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A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine

Proceedings of the National Academy of Sciences - PNAS, 2024-11, Vol.121 (45), p.e2411189121

2024

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Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry

Nature communications, 2024-10, Vol.15 (1), p.8993-14, Article 8993

2024

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Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β2 adrenergic receptors

Cellular & molecular biology letters, 2024-10, Vol.29 (1), p.132-23, Article 132

2024

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Structural basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB

Nature communications, 2024-10, Vol.15 (1), p.9316-16, Article 9316

2024

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Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β 2 adrenergic receptors

Cellular & molecular biology letters, 2024-10, Vol.29 (1), p.132

2024

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Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action

Journal of headache and pain, 2024-10, Vol.25 (1), p.187-17, Article 187

2024

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Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (44), p.e2405085121

2024

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Unveiling the critical role of androgen receptor signaling in avian sexual development

Nature communications, 2024-10, Vol.15 (1), p.8970-12, Article 8970

2024

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A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1

Nature communications, 2024-10, Vol.15 (1), p.9040-13, Article 9040

2024

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Deficiency of GPR10 and NPFFR2 receptors leads to sex-specific prediabetic syndrome and late-onset obesity in mice

Bioscience reports, 2024-10, Vol.44 (10)

2024

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Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes

Nature communications, 2024-10, Vol.15 (1), p.9204-16, Article 9204

2024

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Structure of G protein-coupled receptor GPR1 bound to full-length chemerin adipokine reveals a chemokine-like reverse binding mode

PLoS biology, 2024-10, Vol.22 (10), p.e3002838

2024

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AMBRA1 controls the translation of immune-specific genes in T lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (44), p.e2416722121

2024

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Oncolytic Viruses as Reliable Adjuvants in CAR-T Cell Therapy for Solid Tumors

International journal of molecular sciences, 2024-10, Vol.25 (20), p.11127

2024

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Antagonist of Growth Hormone-Releasing Hormone Receptor MIA-690 Suppresses the Growth of Androgen-Independent Prostate Cancers

International journal of molecular sciences, 2024-10, Vol.25 (20), p.11200

2024

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Targeting Unc5b in macrophages drives atherosclerosis regression and pro-resolving immune cell function

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (44), p.e2412690121

2024

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n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs

PloS one, 2024-11, Vol.19 (11), p.e0311573

2024

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Modulation of Ca2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis

Scientific reports, 2024-11, Vol.14 (1), p.27667, Article 27667

2024

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Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M

Nature communications, 2024-10, Vol.15 (1), p.9387-10, Article 9387

2024

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Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice

Nature communications, 2024-10, Vol.15 (1), p.9093-17, Article 9093

2024

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Single molecule tracking based drug screening

Nature communications, 2024-10, Vol.15 (1), p.8975-14, Article 8975

2024

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Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking

Scientific reports, 2024-10, Vol.14 (1), p.25738-16, Article 25738

2024

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Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance

Nature communications, 2024-10, Vol.15 (1), p.9056-13, Article 9056

2024

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TNF receptors: Structure-function relationships and therapeutic targeting strategies

Biochimica et biophysica acta. Biomembranes, 2025-01, Vol.1867 (1), p.184394, Article 184394

Lo, Chih Hung

2025

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Biochemical analysis of EGFR exon20 insertion variants insASV and insSVD and their inhibitor sensitivity

Proceedings of the National Academy of Sciences - PNAS, 2024-11, Vol.121 (45), p.e2417144121

2024

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A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine

Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry

Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β2 adrenergic receptors

Structural basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB

Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β 2 adrenergic receptors

Regional distribution of unbound eletriptan and sumatriptan in the CNS and PNS in rats: implications for a potential central action

Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs

Unveiling the critical role of androgen receptor signaling in avian sexual development

A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1

Deficiency of GPR10 and NPFFR2 receptors leads to sex-specific prediabetic syndrome and late-onset obesity in mice

Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes

Structure of G protein-coupled receptor GPR1 bound to full-length chemerin adipokine reveals a chemokine-like reverse binding mode

AMBRA1 controls the translation of immune-specific genes in T lymphocytes

Oncolytic Viruses as Reliable Adjuvants in CAR-T Cell Therapy for Solid Tumors

Antagonist of Growth Hormone-Releasing Hormone Receptor MIA-690 Suppresses the Growth of Androgen-Independent Prostate Cancers

Targeting Unc5b in macrophages drives atherosclerosis regression and pro-resolving immune cell function

n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs

Modulation of Ca2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis

Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M

Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice

Single molecule tracking based drug screening

Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking

Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance

TNF receptors: Structure-function relationships and therapeutic targeting strategies

Biochemical analysis of EGFR exon20 insertion variants insASV and insSVD and their inhibitor sensitivity

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