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Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification

Annual review of nutrition, 2009-01, Vol.29 (1), p.223-256

2009

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The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

The Journal of clinical investigation, 2003-05, Vol.111 (9), p.1409-1421

2003

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Noninvasive predictors of clinically significant portal hypertension in NASH cirrhosis: Validation of ANTICIPATE models and development of a lab‐based model

Hepatology communications, 2022-12, Vol.6 (12), p.3324-3334

2022

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The clinical approach to the detection of lipodystrophy - an AACE consensus statement

Endocrine practice, 2013-01, Vol.19 (1), p.107-116

2013

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Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (22), p.8481-8486

2006

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Crinecerfont, a CRF1 Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia

The journal of clinical endocrinology and metabolism, 2023-10, Vol.108 (11), p.2871-2878

2023

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Recombinant Human Leptin in Women with Hypothalamic Amenorrhea

The New England journal of medicine, 2004-09, Vol.351 (10), p.987-997

2004

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Recombinant Methionyl Human Leptin Therapy in Replacement Doses Improves Insulin Resistance and Metabolic Profile in Patients with Lipoatrophy and Metabolic Syndrome Induced by the Highly Active Antiretroviral Therapy

The journal of clinical endocrinology and metabolism, 2006-07, Vol.91 (7), p.2605-2611

2006

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Clinical classification and treatment of congenital and acquired lipodystrophy

Endocrine practice, 2010-03, Vol.16 (2), p.310-323

2010

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Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

The journal of clinical endocrinology and metabolism, 2003-06, Vol.88 (6), p.2838-2843

2003

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Rationale for leptin-replacement therapy for severe lipodystrophy

Endocrine practice, 2010-03, Vol.16 (2), p.324-333

2010

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Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: Observational and interventional studies in humans

Diabetes (New York, N.Y.), 2002-07, Vol.51 (7), p.2105-2112

2002

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Peptide YY Levels Are Elevated After Gastric Bypass Surgery

Obesity (Silver Spring, Md.), 2006-02, Vol.14 (2), p.194-198

2006

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The Q223R Polymorphism of the Leptin Receptor Gene Is Significantly Associated with Obesity and Predicts a Small Percentage of Body Weight and Body Composition Variability

The journal of clinical endocrinology and metabolism, 2001-09, Vol.86 (9), p.4434-4439

2001

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Leptin Does Not Mediate Short-Term Fasting-Induced Changes in Growth Hormone Pulsatility but Increases IGF-I in Leptin Deficiency States

The journal of clinical endocrinology and metabolism, 2008-07, Vol.93 (7), p.2819-2827

2008

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Ghrelin Levels Are Not Regulated by Recombinant Leptin Administration and/or Three Days of Fasting in Healthy Subjects

The journal of clinical endocrinology and metabolism, 2004-01, Vol.89 (1), p.335-343

2004

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Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States: Regulation by Gender and Adiposity

Clinical pharmacokinetics, 2008-01, Vol.47 (11), p.753-764

2008

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It Takes Two to Tango: Combined Amylin/Leptin Agonism as a Potential Approach to Obesity Drug Development

Journal of investigative medicine, 2009-10, Vol.57 (7), p.777-783

2009

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Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans

Clinical endocrinology (Oxford), 2007-01, Vol.66 (1), p.49-57

2007

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Pharmacokinetics of Recombinant Methionyl Human Leptin after Subcutaneous Administration: Variation of Concentration-Dependent Parameters According to Assay

The journal of clinical endocrinology and metabolism, 2007-06, Vol.92 (6), p.2307-2311

2007

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Pharmacological Management of Type 2 Diabetes Mellitus: Rationale for Rational Use of Insulin

Mayo Clinic proceedings, 2003-04, Vol.78 (4), p.459-467

2003

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Recombinant Methionyl Human Leptin Administration to Achieve High Physiologic or Pharmacologic Leptin Levels Does Not Alter Circulating Inflammatory Marker Levels in Humans with Leptin Sufficiency or Excess

The journal of clinical endocrinology and metabolism, 2005-03, Vol.90 (3), p.1618-1624

2005

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Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide

Diabetes care, 2008-05, Vol.31 (5), p.945-951

2008

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Circulating Melanin-Concentrating Hormone, Agouti-Related Protein, and α-Melanocyte-Stimulating Hormone Levels in Relation to Body Composition: Alterations in Response to Food Deprivation and Recombinant Human Leptin Administration

The journal of clinical endocrinology and metabolism, 2005-02, Vol.90 (2), p.1047-1054

2005

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Recombinant Methionyl Human Leptin Administration Activates Signal Transducer and Activator of Transcription 3 Signaling in Peripheral Blood Mononuclear Cells in Vivo and Regulates Soluble Tumor Necrosis Factor-α Receptor Levels in Humans with Relative Leptin Deficiency

The journal of clinical endocrinology and metabolism, 2005-03, Vol.90 (3), p.1625-1631

2005

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Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

Noninvasive predictors of clinically significant portal hypertension in NASH cirrhosis: Validation of ANTICIPATE models and development of a lab‐based model

The clinical approach to the detection of lipodystrophy - an AACE consensus statement

Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

Crinecerfont, a CRF1 Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia

Recombinant Human Leptin in Women with Hypothalamic Amenorrhea

Recombinant Methionyl Human Leptin Therapy in Replacement Doses Improves Insulin Resistance and Metabolic Profile in Patients with Lipoatrophy and Metabolic Syndrome Induced by the Highly Active Antiretroviral Therapy

Clinical classification and treatment of congenital and acquired lipodystrophy

Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

Rationale for leptin-replacement therapy for severe lipodystrophy

Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: Observational and interventional studies in humans

Peptide YY Levels Are Elevated After Gastric Bypass Surgery

The Q223R Polymorphism of the Leptin Receptor Gene Is Significantly Associated with Obesity and Predicts a Small Percentage of Body Weight and Body Composition Variability

Leptin Does Not Mediate Short-Term Fasting-Induced Changes in Growth Hormone Pulsatility but Increases IGF-I in Leptin Deficiency States

Ghrelin Levels Are Not Regulated by Recombinant Leptin Administration and/or Three Days of Fasting in Healthy Subjects

Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States: Regulation by Gender and Adiposity

It Takes Two to Tango: Combined Amylin/Leptin Agonism as a Potential Approach to Obesity Drug Development

Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans

Pharmacokinetics of Recombinant Methionyl Human Leptin after Subcutaneous Administration: Variation of Concentration-Dependent Parameters According to Assay

Pharmacological Management of Type 2 Diabetes Mellitus: Rationale for Rational Use of Insulin

Recombinant Methionyl Human Leptin Administration to Achieve High Physiologic or Pharmacologic Leptin Levels Does Not Alter Circulating Inflammatory Marker Levels in Humans with Leptin Sufficiency or Excess

Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide

Circulating Melanin-Concentrating Hormone, Agouti-Related Protein, and α-Melanocyte-Stimulating Hormone Levels in Relation to Body Composition: Alterations in Response to Food Deprivation and Recombinant Human Leptin Administration

Recombinant Methionyl Human Leptin Administration Activates Signal Transducer and Activator of Transcription 3 Signaling in Peripheral Blood Mononuclear Cells in Vivo and Regulates Soluble Tumor Necrosis Factor-α Receptor Levels in Humans with Relative Leptin Deficiency

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