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Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-Scale Human Atrial Modeling

Frontiers in physiology, 2016-10, Vol.7, p.474-474

2016

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Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models

PLoS computational biology, 2016-12, Vol.12 (12), p.e1005245-e1005245

2016

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Image-Based Computational Evaluation of the Effects of Atrial Wall Thickness and Fibrosis on Re-entrant Drivers for Atrial Fibrillation

Frontiers in physiology, 2018-10, Vol.9, p.1352-1352

2018

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Interactions between calcium‐induced arrhythmia triggers and the electrophysiological–anatomical substrate underlying the induction of atrial fibrillation

The Journal of physiology, 2024-03, Vol.602 (5), p.835-853

2024

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Novel MRI Technique Enables Non-Invasive Measurement of Atrial Wall Thickness

IEEE transactions on medical imaging, 2017-08, Vol.36 (8), p.1607-1614

2017

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Patchy fibrosis promotes trigger–substrate interactions that both generate and maintain atrial fibrillation

Interface focus, 2023-12, Vol.13 (6)

2023

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Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria

The Journal of physiology, 2013-09, Vol.591 (17), p.4249-4272

2013

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Identifying locations of re-entrant drivers from patient-specific distribution of fibrosis in the left atrium

PLoS computational biology, 2020-09, Vol.16 (9), p.e1008086-e1008086

2020

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Novel Computational Analysis of Left Atrial Anatomy Improves Prediction of Atrial Fibrillation Recurrence after Ablation

Frontiers in physiology, 2017-02, Vol.8, p.68-68

2017

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Mathematical models of the electrical action potential of Purkinje fibre cells

Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2009-06, Vol.367 (1896), p.2225-2255

2009

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Mechanistic Links Between Na+ Channel (SCN5A) Mutations and Impaired Cardiac Pacemaking in Sick Sinus Syndrome

Circulation research, 2010-07, Vol.107 (1), p.126-137

2010

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Algorithms for left atrial wall segmentation and thickness – Evaluation on an open-source CT and MRI image database

Medical image analysis, 2018-12, Vol.50, p.36-53

2018

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Toward Patient-Specific Prediction of Ablation Strategies for Atrial Fibrillation Using Deep Learning

Frontiers in physiology, 2021-05, Vol.12, p.674106

2021

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Exploring interpretability in deep learning prediction of successful ablation therapy for atrial fibrillation

Frontiers in physiology, 2023-03, Vol.14, p.1054401

2023

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3D virtual human atria: A computational platform for studying clinical atrial fibrillation

Progress in biophysics and molecular biology, 2011-10, Vol.107 (1), p.156-168

2011

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Reinforcement Learning to Improve Image-Guidance of Ablation Therapy for Atrial Fibrillation

Frontiers in physiology, 2021-08, Vol.12, p.733139-733139

2021

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Application of Micro-Computed Tomography With Iodine Staining to Cardiac Imaging, Segmentation, and Computational Model Development

IEEE transactions on medical imaging, 2013-01, Vol.32 (1), p.8-17

2013

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Corrigendum: Reinforcement Learning to Improve Image-Guidance of Ablation Therapy for Atrial Fibrillation

Frontiers in physiology, 2021-11, Vol.12, p.799585-799585

2021

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Optimal Velocity and Safety of Discontinuous Conduction through the Heterogeneous Purkinje-Ventricular Junction

Biophysical journal, 2009-07, Vol.97 (1), p.20-39

2009

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Mechanisms of Transition from Normal to Reentrant Electrical Activity in a Model of Rabbit Atrial Tissue: Interaction of Tissue Heterogeneity and Anisotropy

Biophysical journal, 2009-02, Vol.96 (3), p.798-817

2009

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Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts

Scientific reports, 2020-09, Vol.10 (1), p.15284-15284, Article 15284

2020

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Computer Three‐Dimensional Anatomical Reconstruction of the Human Sinus Node and a Novel Paranodal Area

Anatomical record (Hoboken, N.J. : 2007), 2011-06, Vol.294 (6), p.970-979

2011

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A Mathematical Model of Neonatal Rat Atrial Monolayers with Constitutively Active Acetylcholine-Mediated K+ Current

PLoS computational biology, 2016-06, Vol.12 (6), p.e1004946-e1004946

2016

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Dynamical anchoring of distant arrhythmia sources by fibrotic regions via restructuring of the activation pattern

PLoS computational biology, 2018-12, Vol.14 (12), p.e1006637-e1006637

2018

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Initiation and sustenance of reentry are promoted by two different mechanisms

Heart rhythm, 2015-01, Vol.12 (1), p.e2-e2

2015

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Animals
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Humans
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Cardiovascular System & Cardiology
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Fibrosis
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Cardiac Arrhythmia
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Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-Scale Human Atrial Modeling

Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models

Image-Based Computational Evaluation of the Effects of Atrial Wall Thickness and Fibrosis on Re-entrant Drivers for Atrial Fibrillation

Interactions between calcium‐induced arrhythmia triggers and the electrophysiological–anatomical substrate underlying the induction of atrial fibrillation

Novel MRI Technique Enables Non-Invasive Measurement of Atrial Wall Thickness

Patchy fibrosis promotes trigger–substrate interactions that both generate and maintain atrial fibrillation

Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria

Identifying locations of re-entrant drivers from patient-specific distribution of fibrosis in the left atrium

Novel Computational Analysis of Left Atrial Anatomy Improves Prediction of Atrial Fibrillation Recurrence after Ablation

Mathematical models of the electrical action potential of Purkinje fibre cells

Mechanistic Links Between Na+ Channel (SCN5A) Mutations and Impaired Cardiac Pacemaking in Sick Sinus Syndrome

Algorithms for left atrial wall segmentation and thickness – Evaluation on an open-source CT and MRI image database

Toward Patient-Specific Prediction of Ablation Strategies for Atrial Fibrillation Using Deep Learning

Exploring interpretability in deep learning prediction of successful ablation therapy for atrial fibrillation

3D virtual human atria: A computational platform for studying clinical atrial fibrillation

Reinforcement Learning to Improve Image-Guidance of Ablation Therapy for Atrial Fibrillation

Application of Micro-Computed Tomography With Iodine Staining to Cardiac Imaging, Segmentation, and Computational Model Development

Corrigendum: Reinforcement Learning to Improve Image-Guidance of Ablation Therapy for Atrial Fibrillation

Optimal Velocity and Safety of Discontinuous Conduction through the Heterogeneous Purkinje-Ventricular Junction

Mechanisms of Transition from Normal to Reentrant Electrical Activity in a Model of Rabbit Atrial Tissue: Interaction of Tissue Heterogeneity and Anisotropy

Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts

Computer Three‐Dimensional Anatomical Reconstruction of the Human Sinus Node and a Novel Paranodal Area

A Mathematical Model of Neonatal Rat Atrial Monolayers with Constitutively Active Acetylcholine-Mediated K+ Current

Dynamical anchoring of distant arrhythmia sources by fibrotic regions via restructuring of the activation pattern

Initiation and sustenance of reentry are promoted by two different mechanisms

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