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Brain macrophages harbor latent, infectious simian immunodeficiency virus

AIDS (London), 2019-12, Vol.33 Suppl 2 (Supplement 2), p.S181-S188

2019

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Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

PLoS pathogens, 2019-07, Vol.15 (7), p.e1007869

2019

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Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006871

2018

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Quantitative and Qualitative Distinctions between HIV-1 and SIV Reservoirs: Implications for HIV-1 Cure-Related Studies

Viruses, 2024-04, Vol.16 (4), p.514

Mudd, Joseph C

2024

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CCR5 as a Treatment Target in Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2014-09, Vol.130 (11), p.880-891

2014

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Glycerol Monolaurate Microbicide Protection against Repeat High-Dose SIV Vaginal Challenge

PloS one, 2015-06, Vol.10 (6), p.e0129465-e0129465

2015

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Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques

Retrovirology, 2023-08, Vol.20 (1), p.13-10, Article 13

2023

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Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)

PloS one, 2018-02, Vol.13 (2), p.e0190908-e0190908

2018

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In vitro effects of the small-molecule protein kinase C agonists on HIV latency reactivation

Scientific reports, 2016-12, Vol.6 (1), p.39032-39032, Article 39032

2016

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Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline

PloS one, 2014-04, Vol.9 (4), p.e94375

2014

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Residual viremia in an RT-SHIV rhesus macaque HAART model marked by the presence of a predominant plasma clone and a lack of viral evolution

PloS one, 2014-02, Vol.9 (2), p.e88258-e88258

2014

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Chronic delta-9-tetrahydrocannabinol (THC) treatment counteracts SIV-induced modulation of proinflammatory microRNA cargo in basal ganglia-derived extracellular vesicles

Journal of neuroinflammation, 2022-09, Vol.19 (1), p.225-225, Article 225

2022

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CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

Frontiers in immunology, 2021-11, Vol.12, p.794638-794638

2021

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Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

Journal of translational medicine, 2016-05, Vol.14 (1), p.148-148, Article 148

2016

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Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161 + CD8 + T Cells in SIV-Infected Rhesus Macaques

Viruses, 2023-09, Vol.15 (9), p.1944

2023

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IL-7 Induces Immunological Improvement in SIV-Infected Rhesus Macaques under Antiviral Therapy

Journal of Immunology, 2006-01, Vol.176 (2), p.914-922

2006

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Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS

PloS one, 2010-05, Vol.5 (5), p.e10523-e10523

2010

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SIV Infection Is Associated with Transient Acute-Phase Steatosis in Hepatocytes In Vivo

Viruses, 2024-02, Vol.16 (2), p.296

2024

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Treatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaques

PLoS pathogens, 2012-04, Vol.8 (4), p.e1002636-e1002636

2012

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A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use

AIDS research and human retroviruses, 2012-11, Vol.28 (11), p.1476-1484

2012

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Nonhuman primate models for HIV cure research

PLoS pathogens, 2012-08, Vol.8 (8), p.e1002892-e1002892

2012

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Mucosal Topical Microbicide Candidates Exert Influence on the Subsequent SIV Infection and Survival by Regulating SIV-Specific T-Cell Immune Responses

Journal of acquired immune deficiency syndromes (1999), 2016-02, Vol.71 (2), p.121-129

2016

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SIV Coreceptor Specificity in Natural and Non-Natural Host Infection: Implications for Cell Targeting and Differential Outcomes from Infection

Current HIV research, 2018-01, Vol.16 (1), p.41-51

2018

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A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants

PloS one, 2014-09, Vol.9 (9), p.e108109

2014

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

Brain macrophages harbor latent, infectious simian immunodeficiency virus

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART

Quantitative and Qualitative Distinctions between HIV-1 and SIV Reservoirs: Implications for HIV-1 Cure-Related Studies

CCR5 as a Treatment Target in Pulmonary Arterial Hypertension

Glycerol Monolaurate Microbicide Protection against Repeat High-Dose SIV Vaginal Challenge

Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques

Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)

In vitro effects of the small-molecule protein kinase C agonists on HIV latency reactivation

Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline

Residual viremia in an RT-SHIV rhesus macaque HAART model marked by the presence of a predominant plasma clone and a lack of viral evolution

Chronic delta-9-tetrahydrocannabinol (THC) treatment counteracts SIV-induced modulation of proinflammatory microRNA cargo in basal ganglia-derived extracellular vesicles

CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161 + CD8 + T Cells in SIV-Infected Rhesus Macaques

IL-7 Induces Immunological Improvement in SIV-Infected Rhesus Macaques under Antiviral Therapy

Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS

SIV Infection Is Associated with Transient Acute-Phase Steatosis in Hepatocytes In Vivo

Treatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaques

A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use

Nonhuman primate models for HIV cure research

Mucosal Topical Microbicide Candidates Exert Influence on the Subsequent SIV Infection and Survival by Regulating SIV-Specific T-Cell Immune Responses

SIV Coreceptor Specificity in Natural and Non-Natural Host Infection: Implications for Cell Targeting and Differential Outcomes from Infection

A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants

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