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Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Clinical cancer research, 2006-09, Vol.12 (17), p.5064-5073

2006

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Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Molecular cancer therapeutics, 2005-01, Vol.4 (1), p.101-112

2005

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Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft

Molecular cancer therapeutics, 2005-09, Vol.4 (9), p.1364-1368

2005

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Nature, 2006-12, Vol.444 (7120), p.756-760

2006

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Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII‐specific scFv

International journal of cancer, 2000-12, Vol.88 (6), p.962-969

2000

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Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors

Anti-cancer agents in medicinal chemistry, 2011-02, Vol.11 (2), p.202

2011

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Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate

Nuclear medicine and biology, 2002, Vol.29 (1), p.1-11

2002

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Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice

Cancer chemotherapy and pharmacology, 2001-11, Vol.48 (5), p.413-416

2001

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Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

Cancer chemotherapy and pharmacology, 1994, Vol.34 (2), p.171-174

1994

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In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line

Glycoconjugate journal, 1996-06, Vol.13 (3), p.391-399

1996

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Therapeutic activity of the topoisomerase I inhibitor J-107088 [6-N-(1-hydroxymethyla-2-hydroxy) ethylamino-12,13-dihydro-13-(β-d-gluco pyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]-carbazole-5,7(6h)-dione] against pediatric and adult central nervous system tumor xenografts

Cancer chemotherapy and pharmacology, 2001-09, Vol.48 (3), p.250-254

2001

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Therapeutic activity of 7-[(2-trimethylsilyl)ethyl]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice

Cancer chemotherapy and pharmacology, 2001-07, Vol.48 (1), p.83-87

2001

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Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model

Clinical cancer research, 1997-01, Vol.3 (1), p.63-70

1997

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Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro

Molecular and chemical neuropathology, 1994-02, Vol.21 (2-3), p.129-138

1994

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Labeling Monoclonal Antibodies and F(ab′)2 Fragments with the α -Particle-Emitting Nuclide Astatine-211: Preservation of Immunoreactivity and in vivo Localizing Capacity

Proceedings of the National Academy of Sciences - PNAS, 1989-09, Vol.86 (18), p.7149-7153

1989

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Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents

Cancer chemotherapy and pharmacology, 1998, Vol.41 (6), p.485-490

1998

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Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an α-particle-emitting immunoconjugate

Nuclear medicine and biology, 1997-04, Vol.24 (3), p.255-261

1997

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Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts

Cancer chemotherapy and pharmacology, 2000, Vol.45 (4), p.345-349

2000

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O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts

Journal of neurosurgery, 1989-04, Vol.70 (4), p.573-577

1989

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Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc

The American journal of pathology, 1988-03, Vol.130 (3), p.472-484

1988

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In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: Comparison with its murine parent

Nuclear medicine and biology, 1997-10, Vol.24 (7), p.639-647

1997

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Fluorine-18-Labeled Monoclonal Antibody Fragments: A Potential Approach for Combining Radioimmunoscintigraphy and Positron Emission Tomography

The Journal of nuclear medicine (1978), 1992-08, Vol.33 (8), p.1535-1541

1992

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Intrathecal Administration of Single-Chain Immunotoxin, LMB-7 [B3(Fv)- PE38], Produces Cures of Carcinomatous Meningitis in a Rat Model

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (7), p.2765-2769

1995

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Medulloblastoma : tumor biological and clinical perspectives

Journal of neuro-oncology, 1991-08, Vol.11 (1), p.1-15

1991

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Chimeric anti-tenascin antibody 81C6: Increased tumor localization compared with its murine parent

Nuclear medicine and biology, 1996-05, Vol.23 (4), p.449-458

1996

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Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII‐specific scFv

Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors

Improved xenograft targeting of tumor-specific anti-epidermal growth factor receptor variant III antibody labeled using N-succinimidyl 4-guanidinomethyl-3-iodobenzoate

Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice

Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line

Therapeutic activity of the topoisomerase I inhibitor J-107088 [6-N-(1-hydroxymethyla-2-hydroxy) ethylamino-12,13-dihydro-13-(β-d-gluco pyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]-carbazole-5,7(6h)-dione] against pediatric and adult central nervous system tumor xenografts

Therapeutic activity of 7-[(2-trimethylsilyl)ethyl]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice

Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model

Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro

Labeling Monoclonal Antibodies and F(ab′)2 Fragments with the α -Particle-Emitting Nuclide Astatine-211: Preservation of Immunoreactivity and in vivo Localizing Capacity

Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents

Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an α-particle-emitting immunoconjugate

Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts

O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts

Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc

In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: Comparison with its murine parent

Fluorine-18-Labeled Monoclonal Antibody Fragments: A Potential Approach for Combining Radioimmunoscintigraphy and Positron Emission Tomography

Intrathecal Administration of Single-Chain Immunotoxin, LMB-7 [B3(Fv)- PE38], Produces Cures of Carcinomatous Meningitis in a Rat Model

Medulloblastoma : tumor biological and clinical perspectives

Chimeric anti-tenascin antibody 81C6: Increased tumor localization compared with its murine parent

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