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The role of heat shock proteins and co-chaperones in heart failure

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-01, Vol.373 (1738), p.20160530

2018

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Autophagy and p62 in Cardiac Proteinopathy

Circulation research, 2011-07, Vol.109 (3), p.296-308

2011

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Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction

The Journal of experimental medicine, 2016-06, Vol.213 (7), p.1353-1374

2016

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CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury

Nature communications, 2020-10, Vol.11 (1), p.5237-5237, Article 5237

2020

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COP9 Signalosome Regulates Autophagosome Maturation

Circulation (New York, N.Y.), 2011-11, Vol.124 (19), p.2117-2128

2011

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In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (20), p.10156-10161

2019

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Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

Nature communications, 2018-12, Vol.9 (1), p.5230-12, Article 5230

2018

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Pulmonary artery pulsatility index predicts right ventricular myofilament dysfunction in advanced human heart failure

European journal of heart failure, 2021-02, Vol.23 (2), p.339-341

2021

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Protein Kinase G Positively Regulates Proteasome-Mediated Degradation of Misfolded Proteins

Circulation (New York, N.Y.), 2013-07, Vol.128 (4), p.365-376

2013

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Protein quality control and degradation in cardiomyocytes

Journal of molecular and cellular cardiology, 2008-07, Vol.45 (1), p.11-27

2008

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Editorial: Post-translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease

Frontiers in physiology, 2021-08, Vol.12, p.745887-745887

2021

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PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy

Circulation research, 2020-07, Vol.127 (4), p.522-533

2020

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Editorial: Targeting Cardiac Proteotoxicity

Frontiers in physiology, 2021-03, Vol.12, p.669356-669356

2021

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MTORC1-Regulated Metabolism Controlled by TSC2 Limits Cardiac Reperfusion Injury

Circulation research, 2021-03, Vol.128 (5), p.639-651

2021

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Prevention of PKG1α oxidation augments cardioprotection in the stressed heart

The Journal of clinical investigation, 2015-06, Vol.125 (6), p.2468-2472

2015

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Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms

Frontiers in physiology, 2020-11, Vol.11, p.593585-593585

2020

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Growth hormone–releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (48), p.e2308342120-e2308342120

2023

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Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload

Journal of molecular and cellular cardiology, 2015-08, Vol.85, p.273-281

2015

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Soluble Guanylate Cyclase Is Required for Systemic Vasodilation But Not Positive Inotropy Induced by Nitroxyl in the Mouse

Hypertension (Dallas, Tex. 1979), 2015-02, Vol.65 (2), p.385-392

2015

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Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation

Circulation. Heart failure, 2018-03, Vol.11 (3), p.e004740-e004740

2018

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Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy

Current hypertension reports, 2009-12, Vol.11 (6), p.389-395

2009

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Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner

Journal of molecular and cellular cardiology, 2014-04, Vol.69, p.43-51

2014

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TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy

JCI insight, 2023-11, Vol.8 (21)

2023

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Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease

JCI insight, 2018-08, Vol.3 (15)

2018

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The role of heat shock proteins and co-chaperones in heart failure

Autophagy and p62 in Cardiac Proteinopathy

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction

CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury

COP9 Signalosome Regulates Autophagosome Maturation

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease

Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

Pulmonary artery pulsatility index predicts right ventricular myofilament dysfunction in advanced human heart failure

Protein Kinase G Positively Regulates Proteasome-Mediated Degradation of Misfolded Proteins

Protein quality control and degradation in cardiomyocytes

Editorial: Post-translational Modifications and Compartmentalized Protein Quality Control in Cardiac Muscle and Disease

PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy

Editorial: Targeting Cardiac Proteotoxicity

MTORC1-Regulated Metabolism Controlled by TSC2 Limits Cardiac Reperfusion Injury

Prevention of PKG1α oxidation augments cardioprotection in the stressed heart

Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms

Growth hormone–releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice

Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload

Soluble Guanylate Cyclase Is Required for Systemic Vasodilation But Not Positive Inotropy Induced by Nitroxyl in the Mouse

Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation

Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy

Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner

A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8

TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy

Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease

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