: interactive visualization and analysis of compound bioactivity space

Bioinformatics, 2020-08, Vol.36 (14), p.4227-4230

2020

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Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1352-1361

2018

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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Protein domain-based prediction of drug/compound-target interactions and experimental validation on LIM kinases

The PI3K/AKT/mTOR interactive pathway

Large‐scale automated function prediction of protein sequences and an experimental case study validation on PTEN transcript variants

Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment

Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

ECPred: a tool for the prediction of the enzymatic functions of protein sequences based on the EC nomenclature

Synthesis and cytotoxicity of novel 6,8,9-trisubstituted purine analogs against liver cancer cells

Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics

Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

Synthesis of Novel 6-(4-Substituted piperazine-1-yl)-9-(β-d-ribofuranosyl)purine Derivatives, Which Lead to Senescence-Induced Cell Death in Liver Cancer Cells

Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

Iterative h‐minima‐based marker‐controlled watershed for cell nucleus segmentation

EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio)urea hybrids as potential kinase inhibitors

Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors

HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

iBioProVis: interactive visualization and analysis of compound bioactivity space

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

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