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Smallpox in the Post-Eradication Era

Viruses, 2020-01, Vol.12 (2), p.138

2020

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Research with variola virus after smallpox eradication: Development of a mouse model for variola virus infection

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009911-e1009911

2021

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The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling

PLoS pathogens, 2022-02, Vol.18 (2), p.e1010277-e1010277

2022

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Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies

PLoS pathogens, 2022-06, Vol.18 (6), p.e1010612-e1010612

2022

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DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation

Viruses, 2022-02, Vol.14 (2), p.316

2022

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Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

PLoS pathogens, 2016-12, Vol.12 (12), p.e1005955-e1005955

2016

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HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113788-113788, Article 113788

2024

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Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response

PLoS pathogens, 2022-04, Vol.18 (4), p.e1009854-e1009854

2022

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Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

PLoS pathogens, 2011-09, Vol.7 (9), p.e1002247-e1002247

2011

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Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

Frontiers in microbiology, 2022-11, Vol.13, p.1027015-1027015

2022

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DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing

Cell reports (Cambridge), 2018-11, Vol.25 (7), p.1953-1965.e4

2018

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Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist

Cell reports (Cambridge), 2019-05, Vol.27 (6), p.1920-1933.e7

2019

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A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus

PLoS pathogens, 2013-10, Vol.9 (10), p.e1003649-e1003649

2013

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Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory

Viruses, 2018-02, Vol.10 (3), p.101

2018

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Transcriptional reprogramming of natural killer cells by vaccinia virus shows both distinct and conserved features with mCMV

Frontiers in immunology, 2023-02, Vol.14, p.1093381-1093381

2023

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Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003183

2013

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Enhanced Efficacy of Vaccination With Vaccinia Virus in Old vs. Young Mice

Frontiers in immunology, 2019-07, Vol.10, p.1780-1780

2019

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Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

PLoS pathogens, 2015-09, Vol.11 (9), p.e1005151

2015

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Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism

Redox biology, 2020-01, Vol.28, p.101361, Article 101361

2020

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Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination

Cell reports (Cambridge), 2023-05, Vol.42 (5), p.112470, Article 112470

2023

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Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination

Nature medicine, 2006-11, Vol.12 (11), p.1310-1315

2006

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Vaccinia virus protein complex F12/E2 interacts with kinesin light chain isoform 2 to engage the kinesin-1 motor complex

PLoS pathogens, 2015-03, Vol.11 (3), p.e1004723-e1004723

2015

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Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence

PLoS pathogens, 2011-12, Vol.7 (12), p.e1002430

2011

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Vaccinia virus proteins A36 and F12/E2 show strong preferences for different kinesin light chain isoforms

Traffic (Copenhagen, Denmark), 2017-08, Vol.18 (8), p.505-518

2017

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A new inhibitor of apoptosis from vaccinia virus and eukaryotes

PLoS pathogens, 2007-02, Vol.3 (2), p.e17-e17

2007

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Smallpox in the Post-Eradication Era

Research with variola virus after smallpox eradication: Development of a mouse model for variola virus infection

The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling

Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies

DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation

Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus

Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response

Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins

DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing

Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist

A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus

Modulating Vaccinia Virus Immunomodulators to Improve Immunological Memory

Transcriptional reprogramming of natural killer cells by vaccinia virus shows both distinct and conserved features with mCMV

Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

Enhanced Efficacy of Vaccination With Vaccinia Virus in Old vs. Young Mice

Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence

Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination

Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination

Vaccinia virus protein complex F12/E2 interacts with kinesin light chain isoform 2 to engage the kinesin-1 motor complex

Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence

Vaccinia virus proteins A36 and F12/E2 show strong preferences for different kinesin light chain isoforms

A new inhibitor of apoptosis from vaccinia virus and eukaryotes

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