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Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells

Nature communications, 2018-03, Vol.9 (1), p.948-9, Article 948

2018

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Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth

Nature communications, 2021-01, Vol.12 (1), p.683-16, Article 683

2021

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Modeling the Therapeutic Efficacy of p53 Restoration in Tumors

Cell, 2006-12, Vol.127 (7), p.1323-1334

2006

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The ERBB network facilitates KRAS-driven lung tumorigenesis

Science translational medicine, 2018-06, Vol.10 (446)

2018

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Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

Nature communications, 2020-09, Vol.11 (1), p.4903-16, Article 4903

2020

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Exploring the role of stromal osmoregulation in cancer and disease using executable modelling

Nature communications, 2018-08, Vol.9 (1), p.3011-15, Article 3011

2018

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Validation of MdmX as a therapeutic target for reactivating p53 in tumors

Genes & development, 2011-08, Vol.25 (16), p.1746-1757

2011

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Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

Nature (London), 2016-03, Vol.531 (7592), p.110-113

2016

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Metabolic rewiring in mutant Kras lung cancer

The FEBS journal, 2018-01, Vol.285 (1), p.28-41

2018

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Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress

PloS one, 2013-09, Vol.8 (9), p.e73817

2013

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Modelling Myc inhibition as a cancer therapy

Nature, 2008-10, Vol.455 (7213), p.679-683

2008

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Selective activation of p53-mediated tumour suppression in high-grade tumours

Nature (London), 2010-11, Vol.468 (7323), p.567-571

2010

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Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

Genes & development, 2017-07, Vol.31 (13), p.1339-1353

2017

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AZD4625 is a Potent and Selective Inhibitor of KRASG12C

Molecular cancer therapeutics, 2022-10, Vol.21 (10), p.1535-1546

2022

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From tumor prevention to therapy: Empowering p53 to fight back

Drug resistance updates, 2012-10, Vol.15 (5), p.258-267

2012

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KRAS Allelic Imbalance: Strengths and Weaknesses in Numbers

Trends in molecular medicine, 2017-05, Vol.23 (5), p.377-378

2017

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Late Imaging with [1-(11)C]Acetate Improves Detection of Tumor Fatty Acid Synthesis with PET

Journal of Nuclear Medicine, 2014-07, Vol.55 (7), p.1144-1149

2014

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Abstract IA14: Exploiting the metabolic dependencies of mutant Kras lung tumors

Molecular cancer research, 2020-05, Vol.18 (5_Supplement), p.IA14-IA14

Martins, Carla P.

2020

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Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis

The EMBO journal, 2002-07, Vol.21 (14), p.3739-3748

2002

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Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (17), p.11293-11298

2002

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Insertional Mutagenesis in Mice Deficient for p15Ink4b,p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes

Cancer research (Chicago, Ill.), 2010-01, Vol.70 (2), p.520-531

2010

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Abstract 1619: Characterising the in vivo response of lung tumors to KrasG12C inhibition

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1619-1619

2020

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Abstract 5504: A tumor-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5504-5504

2023

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Loss of p27 Kip1 but not p21 Cip1 decreases survival and synergizes with MYC in murine lymphomagenesis

The EMBO journal, 2002-07, Vol.21 (14), p.3739-3748

2002

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Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells

Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth

Modeling the Therapeutic Efficacy of p53 Restoration in Tumors

Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity

The ERBB network facilitates KRAS-driven lung tumorigenesis

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

Exploring the role of stromal osmoregulation in cancer and disease using executable modelling

Validation of MdmX as a therapeutic target for reactivating p53 in tumors

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

Metabolic rewiring in mutant Kras lung cancer

Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress

Modelling Myc inhibition as a cancer therapy

Selective activation of p53-mediated tumour suppression in high-grade tumours

Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity

AZD4625 is a Potent and Selective Inhibitor of KRASG12C

From tumor prevention to therapy: Empowering p53 to fight back

KRAS Allelic Imbalance: Strengths and Weaknesses in Numbers

Late Imaging with [1-(11)C]Acetate Improves Detection of Tumor Fatty Acid Synthesis with PET

Abstract IA14: Exploiting the metabolic dependencies of mutant Kras lung tumors

Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis

Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis

Insertional Mutagenesis in Mice Deficient for p15Ink4b,p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes

Abstract 1619: Characterising the in vivo response of lung tumors to KrasG12C inhibition

Abstract 5504: A tumor-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer

Loss of p27 Kip1 but not p21 Cip1 decreases survival and synergizes with MYC in murine lymphomagenesis

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