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A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

Chemical Society reviews, 2020-04, Vol.49 (8), p.2426-248

2020

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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Journal of medicinal chemistry, 2020-04, Vol.63 (7), p.3538-3551

2020

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Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma

PloS one, 2019-02, Vol.14 (2), p.e0212538-e0212538

2019

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Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12260-12265

2011

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Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

PloS one, 2019-03, Vol.14 (3), p.e0209392

2019

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Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis

Cell reports (Cambridge), 2017-01, Vol.18 (2), p.508-519

2017

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Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

PloS one, 2019-10, Vol.14 (10), p.e0224253

2019

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Inhibition of Carbohydrate Metabolism Potentiated by the Therapeutic Effects of Oxidative Phosphorylation Inhibitors in Colon Cancer Cells

Cancers, 2024-04, Vol.16 (7), p.1399

2024

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Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis

Acta biochimica et biophysica Sinica, 2016-01, Vol.48 (1), p.82-89

2016

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Advanced cardiac chemical exchange saturation transfer (cardioCEST) MRI for in vivo cell tracking and metabolic imaging

NMR in biomedicine, 2016-01, Vol.29 (1), p.74-83

2016

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Substances that can change alternative splice-site selection

Biochemical Society transactions, 2008-06, Vol.36 (Pt 3), p.483

2008

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Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

Cells (Basel, Switzerland), 2023-03, Vol.12 (7), p.1066

2023

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Functional Identification of Valerena-1,10-diene Synthase, a Terpene Synthase Catalyzing a Unique Chemical Cascade in the Biosynthesis of Biologically Active Sesquiterpenes in Valeriana officinalis

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3163-3173

2013

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Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

iScience, 2020-12, Vol.23 (12), p.101795-101795, Article 101795

2020

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New triaromatic steroids distinguish Paleozoic from Mesozoic oil

Organic geochemistry, 2011-05, Vol.42 (4), p.409-424

2011

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Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS)

Genomics (San Diego, Calif.), 2023-09, Vol.115 (5), p.110666-110666, Article 110666

2023

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Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells

Molecular cancer therapeutics, 2022-05, Vol.21 (5), p.740-750

2022

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Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis

Nature chemical biology, 2014-11, Vol.10 (11), p.924

2014

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An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11348-11358

2019

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Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

Molecular cancer therapeutics, 2021-10, Vol.20 (10), p.1893-1903

2021

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A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Molecular cancer therapeutics, 2021-12, Vol.20 (12), p.2398-2409

2021

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Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents

Journal of medicinal chemistry, 2021-08, Vol.64 (16), p.12152-12162

2021

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Broad‐Spectrum Antifungal Agents: Fluorinated Aryl‐ and Heteroaryl‐Substituted Hydrazones

ChemMedChem, 2021-01, Vol.16 (1), p.124-133

2021

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Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

Oncotarget, 2020-08, Vol.11 (31), p.3013-3024

2020

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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Organic & biomolecular chemistry, 2017-09, Vol.15 (36), p.7623-7629

2017

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A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma

Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii

Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis

Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

Inhibition of Carbohydrate Metabolism Potentiated by the Therapeutic Effects of Oxidative Phosphorylation Inhibitors in Colon Cancer Cells

Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis

Advanced cardiac chemical exchange saturation transfer (cardioCEST) MRI for in vivo cell tracking and metabolic imaging

Substances that can change alternative splice-site selection

Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

Functional Identification of Valerena-1,10-diene Synthase, a Terpene Synthase Catalyzing a Unique Chemical Cascade in the Biosynthesis of Biologically Active Sesquiterpenes in Valeriana officinalis

Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

New triaromatic steroids distinguish Paleozoic from Mesozoic oil

Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS)

Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells

Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis

An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors

Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents

Broad‐Spectrum Antifungal Agents: Fluorinated Aryl‐ and Heteroaryl‐Substituted Hydrazones

Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

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