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Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.66-75

2017

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Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

International journal of clinical pharmacology and therapeutics, 2016-08, Vol.54 (8), p.572-580

2016

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No Dose Adjustment for Isavuconazole Based on Age or Sex

Antimicrobial agents and chemotherapy, 2019-06, Vol.63 (6)

2019

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Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2007-03, Vol.320 (3), p.1087-1096

2007

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Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.44-53

2017

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Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.76-85

2017

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AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes

Biochemical and biophysical research communications, 2010-10, Vol.400 (4), p.745-751

2010

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Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion

The Journal of pharmacology and experimental therapeutics, 2013-09, Vol.346 (3), p.443-452

2013

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Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.86-92

2017

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ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: preclinical investigation and a Phase I study in advanced solid tumors

Cancer chemotherapy and pharmacology, 2016-03, Vol.77 (3), p.549-558

2016

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Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.93-101

2017

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Comparison of the Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Healthy Japanese and Caucasian Subjects

Clinical drug investigation, 2015-06, Vol.35 (6), p.375-384

2015

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Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects

Clinical pharmacology in drug development, 2017-01, Vol.6 (1), p.54-65

2017

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A Multicenter Prospective Observational Cohort Study to Investigate the Effectiveness and Safety of Rivaroxaban in Japanese Venous Thromboembolism Patients (The J’xactly Study)

Circulation Journal, 2020/10/23, Vol.84(11), pp.1912-1921

2020

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Prediction model for 3-year rupture risk of unruptured cerebral aneurysms in Japanese patients

Annals of neurology, 2015-06, Vol.77 (6), p.1050-1059

2015

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High Prevalence of Obesity, Hypertension, Hyperlipidemia, and Diabetes Mellitus in Japanese Outpatients with Schizophrenia: A Nationwide Survey

PloS one, 2016-11, Vol.11 (11), p.e0166429-e0166429

2016

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Optimal Treatment Strategy for Patients With Paroxysmal Atrial Fibrillation: J-RHYTHM Study

Circulation Journal, 2009, Vol.73(2), pp.242-248

2009

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High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD): A Randomized Superiority Trial

Circulation (New York, N.Y.), 2018-05, Vol.137 (19), p.1997-2009

2018

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The clinical course of patients with IgG4-related kidney disease

Kidney international, 2013-10, Vol.84 (4), p.826-833

2013

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Early Stage of Progressive Supranuclear Palsy: A Neuropathological Study of 324 Consecutive Autopsy Cases

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2015, Vol.82 (6), p.266-273

2015

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Survivin: A novel marker and potential therapeutic target for human angiosarcoma

Cancer science, 2017-11, Vol.108 (11), p.2295-2305

2017

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Correlation between Serum Resistin Level and Adiposity in Obese Individuals

Obesity (Silver Spring, Md.), 2003-08, Vol.11 (8), p.997-1001

2003

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Risk for malignancy in rheumatoid arthritis patients treated with biological disease-modifying antirheumatic drugs compared to the general population: A nationwide cohort study in Japan

Modern rheumatology, 2016-09, Vol.26 (5), p.642-650

2016

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Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex

Neuroscience research, 2007-10, Vol.59 (2), p.160-171

2007

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Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects

Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

No Dose Adjustment for Isavuconazole Based on Age or Sex

Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo

Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults

Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes

Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion

Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: preclinical investigation and a Phase I study in advanced solid tumors

Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

Comparison of the Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Healthy Japanese and Caucasian Subjects

Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects

A Multicenter Prospective Observational Cohort Study to Investigate the Effectiveness and Safety of Rivaroxaban in Japanese Venous Thromboembolism Patients (The J’xactly Study)

Prediction model for 3-year rupture risk of unruptured cerebral aneurysms in Japanese patients

Sex Difference and Rupture Rate of Intracranial Aneurysms: An Individual Patient Data Meta-Analysis

High Prevalence of Obesity, Hypertension, Hyperlipidemia, and Diabetes Mellitus in Japanese Outpatients with Schizophrenia: A Nationwide Survey

Optimal Treatment Strategy for Patients With Paroxysmal Atrial Fibrillation: J-RHYTHM Study

High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD): A Randomized Superiority Trial

The clinical course of patients with IgG4-related kidney disease

Early Stage of Progressive Supranuclear Palsy: A Neuropathological Study of 324 Consecutive Autopsy Cases

Survivin: A novel marker and potential therapeutic target for human angiosarcoma

Correlation between Serum Resistin Level and Adiposity in Obese Individuals

Risk for malignancy in rheumatoid arthritis patients treated with biological disease-modifying antirheumatic drugs compared to the general population: A nationwide cohort study in Japan

Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex

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