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“Designer cytokines” targeting the tumor vasculature—think global and act local

EMBO molecular medicine, 2020-02, Vol.12 (2), p.e11801-n/a

2020

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Early-Life Stress Regulates Cardiac Development through an IL-4-Glucocorticoid Signaling Balance

Cell reports (Cambridge), 2020-11, Vol.33 (7), p.108404-108404, Article 108404

2020

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Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

PloS one, 2020-09, Vol.15 (9), p.e0239231-e0239231

2020

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Composition of intestinal microbiota in immune-deficient mice kept in three different housing conditions

PloS one, 2014-11, Vol.9 (11), p.e113406-e113406

2014

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Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

Animals (Basel), 2021-06, Vol.11 (6), p.1789

2021

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Making and circumventing tolerance to cancer

European journal of immunology, 2009-09, Vol.39 (9), p.2345-2353

2009

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Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors

Cancer immunology research, 2020-02, Vol.8 (2), p.192-202

2020

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Targeting c-MYC with T-cells

PloS one, 2013-10, Vol.8 (10), p.e77375-e77375

2013

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It’s the Peptide-MHC Affinity, Stupid

Cancer cell, 2013-04, Vol.23 (4), p.429-431

2013

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Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice

PloS one, 2012-03, Vol.7 (3), p.e34552-e34552

2012

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Targeting human melanoma neoantigens by T cell receptor gene therapy

The Journal of clinical investigation, 2016-03, Vol.126 (3), p.854-858

2016

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Oligonucleotide library screening for identification of virus‐specific T‐cell receptors

European journal of immunology, 2024-06, Vol.54 (6), p.e2350908-n/a

2024

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IFNγ binding to extracellular matrix prevents fatal systemic toxicity

Nature immunology, 2023-03, Vol.24 (3), p.414

2023

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Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis

International journal of cancer, 2011-01, Vol.128 (2), p.371-378

2011

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IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

Science advances, 2022-06, Vol.8 (23), p.eabl5162-eabl5162

2022

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Oncogene-Targeting T Cells Reject Large Tumors while Oncogene Inactivation Selects Escape Variants in Mouse Models of Cancer

Cancer cell, 2011-12, Vol.20 (6), p.755-767

2011

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B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin)

International journal of cancer, 2012-10, Vol.131 (7), p.1499-1508

2012

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Immunotherapy: target the stroma to hit the tumor

Trends in molecular medicine, 2005-05, Vol.11 (5), p.225-231

2005

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Dr. Käthe Beutler, 1896–1999: A German Born Jewish Physician and Her Family Between Science, Politics and Prejudice

Medizinhistorisches Journal, 2019-12, Vol.54 (4), p.294-346

2019

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Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia

Journal of molecular medicine (Berlin, Germany), 2010-03, Vol.88 (3), p.249-265

2010

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Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates

Cytokine (Philadelphia, Pa.), 2012-12, Vol.60 (3), p.626-633

2012

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Targeting high‐grade B cell lymphoma with CD19‐specific T cells

International journal of cancer, 2014-09, Vol.135 (5), p.1153-1164

2014

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Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

PloS one, 2020-01, Vol.15 (9)

2020

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Tumor‐induced antibodies resemble the response to tissue damage

International journal of cancer, 2005-06, Vol.115 (3), p.456-462

2005

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Stromal Interferon-[gamma] Signaling and Cross-Presentation Are Required to Eliminate Antigen-Loss Variants of B Cell Lymphomas in Mice

PloS one, 2012-03, Vol.7 (3), p.e34552

2012

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“Designer cytokines” targeting the tumor vasculature—think global and act local

Early-Life Stress Regulates Cardiac Development through an IL-4-Glucocorticoid Signaling Balance

Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

Composition of intestinal microbiota in immune-deficient mice kept in three different housing conditions

Breeding and Maintenance of Immunodeficient Mouse Lines under SPF Conditions—A Call for Individualized Severity Analyses and Approval Procedures

Making and circumventing tolerance to cancer

Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors

Targeting c-MYC with T-cells

It’s the Peptide-MHC Affinity, Stupid

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice

Targeting human melanoma neoantigens by T cell receptor gene therapy

Oligonucleotide library screening for identification of virus‐specific T‐cell receptors

IFNγ binding to extracellular matrix prevents fatal systemic toxicity

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

Oncogene-Targeting T Cells Reject Large Tumors while Oncogene Inactivation Selects Escape Variants in Mouse Models of Cancer

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin)

Immunotherapy: target the stroma to hit the tumor

Dr. Käthe Beutler, 1896–1999: A German Born Jewish Physician and Her Family Between Science, Politics and Prejudice

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia

Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates

Targeting high‐grade B cell lymphoma with CD19‐specific T cells

Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

Tumor‐induced antibodies resemble the response to tissue damage

Stromal Interferon-[gamma] Signaling and Cross-Presentation Are Required to Eliminate Antigen-Loss Variants of B Cell Lymphomas in Mice

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