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Sodium channels in pain disorders: pathophysiology and prospects for treatment

Pain (Amsterdam), 2017-04, Vol.158 Suppl 1, p.S97

2017

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NaV1.7: A central role in pain

Neuron (Cambridge, Mass.), 2023-09, Vol.111 (17), p.2615-2617

2023

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Sodium channel genes in pain-related disorders: phenotype–genotype associations and recommendations for clinical use

Lancet neurology, 2014-11, Vol.13 (11), p.1152-1160

2014

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Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions

Neurobiology of disease, 2020-02, Vol.134, p.104708-104708, Article 104708

2020

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A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons

Experimental neurology, 2010-08, Vol.224 (2), p.362-368

2010

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Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy

Neurobiology of disease, 2014-07, Vol.67, p.180-190

2014

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Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain

Pain (Amsterdam), 1999-12, Vol.83 (3), p.591-600

1999

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FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels

Molecular and cellular neuroscience, 2009-09, Vol.42 (2), p.90-101

2009

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Recent advances for using human induced-pluripotent stem cells as pain-in-a-dish models of neuropathic pain

Experimental neurology, 2022-12, Vol.358, p.114223-114223, Article 114223

2022

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Mini-review - Sodium channels and beyond in peripheral nerve disease: Modulation by cytokines and their effector protein kinases

Neuroscience letters, 2021-01, Vol.741, p.135446-135446, Article 135446

2021

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Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus

Experimental neurology, 2014-03, Vol.253, p.174-179

2014

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Nav1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation

Experimental neurology, 2023-06, Vol.364, p.114393-114393, Article 114393

2023

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Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain

Pain (Amsterdam), 2008-09, Vol.139 (1), p.90

2008

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Diversity of composition and function of sodium channels in peripheral sensory neurons

Pain (Amsterdam), 2015-12, Vol.156 (12), p.2406

2015

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Human pain in a dish: Native DRG neurons and differentiated pluripotent stem cells

Pain (Amsterdam), 2014-09, Vol.155 (9), p.1681

Dib-Hajj, Sulayman D

2014

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Factors associated with adverse neurodevelopmental outcomes in infants with congenital heart disease

Brain & development (Tokyo. 1979), 2008-08, Vol.30 (7), p.437-446

2008

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Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off

Experimental neurology, 2009-04, Vol.216 (2), p.383-389

2009

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Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

Epilepsy research, 2014-11, Vol.108 (9), p.1511-1518

2014

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RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS

Molecular and cellular neuroscience, 2011-07, Vol.47 (3), p.167-180

2011

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Sleep restriction alters the temporal expression of major histocompatibility complex class II molecules in murine lymphoid tissues

Behavioural brain research, 2019-04, Vol.362, p.152-159

2019

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Differential effect of D623N variant and wild-type Na(v)1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons

Brain research, 2013-09, Vol.1529, p.165-177

2013

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Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia

Pain (Amsterdam), 2013-10, Vol.154 (10), p.2216

2013

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Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties

Neuroscience letters, 2010-12, Vol.486 (2), p.84-91

2010

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Human cells and networks of pain: Transforming pain target identification and therapeutic development

Neuron (Cambridge, Mass.), 2021-05, Vol.109 (9), p.1426-1429

2021

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Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Na sub(v)1.6) in a mouse mutant with a chronic movement disorder

Neurobiology of disease, 2016-05, Vol.89, p.36-45

2016

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Sodium channels in pain disorders: pathophysiology and prospects for treatment

NaV1.7: A central role in pain

Sodium channel genes in pain-related disorders: phenotype–genotype associations and recommendations for clinical use

Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions

A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons

Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy

Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels

Recent advances for using human induced-pluripotent stem cells as pain-in-a-dish models of neuropathic pain

Mini-review - Sodium channels and beyond in peripheral nerve disease: Modulation by cytokines and their effector protein kinases

Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus

Nav1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation

Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain

Diversity of composition and function of sodium channels in peripheral sensory neurons

Human pain in a dish: Native DRG neurons and differentiated pluripotent stem cells

Factors associated with adverse neurodevelopmental outcomes in infants with congenital heart disease

Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off

Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS

Sleep restriction alters the temporal expression of major histocompatibility complex class II molecules in murine lymphoid tissues

Differential effect of D623N variant and wild-type Na(v)1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons

Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia

Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties

Human cells and networks of pain: Transforming pain target identification and therapeutic development

Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Na sub(v)1.6) in a mouse mutant with a chronic movement disorder

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