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Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.3852-3865

2023

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Structural basis for GPR40 allosteric agonism and incretin stimulation

Nature communications, 2018-04, Vol.9 (1), p.1645-11, Article 1645

2018

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RV-GAN: Segmenting Retinal Vascular Structure in Fundus Photographs Using a Novel Multi-scale Generative Adversarial Network

Medical Image Computing and Computer Assisted Intervention – MICCAI 2021, 2021, p.34-44

2021

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Changes in interstitial cells and gastric excitability in a mouse model of sleeve gastrectomy

PloS one, 2022-06, Vol.17 (6), p.e0269909-e0269909

2022

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Secretin Inhibits Small Intestinal Motility via Interstitial Cells of Cajal and cAMP Mechanisms

Physiology (Bethesda, Md.), 2024-05, Vol.39 (S1)

2024

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Temporal sequence of activation of cells involved in purinergic neurotransmission in the colon

The Journal of physiology, 2015-04, Vol.593 (8), p.1945-1963

2015

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Interstitial cells of the sip syncytium regulate basal membrane potential in murine gastric corpus

The FASEB journal, 2024-08, Vol.38 (16), p.e23863-n/a

2024

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A novel postsynaptic signal pathway of sympathetic neural regulation of murine colonic motility

The FASEB journal, 2020-04, Vol.34 (4), p.5563-5577

2020

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Ca 2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract

Physiological reviews, 2024-01, Vol.104 (1), p.329-398

2024

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A high throughput machine-learning driven analysis of Ca2+ spatio-temporal maps

Cell calcium (Edinburgh), 2020-11, Vol.91, p.102260-102260, Article 102260

2020

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[(H2O)Zn(Imidazole)n]2+: the vital roles of coordination number and geometry in Zn–OH2 acidity and catalytic hydrolysis

Physical chemistry chemical physics : PCCP, 2018-01, Vol.20 (38), p.24979-24991

2018

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Spontaneous Ca(2+) transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine

The Journal of physiology, 2016-06, Vol.594 (12), p.3317-3338

2016

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Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking

Cell calcium (Edinburgh), 2021-11, Vol.99, p.102472-102472, Article 102472

2021

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Spontaneous Ca2+ transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine

The Journal of physiology, 2016-06, Vol.594 (12), p.3317-3338

2016

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Distribution and Ca(2+) signalling of fibroblast-like (PDGFR(+)) cells in the murine gastric fundus

The Journal of physiology, 2013-12, Vol.591 (24), p.6193-6208

2013

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Calcium transients in intramuscular interstitial cells of Cajal of the murine gastric fundus and their regulation by neuroeffector transmission

The Journal of physiology, 2022-10, Vol.600 (20), p.4439-4463

2022

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Distribution and Ca2+ signalling of fibroblast‐like (PDGFRα+) cells in the murine gastric fundus

The Journal of physiology, 2013-12, Vol.591 (24), p.6193-6208

2013

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Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca 2+ release via M 3 receptor activation

The FASEB journal, 2020-08, Vol.34 (8), p.10073-10095

2020

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Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca2+ release via M3 receptor activation

The FASEB journal, 2020-08, Vol.34 (8), p.10073-10095

2020

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[(H 2 O)Zn(Imidazole) n ] 2+ : the vital roles of coordination number and geometry in Zn-OH 2 acidity and catalytic hydrolysis

Physical chemistry chemical physics : PCCP, 2018-10, Vol.20 (38), p.24979-24991

2018

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Ca2+ Signaling Is the Basis for Pacemaker Activity and Neurotransduction in Interstitial Cells of the GI Tract

The Enteric Nervous System II, 2023, Vol.1383, p.229-241

2023

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Ca 2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters

The Journal of physiology, 2022-06, Vol.600 (11), p.2613-2636

2022

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Applications of Spatio-temporal Mapping and Particle Analysis Techniques to Quantify Intracellular Ca2+ Signaling In Situ

Journal of visualized experiments, 2019-01 (143)

2019

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Retropubic versus Transobturator Midurethral Slings for Stress Incontinence

The New England journal of medicine, 2010-06, Vol.362 (22), p.2066-2076

2010

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The effects of mitochondrial inhibitors on Ca2+ signalling and electrical conductances required for pacemaking in interstitial cells of Cajal in the mouse small intestine

Cell calcium (Edinburgh), 2018-06, Vol.72, p.1-17

2018

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Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo

Structural basis for GPR40 allosteric agonism and incretin stimulation

RV-GAN: Segmenting Retinal Vascular Structure in Fundus Photographs Using a Novel Multi-scale Generative Adversarial Network

Changes in interstitial cells and gastric excitability in a mouse model of sleeve gastrectomy

Secretin Inhibits Small Intestinal Motility via Interstitial Cells of Cajal and cAMP Mechanisms

Temporal sequence of activation of cells involved in purinergic neurotransmission in the colon

Interstitial cells of the sip syncytium regulate basal membrane potential in murine gastric corpus

A novel postsynaptic signal pathway of sympathetic neural regulation of murine colonic motility

Ca 2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract

A high throughput machine-learning driven analysis of Ca2+ spatio-temporal maps

[(H2O)Zn(Imidazole)n]2+: the vital roles of coordination number and geometry in Zn–OH2 acidity and catalytic hydrolysis

Spontaneous Ca(2+) transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine

Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking

Spontaneous Ca2+ transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine

Distribution and Ca(2+) signalling of fibroblast-like (PDGFR(+)) cells in the murine gastric fundus

Calcium transients in intramuscular interstitial cells of Cajal of the murine gastric fundus and their regulation by neuroeffector transmission

Distribution and Ca2+ signalling of fibroblast‐like (PDGFRα+) cells in the murine gastric fundus

Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca 2+ release via M 3 receptor activation

Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca2+ release via M3 receptor activation

[(H 2 O)Zn(Imidazole) n ] 2+ : the vital roles of coordination number and geometry in Zn-OH 2 acidity and catalytic hydrolysis

Ca2+ Signaling Is the Basis for Pacemaker Activity and Neurotransduction in Interstitial Cells of the GI Tract

Ca 2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters

Applications of Spatio-temporal Mapping and Particle Analysis Techniques to Quantify Intracellular Ca2+ Signaling In Situ

Retropubic versus Transobturator Midurethral Slings for Stress Incontinence

The effects of mitochondrial inhibitors on Ca2+ signalling and electrical conductances required for pacemaking in interstitial cells of Cajal in the mouse small intestine

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