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A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors

Organic & biomolecular chemistry, 2021-02, Vol.19 (5), p.1083-1099

2021

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The renin-angiotensin-aldosterone system and its therapeutic targets

Experimental eye research, 2019-09, Vol.186, p.107680-107680, Article 107680

2019

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Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2013-03, Vol.65 (3), p.305-309

2013

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Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors

Organic & biomolecular chemistry, 2022-01, Vol.20 (3), p.619-629

2022

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Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses

Viruses, 2024-03, Vol.16 (3), p.388

2024

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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Journal of ethnopharmacology, 2010-01, Vol.127 (1), p.7-10

2010

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An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Journal of chemical information and modeling, 2023-12, Vol.63 (24), p.7699-7710

2023

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Rice bran protein hydrolysates exhibit strong in vitro α‐amylase, β‐glucosidase and ACE‐inhibition activities

Journal of the science of food and agriculture, 2016-03, Vol.96 (4), p.1101-1110

2016

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Renin-angiotensin system inhibitor exerts prognostic effects in HFpEF patients with low baseline chloride level

International journal of cardiology, 2023-02, Vol.373, p.83-89

2023

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Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis

Journal of Virology, 2006-07, Vol.80 (14), p.6964-6972

2006

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Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

Drug metabolism and disposition, 2017-09, Vol.45 (9), p.1035-1043

2017

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Need to continue or discontinue RAS inhibitors as CKD stage advances? Any alternative?

Hypertension research, 2023-08, Vol.46 (8), p.2048-2050

2023

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Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries

American journal of physiology. Heart and circulatory physiology, 2016-09, Vol.311 (3), p.H849-H854

2016

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What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

Toxicology letters, 2016-09, Vol.258, p.55-70

2016

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Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.8806-8817

2015

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Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema

British journal of pharmacology, 2008-03, Vol.153 (5), p.947-955

2008

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Increased risk of metastasis in patients with incidental use of renin-angiotensin system inhibitors: a retrospective analysis for multiple types of cancer based on electronic medical records

Hypertension research, 2022-12, Vol.45 (12), p.1869-1881

2022

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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

European journal of medicinal chemistry, 2014-10, Vol.85, p.418-437

2014

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Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

European journal of pharmaceutical sciences, 2015-06, Vol.73, p.49-56

2015

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Substance P Increases Sympathetic Activity During Combined Angiotensin-Converting Enzyme and Dipeptidyl Peptidase-4 Inhibition

Hypertension (Dallas, Tex. 1979), 2014-05, Vol.63 (5), p.951-957

2014

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8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

European journal of medicinal chemistry, 2016-11, Vol.124, p.1041-1056

2016

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Functionality of Bioactive Compounds in Brazilian Strawberry (Fragaria × ananassa Duch.) Cultivars: Evaluation of Hyperglycemia and Hypertension Potential Using in Vitro Models

Journal of agricultural and food chemistry, 2008-06, Vol.56 (12), p.4386-4392

2008

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Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Neuropharmacology, 2014-12, Vol.87, p.214-221

2014

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Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Clinical and experimental pharmacology & physiology, 2015-07, Vol.42 (7), p.795-807

2015

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A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors

The renin-angiotensin-aldosterone system and its therapeutic targets

Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors

Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses

Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Rice bran protein hydrolysates exhibit strong in vitro α‐amylase, β‐glucosidase and ACE‐inhibition activities

Renin-angiotensin system inhibitor exerts prognostic effects in HFpEF patients with low baseline chloride level

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis

Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

Need to continue or discontinue RAS inhibitors as CKD stage advances? Any alternative?

Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries

What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema

Increased risk of metastasis in patients with incidental use of renin-angiotensin system inhibitors: a retrospective analysis for multiple types of cancer based on electronic medical records

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

Substance P Increases Sympathetic Activity During Combined Angiotensin-Converting Enzyme and Dipeptidyl Peptidase-4 Inhibition

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

Functionality of Bioactive Compounds in Brazilian Strawberry (Fragaria × ananassa Duch.) Cultivars: Evaluation of Hyperglycemia and Hypertension Potential Using in Vitro Models

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

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