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Does Huntingtin play a role in selective macroautophagy?

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3401-3413

Steffan, Joan S.

2010

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PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo

Neuron (Cambridge, Mass.), 2016-05, Vol.90 (3), p.507-520

2016

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Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

Neuron (Cambridge, Mass.), 2009-12, Vol.64 (6), p.828-840

2009

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Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

The Journal of neuroscience, 2008-11, Vol.28 (45), p.11500-11510

2008

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SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

Cell reports (Cambridge), 2013-07, Vol.4 (2), p.362-375

2013

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Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8914

2021

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Serine 421 regulates mutant huntingtin toxicity and clearance in mice

The Journal of clinical investigation, 2016-09, Vol.126 (9), p.3585-3597

2016

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A cause for childhood ataxia

eLife, 2016-03, Vol.5

Steffan, Joan S

2016

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Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

Stem cell reports, 2018-01, Vol.10 (1), p.58-72

2018

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Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Experimental neurology, 2021-04, Vol.338, p.113463, Article 113463

2021

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Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

Journal of cell science, 2022-01, Vol.135 (2)

2022

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

The Journal of cell biology, 2009-12, Vol.187 (7), p.1083-1099

2009

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Phosphorylation of Threonine 3: IMPLICATIONS FOR HUNTINGTIN AGGREGATION AND NEUROTOXICITY

The Journal of biological chemistry, 2009-10, Vol.284 (43), p.29427-29436

2009

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Journal of Huntington's disease, 2022-01, Vol.11 (1), p.25-33

2022

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Autophagy researchers

Autophagy, 2014-02, Vol.10 (2), p.188-191

2014

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Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Stem cells translational medicine, 2017-06, Vol.6 (6), p.1477-1490

2017

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Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Journal of Huntington's disease, 2018-01, Vol.7 (2), p.137-150

2018

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A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

Nature genetics, 2002-04, Vol.30 (4), p.367-376

2002

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Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

Journal of Huntington's disease, 2018-01, Vol.7 (4), p.321-335

2018

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Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Journal of Huntington's disease, 2012, Vol.1 (1), p.71-87

2012

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Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

Expert opinion on therapeutic targets, 2003-04, Vol.7 (2), p.201-213

2003

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RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

The Journal of biological chemistry, 1996-08, Vol.271 (35), p.21062-21067

1996

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Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Biochemistry (Easton), 1988-11, Vol.27 (22), p.8393-8400

1988

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Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3752-3761

1998

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Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (36), p.21220-21225

1995

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Does Huntingtin play a role in selective macroautophagy?

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo

Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

Serine 421 regulates mutant huntingtin toxicity and clearance in mice

A cause for childhood ataxia

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Phosphorylation of Threonine 3: IMPLICATIONS FOR HUNTINGTIN AGGREGATION AND NEUROTOXICITY

Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Autophagy researchers

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I

Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Expression and Function of a Mislocalized Form of Peroxisomal Malate Dehydrogenase (MDH3) in Yeast (∗)

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