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A calcineurin antifungal strategy with analogs of FK506

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2465-2471

2017

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A new family of H3 receptor antagonists based on the natural product Conessine

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1490-1494

2008

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Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1

Bioorganic & medicinal chemistry letters, 2002-04, Vol.12 (7), p.1063-1066

2002

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Discovery and Structure−Activity Relationship of 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine2A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis

Journal of medicinal chemistry, 2010-06, Vol.53 (11), p.4412-4421

2010

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Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.1923-1936

2010

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Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1467-1470

2005

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Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5486-5489

2009

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Preparation and biological activity of novel tricyclic GPIIb/IIIa antagonists

Bioorganic & medicinal chemistry, 1998-12, Vol.6 (12), p.2345-2381

1998

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Synthesis of 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]butane and 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]but-2-ene, novel heterobifunctional cross-linking reagents

Bioconjugate chemistry, 1990-03, Vol.1 (2), p.96-99

1990

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Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care

The New England journal of medicine, 2012-11, Vol.367 (20), p.1901-1911

2012

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Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients

The New England journal of medicine, 2022-01, Vol.386 (4), p.305-315

2022

Volltextzugriff (PDF)

Colour as a signal for entraining the mammalian circadian clock

PLoS biology, 2015-04, Vol.13 (4), p.e1002127-e1002127

2015

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Dysfunctional HDL and atherosclerotic cardiovascular disease

Nature reviews cardiology, 2016-01, Vol.13 (1), p.48

2016

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5-Year Outcome After Transcatheter Aortic Valve Implantation

Journal of the American College of Cardiology, 2013-01, Vol.61 (4), p.413-419

2013

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Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement

The New England journal of medicine, 2020-02, Vol.382 (9), p.799-809

2020

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Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis

The New England journal of medicine, 2012-05, Vol.366 (18), p.1696-1704

2012

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Informed Consent in Decision-Making in Pediatric Practice

Pediatrics (Evanston), 2016-08, Vol.138 (2)

COMMITTEE ON BIOETHICS

2016

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Long-term health conditions and UK labour market outcomes during the COVID-19 pandemic

PloS one, 2024-05, Vol.19 (5), p.e0302746-e0302746

2024

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Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients

The New England journal of medicine, 2016-04, Vol.374 (17), p.1609-1620

2016

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Meta-Analysis of the Impact of Mitral Regurgitation on Outcomes After Transcatheter Aortic Valve Implantation

The American journal of cardiology, 2015-04, Vol.115 (7), p.942-949

2015

Volltextzugriff (PDF)

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012

Critical care medicine, 2013-02, Vol.41 (2), p.580-637

2013

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Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging

Nature immunology, 2023-07, Vol.24 (7), p.1124

2023

Volltextzugriff (PDF)

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

Intensive care medicine, 2013-02, Vol.39 (2), p.165-228

2013

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A calcineurin antifungal strategy with analogs of FK506

A new family of H3 receptor antagonists based on the natural product Conessine

Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2C Receptor Agonist for the Treatment of Obesity

Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1

Discovery and Structure−Activity Relationship of 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine2A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis

Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia

Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity

Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents

Preparation and biological activity of novel tricyclic GPIIb/IIIa antagonists

Synthesis of 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]butane and 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]but-2-ene, novel heterobifunctional cross-linking reagents

Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care

Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients

Colour as a signal for entraining the mammalian circadian clock

Dysfunctional HDL and atherosclerotic cardiovascular disease

5-Year Outcome After Transcatheter Aortic Valve Implantation

Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement

Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis

Informed Consent in Decision-Making in Pediatric Practice

Long-term health conditions and UK labour market outcomes during the COVID-19 pandemic

Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients

Meta-Analysis of the Impact of Mitral Regurgitation on Outcomes After Transcatheter Aortic Valve Implantation

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012

Orteronel plus prednisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4): a double-blind, multicentre, phase 3, randomised, placebo-controlled trial

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

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