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Enzybiotics: Enzyme-Based Antibacterials as Therapeutics

Advances in experimental medicine and biology, 2019-01, Vol.1148, p.233-253

2019

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Phage Lytic Enzymes

Viruses, 2019-01, Vol.11 (2), p.113

Briers, Yves

2019

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Predicting bacteriophage hosts based on sequences of annotated receptor-binding proteins

Scientific reports, 2021-01, Vol.11 (1), p.1467-1467, Article 1467

2021

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The Preclinical and Clinical Progress of Bacteriophages and Their Lytic Enzymes: The Parts are Easier than the Whole

Viruses, 2019-01, Vol.11 (2), p.96

2019

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Modeling the Architecture of Depolymerase-Containing Receptor Binding Proteins in Klebsiella Phages

Frontiers in microbiology, 2019-11, Vol.10, p.2649-2649

2019

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Phage tailspike modularity and horizontal gene transfer reveals specificity towards E. coli O-antigen serogroups

Virology journal, 2023-08, Vol.20 (1), p.174-174, Article 174

2023

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What's in a Name? An Overview of the Proliferating Nomenclature in the Field of Phage Lysins

Cells (Basel, Switzerland), 2023-08, Vol.12 (15), p.2016

2023

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Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms

Frontiers in microbiology, 2018-10, Vol.9, p.2517-2517

2018

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Exploiting phage receptor binding proteins to enable endolysins to kill Gram-negative bacteria

Scientific reports, 2020-07, Vol.10 (1), p.12087-12087, Article 12087

2020

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Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

Antimicrobial agents and chemotherapy, 2014-07, Vol.58 (7), p.3774-3784

2014

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Engineered endolysin-based "Artilysins" to combat multidrug-resistant gram-negative pathogens

mBio, 2014-07, Vol.5 (4), p.e01379-e01314

2014

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Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

Antimicrobial agents and chemotherapy, 2016-06, Vol.60 (6), p.3480-3488

2016

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Identification of Phage Receptor-Binding Protein Sequences with Hidden Markov Models and an Extreme Gradient Boosting Classifier

Viruses, 2022-06, Vol.14 (6), p.1329

2022

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DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models

PLoS computational biology, 2024-08, Vol.20 (8), p.e1011831

2024

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PhaLP: A Database for the Study of Phage Lytic Proteins and Their Evolution

Viruses, 2021-06, Vol.13 (7), p.1240

2021

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Inhibitory and bactericidal effect of Artilysin® Art-175 against colistin-resistant mcr-1-positive Escherichia coli isolates

International journal of antimicrobial agents, 2018-03, Vol.51 (3), p.528-529

2018

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Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity

mBio, 2021-05, Vol.12 (3)

2021

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Synergistic action of phage phiIPLA-RODI and lytic protein CHAPSH3b: a combination strategy to target Staphylococcus aureus biofilms

NPJ biofilms and microbiomes, 2021-04, Vol.7 (1), p.39-10, Article 39

2021

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Crowdsourced mapping of unexplored target space of kinase inhibitors

Nature communications, 2021-06, Vol.12 (1), p.3307-18, Article 3307

2021

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Phage lysins for intestinal microbiome modulation: current challenges and enabling techniques

Gut microbes, 2024-12, Vol.16 (1), p.2387144

2024

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Prediction of Klebsiella phage-host specificity at the strain level

Nature communications, 2024-05, Vol.15 (1), p.4355-4355, Article 4355

2024

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SEVAtile: a standardised DNA assembly method optimised for Pseudomonas

Microbial biotechnology, 2022-01, Vol.15 (1), p.370-386

2022

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High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

Nature communications, 2022-11, Vol.13 (1), p.7241-7241, Article 7241

2022

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Quality control and statistical evaluation of combinatorial DNA libraries using nanopore sequencing

BioTechniques, 2020-11, Vol.69 (5), p.379-383

2020

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A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections

Scientific reports, 2016-06, Vol.6 (1), p.28115-28115, Article 28115

2016

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Enzybiotics: Enzyme-Based Antibacterials as Therapeutics

Phage Lytic Enzymes

Predicting bacteriophage hosts based on sequences of annotated receptor-binding proteins

The Preclinical and Clinical Progress of Bacteriophages and Their Lytic Enzymes: The Parts are Easier than the Whole

Modeling the Architecture of Depolymerase-Containing Receptor Binding Proteins in Klebsiella Phages

Phage tailspike modularity and horizontal gene transfer reveals specificity towards E. coli O-antigen serogroups

What's in a Name? An Overview of the Proliferating Nomenclature in the Field of Phage Lysins

Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms

Exploiting phage receptor binding proteins to enable endolysins to kill Gram-negative bacteria

Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

Engineered endolysin-based "Artilysins" to combat multidrug-resistant gram-negative pathogens

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

Identification of Phage Receptor-Binding Protein Sequences with Hidden Markov Models and an Extreme Gradient Boosting Classifier

DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models

PhaLP: A Database for the Study of Phage Lytic Proteins and Their Evolution

Inhibitory and bactericidal effect of Artilysin® Art-175 against colistin-resistant mcr-1-positive Escherichia coli isolates

Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity

Synergistic action of phage phiIPLA-RODI and lytic protein CHAPSH3b: a combination strategy to target Staphylococcus aureus biofilms

Crowdsourced mapping of unexplored target space of kinase inhibitors

Phage lysins for intestinal microbiome modulation: current challenges and enabling techniques

Prediction of Klebsiella phage-host specificity at the strain level

SEVAtile: a standardised DNA assembly method optimised for Pseudomonas

High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

Quality control and statistical evaluation of combinatorial DNA libraries using nanopore sequencing

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections

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