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Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy

Clinical oncology (Royal College of Radiologists (Great Britain)), 2013-10, Vol.25 (10), p.578-585

2013

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Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy

Biochemical pharmacology, 2001-01, Vol.61 (2), p.129-136

2001

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Toward targeted “oxidation therapy” of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids

International journal of radiation oncology, biology, physics, 1998-11, Vol.42 (4), p.917-920

1998

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Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro

Biochemical pharmacology, 1999-02, Vol.57 (4), p.375-382

1999

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Free-Radical Repair by a Novel Perthiol: Reversible Hydrogen Transfer and Perthiyl Radical Formation

Free radical research, 1994-01, Vol.20 (6), p.387-400

1994

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Kinetics and Mechanisms of Hypochlorous Acid Reactions

Archives of biochemistry and biophysics, 1995-10, Vol.323 (1), p.120-126

1995

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Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.151-160

2001

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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

Cancer gene therapy, 2000-11, Vol.7 (11), p.1414-1420

2000

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Interpretation of the reactivity of peroxidase compounds I and II with phenols by the Marcus equation

FEBS letters, 1997-07, Vol.412 (2), p.305-308

1997

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Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents

Clinica chimica acta, 2001-12, Vol.314 (1), p.159-166

2001

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Factors Controlling the Substrate Specificity of Peroxidases: Kinetics and Thermodynamics of the Reaction of Horseradish Peroxidase Compound I with Phenols and Indole-3-acetic Acids

Biochemistry (Easton), 1997-06, Vol.36 (23), p.7081-7085

1997

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Enhancement of peroxidase-induced lipid peroxidation by indole-3-acetic acid: effect of antioxidants

Redox report : communications in free radical research, 1996-04, Vol.2 (2), p.141-147

1996

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Reactivity toward Thiols and Cytotoxicity of 3-Methylene-2-oxindoles, Cytotoxins from Indole-3-acetic Acids, on Activation by Peroxidases

Chemical research in toxicology, 2002-06, Vol.15 (6), p.877-882

2002

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Rates of Reaction of Indoleacetic Acids with Horseradish Peroxidase Compound I and Their Dependence on the Redox Potentials

Biochemistry (Easton), 1996-01, Vol.35 (1), p.102-108

1996

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Influence of plasma glutathione levels on radiation mucositis

International journal of radiation oncology, biology, physics, 2001-10, Vol.51 (2), p.460-464

2001

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Revisiting the Interaction of the Radical Anion Metabolite of Nitrofurantoin with Glutathione

Archives of biochemistry and biophysics, 2002-01, Vol.397 (1), p.113-118

2002

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Enhancement of Lipid Peroxidation by Indole-3-Acetic Acid and Derivatives: Substituent Effects

Free radical research, 1995-01, Vol.23 (5), p.403-418

1995

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Amplification of oxidative stress by decarboxylation: a new strategy in anti-tumour drug design

Biochemical Society transactions, 1995-05, Vol.23 (2), p.262S-262S

1995

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Kinetics of the reaction between nitric oxide and glutathione: implications for thiol depletion in cells

Free radical biology & medicine, 2004-08, Vol.37 (4), p.549-556

2004

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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

Cancer gene therapy, 2000-11, Vol.7 (11), p.1414-1420

2000

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Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2523-2526

2002

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5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy

Biochemical pharmacology, 2002-01, Vol.63 (2), p.265-272

2002

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Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy

Radiotherapy and oncology, 2002-06, Vol.63 (3), p.285-291

2002

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Free-Radical Intermediates and Stable Products in the Oxidation of Indole-3-acetic acid

Journal of physical chemistry (1952), 1994-10, Vol.98 (40), p.10131-10137

1994

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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Cell chemical biology, 2021-09, Vol.28 (9), p.1258-1270.e13

2021

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Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy

Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy

Toward targeted “oxidation therapy” of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids

Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro

Free-Radical Repair by a Novel Perthiol: Reversible Hydrogen Transfer and Perthiyl Radical Formation

Kinetics and Mechanisms of Hypochlorous Acid Reactions

Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions

Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

Interpretation of the reactivity of peroxidase compounds I and II with phenols by the Marcus equation

Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents

Factors Controlling the Substrate Specificity of Peroxidases: Kinetics and Thermodynamics of the Reaction of Horseradish Peroxidase Compound I with Phenols and Indole-3-acetic Acids

Enhancement of peroxidase-induced lipid peroxidation by indole-3-acetic acid: effect of antioxidants

Reactivity toward Thiols and Cytotoxicity of 3-Methylene-2-oxindoles, Cytotoxins from Indole-3-acetic Acids, on Activation by Peroxidases

Rates of Reaction of Indoleacetic Acids with Horseradish Peroxidase Compound I and Their Dependence on the Redox Potentials

Influence of plasma glutathione levels on radiation mucositis

Revisiting the Interaction of the Radical Anion Metabolite of Nitrofurantoin with Glutathione

Enhancement of Lipid Peroxidation by Indole-3-Acetic Acid and Derivatives: Substituent Effects

Amplification of oxidative stress by decarboxylation: a new strategy in anti-tumour drug design

Kinetics of the reaction between nitric oxide and glutathione: implications for thiol depletion in cells

Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy

5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy

Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy

Free-Radical Intermediates and Stable Products in the Oxidation of Indole-3-acetic acid

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

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