UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 167

Sortiert nach

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Frontiers in microbiology, 2018-07, Vol.9, p.1367-1367

2018

Link zum Volltext

Verfügbarkeit prüfen

Indoleamides are active against drug-resistant Mycobacterium tuberculosis

Nature communications, 2013-12, Vol.4 (1), Article 2907

2013

Link zum Volltext

Verfügbarkeit prüfen

Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy

Current medicinal chemistry, 2015-01, Vol.22 (2), p.187

2015

Link zum Volltext

Verfügbarkeit prüfen

Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Biochemical journal, 2019-12, Vol.476 (24), p.3751-3768

2019

Link zum Volltext

Verfügbarkeit prüfen

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

Pharmaceutics, 2019-05, Vol.11 (5), p.203

2019

Link zum Volltext

Verfügbarkeit prüfen

Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1)

Expert opinion on therapeutic patents, 2020-12, Vol.30 (12), p.901-905

Pieroni, Marco

2020

Link zum Volltext

Verfügbarkeit prüfen

Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

Pharmaceuticals (Basel, Switzerland), 2022-06, Vol.15 (6), p.766

2022

Link zum Volltext

Verfügbarkeit prüfen

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.31-43

2019

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

Pharmaceuticals (Basel, Switzerland), 2021-02, Vol.14 (2), p.174

2021

Link zum Volltext

Verfügbarkeit prüfen

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1444-1452

2018

Link zum Volltext

Verfügbarkeit prüfen

Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1537-1544

2018

Link zum Volltext

Verfügbarkeit prüfen

A Competitive O-Acetylserine Sulfhydrylase Inhibitor Modulates the Formation of Cysteine Synthase Complex

Catalysts, 2021-06, Vol.11 (6), p.700

2021

Link zum Volltext

Verfügbarkeit prüfen

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

Antibiotics (Basel), 2018-03, Vol.7 (1), p.18

2018

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of 7-Desmethyl Analogs of (+)- and (−)-Huperzine A

Heterocycles, 2015, Vol.91 (12), p.2285

2015

Link zum Volltext

Verfügbarkeit prüfen

Novel N-Benzoyl-2-Hydroxybenzamide Disrupts Unique Parasite Secretory Pathway

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2666-2682

2012

Link zum Volltext

Verfügbarkeit prüfen

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Frontiers in molecular biosciences, 2018-11, Vol.5, p.104-104

2018

Link zum Volltext

Verfügbarkeit prüfen

Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

Journal of medicinal chemistry, 2022-07, Vol.65 (14), p.9718-9734

2022

Link zum Volltext

Verfügbarkeit prüfen

Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure–Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.1959-1970

2017

Link zum Volltext

Verfügbarkeit prüfen

Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation

Mucosal immunology, 2018-07, Vol.11 (4), p.1060-1070

2018

Link zum Volltext

Verfügbarkeit prüfen

Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

Proteins, structure, function, and bioinformatics, 2022-02, Vol.90 (2), p.435-442

2022

Link zum Volltext

Verfügbarkeit prüfen

Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets

Journal of chemical information and modeling, 2018-03, Vol.58 (3), p.710-723

2018

Link zum Volltext

Verfügbarkeit prüfen

2‑Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry

ACS medicinal chemistry letters, 2020-07, Vol.11 (7), p.1435-1441

2020

Link zum Volltext

Verfügbarkeit prüfen

Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor

ACS medicinal chemistry letters, 2024-07

2024

Link zum Volltext

Verfügbarkeit prüfen

Rational Design, Synthesis, and Preliminary Structure–Activity Relationships of α‑Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O‑Acetylserine Sulfhydrylase

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2567-2578

2016

Link zum Volltext

Verfügbarkeit prüfen

Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit–to–lead optimization and release of a novel antitubercular chemotype via scaffold derivatization

European journal of medicinal chemistry, 2023-01, Vol.245 (Pt 2), p.114916-114916, Article 114916

2023

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 167

Suche als RSS-Feed

Aktive Filter

KollektionOxford journals

ThemaMycobacterium Tuberculosis - Drug Effects

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(153)
Mit Volltextzugriff
(150)

Publikationsform

Sprache

1 weiteren anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(8)

Menü

Weitere Dienste

Einstellungen

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Indoleamides are active against drug-resistant Mycobacterium tuberculosis

Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy

Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1)

Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design

Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases

A Competitive O-Acetylserine Sulfhydrylase Inhibitor Modulates the Formation of Cysteine Synthase Complex

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

Synthesis of 7-Desmethyl Analogs of (+)- and (−)-Huperzine A

Novel N-Benzoyl-2-Hydroxybenzamide Disrupts Unique Parasite Secretory Pathway

Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase

Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure–Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents

Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation

Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase

Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets

2‑Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry

Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor

Rational Design, Synthesis, and Preliminary Structure–Activity Relationships of α‑Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella typhimurium O‑Acetylserine Sulfhydrylase

Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit–to–lead optimization and release of a novel antitubercular chemotype via scaffold derivatization

Aktive Filter

Suchergebnisse filtern