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A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Human vaccines & immunotherapeutics, 2021-05, Vol.17 (5), p.1248-1261

2021

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Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination

Nature communications, 2016-01, Vol.7 (1), p.10369-10369, Article 10369

2016

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Quantification of clesrovimab, an investigational, half-life extended, anti-respiratory syncytial virus protein F human monoclonal antibody in the nasal epithelial lining fluid of healthy adults

Biomedicine & pharmacotherapy, 2023-12, Vol.169, p.115851-115851, Article 115851

2023

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Immune response and reactogenicity of intradermal administration versus subcutaneous administration of varicella-zoster virus vaccine: an exploratory, randomised, partly blinded trial

The Lancet infectious diseases, 2016-08, Vol.16 (8), p.915-922

2016

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Test-retest repeatability of MR elastography for noninvasive liver fibrosis assessment in hepatitis C

Journal of magnetic resonance imaging, 2011-10, Vol.34 (4), p.947-955

2011

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Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults

Vaccine, 2023-10, Vol.41 (44), p.6488-6501

2023

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Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis

EBioMedicine, 2021-11, Vol.73, p.103651-103651, Article 103651

2021

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Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines

Vaccines (Basel), 2023-09, Vol.11 (9), p.1501

2023

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A Phase 1 Randomized, Double‐Blind, Placebo‐Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK‐1654 in Healthy Adults

Clinical pharmacology in drug development, 2021-05, Vol.10 (5), p.556-566

2021

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Correlation between Circulating Fungal Biomarkers and Clinical Outcome in Invasive Aspergillosis

PloS one, 2015-06, Vol.10 (6), p.e0129022-e0129022

2015

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Early Clinical Detection of Pharmacologic Response in Insulin Action in a Nondiabetic Insulin-Resistant Population

Current therapeutic research, 2015-12, Vol.77 (C), p.83-89

2015

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Impact of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle vaccine in a sexually active population of North American women

American journal of obstetrics and gynecology, 2008-03, Vol.198 (3), p.261.e1-261.e11

2008

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Repeatability of edited lactate and other metabolites in astrocytoma at 3T

Journal of magnetic resonance imaging, 2012-08, Vol.36 (2), p.468-475

2012

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Quadrivalent Vaccine against Human Papillomavirus to Prevent Anogenital Diseases

The New England journal of medicine, 2007-05, Vol.356 (19), p.1928-1943

2007

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Minimum risk weights for comparing treatments in stratified binomial trials

Statistics in medicine, 2000-03, Vol.19 (6), p.811-825

2000

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“In‐House” Data on the Outside—A Mobile Health Approach

Clinical pharmacology and therapeutics, 2020-04, Vol.107 (4), p.948-956

2020

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Reproducibility of hepatic fat fraction measurement by magnetic resonance imaging

Journal of magnetic resonance imaging, 2013-06, Vol.37 (6), p.1359-1370

2013

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Bayesian methods for the design and analysis of noninferiority trials

Journal of biopharmaceutical statistics, 2016-09, Vol.26 (5), p.823-841

2016

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Fine‐Needle Aspiration for the Evaluation of Hepatic Pharmacokinetics of Vaniprevir: A Randomized Trial in Patients With Hepatitis C Virus Infection

Clinical pharmacology and therapeutics, 2020-06, Vol.107 (6), p.1325-1333

2020

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Impact of a Prophylactic Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) L1 Virus-Like Particle Vaccine in a Sexually Active Population of North American Women

Obstetrical & gynecological survey, 2008-06, Vol.63 (6), p.367-368

2008

Volltextzugriff (PDF)

1013. Predicting RSV Efficacy for MK-1654 in Temperate and Tropical Climates using MBMA and Clinical Trial Simulation to Account for Seasonal Differences in RSV Force-of-Infection

Open forum infectious diseases, 2021-12, Vol.8 (Supplement_1), p.S597-S598

2021

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Endogenous Serum IgG Antibodies to Clostridium difficile Toxin B Are Associated with Protection against C. difficile Infection Recurrence

Open forum infectious diseases, 2017-10, Vol.4 (suppl_1), p.S388-S388

2017

Volltextzugriff (PDF)

998. Forward and Reverse Translational Approaches to Predict Efficacy of the Neutralizing Respiratory Syncytial Virus (RSV) Antibody MK-1654

Open forum infectious diseases, 2021-12, Vol.8 (Supplement_1), p.S590-S590

2021

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A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination

Quantification of clesrovimab, an investigational, half-life extended, anti-respiratory syncytial virus protein F human monoclonal antibody in the nasal epithelial lining fluid of healthy adults

Immune response and reactogenicity of intradermal administration versus subcutaneous administration of varicella-zoster virus vaccine: an exploratory, randomised, partly blinded trial

Test-retest repeatability of MR elastography for noninvasive liver fibrosis assessment in hepatitis C

Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults

Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis

Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines

A Phase 1 Randomized, Double‐Blind, Placebo‐Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK‐1654 in Healthy Adults

Correlation between Circulating Fungal Biomarkers and Clinical Outcome in Invasive Aspergillosis

Early Clinical Detection of Pharmacologic Response in Insulin Action in a Nondiabetic Insulin-Resistant Population

Impact of a prophylactic quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle vaccine in a sexually active population of North American women

Repeatability of edited lactate and other metabolites in astrocytoma at 3T

Quadrivalent Vaccine against Human Papillomavirus to Prevent Anogenital Diseases

Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial

Minimum risk weights for comparing treatments in stratified binomial trials

“In‐House” Data on the Outside—A Mobile Health Approach

Immunologic responses following administration of a vaccine targeting human papillomavirus Types 6, 11, 16, and 18

Reproducibility of hepatic fat fraction measurement by magnetic resonance imaging

Bayesian methods for the design and analysis of noninferiority trials

Fine‐Needle Aspiration for the Evaluation of Hepatic Pharmacokinetics of Vaniprevir: A Randomized Trial in Patients With Hepatitis C Virus Infection

Impact of a Prophylactic Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) L1 Virus-Like Particle Vaccine in a Sexually Active Population of North American Women

1013. Predicting RSV Efficacy for MK-1654 in Temperate and Tropical Climates using MBMA and Clinical Trial Simulation to Account for Seasonal Differences in RSV Force-of-Infection

Endogenous Serum IgG Antibodies to Clostridium difficile Toxin B Are Associated with Protection against C. difficile Infection Recurrence

998. Forward and Reverse Translational Approaches to Predict Efficacy of the Neutralizing Respiratory Syncytial Virus (RSV) Antibody MK-1654

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