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Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification

Annual review of nutrition, 2009-01, Vol.29 (1), p.223-256

2009

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The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

The Journal of clinical investigation, 2003-05, Vol.111 (9), p.1409-1421

2003

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Noninvasive predictors of clinically significant portal hypertension in NASH cirrhosis: Validation of ANTICIPATE models and development of a lab‐based model

Hepatology communications, 2022-12, Vol.6 (12), p.3324-3334

2022

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The clinical approach to the detection of lipodystrophy - an AACE consensus statement

Endocrine practice, 2013-01, Vol.19 (1), p.107-116

2013

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Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (22), p.8481-8486

2006

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Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non‐alcoholic fatty liver disease

Alimentary pharmacology & therapeutics, 2019-01, Vol.49 (1), p.64-73

2019

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Emricasan (IDN‐6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.717-728

2019

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Recombinant Human Leptin in Women with Hypothalamic Amenorrhea

The New England journal of medicine, 2004-09, Vol.351 (10), p.987-997

2004

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Phase 3 Trial of Crinecerfont in Adult Congenital Adrenal Hyperplasia

The New England journal of medicine, 2024-08, Vol.391 (6), p.504-514

2024

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Multicenter, Double‐Blind, Randomized Trial of Emricasan in Hepatitis C–Treated Liver Transplant Recipients With Residual Fibrosis or Cirrhosis

Liver transplantation, 2021-04, Vol.27 (4), p.568-579

2021

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Serum Adiponectin Levels Are Inversely Associated with Overall and Central Fat Distribution but Are Not Directly Regulated by Acute Fasting or Leptin Administration in Humans: Cross-Sectional and Interventional Studies

The journal of clinical endocrinology and metabolism, 2003-10, Vol.88 (10), p.4823-4831

2003

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Clinical classification and treatment of congenital and acquired lipodystrophy

Endocrine practice, 2010-03, Vol.16 (2), p.310-323

2010

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Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

The journal of clinical endocrinology and metabolism, 2003-06, Vol.88 (6), p.2838-2843

2003

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Rationale for leptin-replacement therapy for severe lipodystrophy

Endocrine practice, 2010-03, Vol.16 (2), p.324-333

2010

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Peptide YY Levels Are Elevated After Gastric Bypass Surgery

Obesity (Silver Spring, Md.), 2006-02, Vol.14 (2), p.194-198

2006

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Leptin Does Not Mediate Short-Term Fasting-Induced Changes in Growth Hormone Pulsatility but Increases IGF-I in Leptin Deficiency States

The journal of clinical endocrinology and metabolism, 2008-07, Vol.93 (7), p.2819-2827

2008

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Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States: Regulation by Gender and Adiposity

Clinical pharmacokinetics, 2008-01, Vol.47 (11), p.753-764

2008

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It Takes Two to Tango: Combined Amylin/Leptin Agonism as a Potential Approach to Obesity Drug Development

Journal of investigative medicine, 2009-10, Vol.57 (7), p.777-783

2009

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Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans

Clinical endocrinology (Oxford), 2007-01, Vol.66 (1), p.49-57

2007

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Pharmacokinetics of Recombinant Methionyl Human Leptin after Subcutaneous Administration: Variation of Concentration-Dependent Parameters According to Assay

The journal of clinical endocrinology and metabolism, 2007-06, Vol.92 (6), p.2307-2311

2007

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Pharmacological Management of Type 2 Diabetes Mellitus: Rationale for Rational Use of Insulin

Mayo Clinic proceedings, 2003-04, Vol.78 (4), p.459-467

2003

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Recombinant Methionyl Human Leptin Administration to Achieve High Physiologic or Pharmacologic Leptin Levels Does Not Alter Circulating Inflammatory Marker Levels in Humans with Leptin Sufficiency or Excess

The journal of clinical endocrinology and metabolism, 2005-03, Vol.90 (3), p.1618-1624

2005

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Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide

Diabetes care, 2008-05, Vol.31 (5), p.945-951

2008

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Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide: Interventional studies in humans

Diabetes care, 2008-05, Vol.31 (5), p.945-951

2008

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r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans

European journal of endocrinology, 2009-02, Vol.160 (2), p.173-176

2009

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Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

Noninvasive predictors of clinically significant portal hypertension in NASH cirrhosis: Validation of ANTICIPATE models and development of a lab‐based model

The clinical approach to the detection of lipodystrophy - an AACE consensus statement

Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non‐alcoholic fatty liver disease

Emricasan (IDN‐6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension

Recombinant Human Leptin in Women with Hypothalamic Amenorrhea

Phase 3 Trial of Crinecerfont in Adult Congenital Adrenal Hyperplasia

Multicenter, Double‐Blind, Randomized Trial of Emricasan in Hepatitis C–Treated Liver Transplant Recipients With Residual Fibrosis or Cirrhosis

Serum Adiponectin Levels Are Inversely Associated with Overall and Central Fat Distribution but Are Not Directly Regulated by Acute Fasting or Leptin Administration in Humans: Cross-Sectional and Interventional Studies

Clinical classification and treatment of congenital and acquired lipodystrophy

Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

Rationale for leptin-replacement therapy for severe lipodystrophy

Peptide YY Levels Are Elevated After Gastric Bypass Surgery

Leptin Does Not Mediate Short-Term Fasting-Induced Changes in Growth Hormone Pulsatility but Increases IGF-I in Leptin Deficiency States

Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States: Regulation by Gender and Adiposity

It Takes Two to Tango: Combined Amylin/Leptin Agonism as a Potential Approach to Obesity Drug Development

Short-term fasting-induced autonomic activation and changes in catecholamine levels are not mediated by changes in leptin levels in healthy humans

Pharmacokinetics of Recombinant Methionyl Human Leptin after Subcutaneous Administration: Variation of Concentration-Dependent Parameters According to Assay

Pharmacological Management of Type 2 Diabetes Mellitus: Rationale for Rational Use of Insulin

Recombinant Methionyl Human Leptin Administration to Achieve High Physiologic or Pharmacologic Leptin Levels Does Not Alter Circulating Inflammatory Marker Levels in Humans with Leptin Sufficiency or Excess

Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide

Leptin Does Not Directly Regulate the Pancreatic Hormones Amylin and Pancreatic Polypeptide: Interventional studies in humans

r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans

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