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Polygenic risk scores: from research tools to clinical instruments

Genome medicine, 2020-05, Vol.12 (1), p.44-44, Article 44

2020

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PRSice: Polygenic Risk Score software

Bioinformatics, 2015-05, Vol.31 (9), p.1466-1468

2015

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Prospects for using risk scores in polygenic medicine

Genome medicine, 2017-11, Vol.9 (1), p.96-96, Article 96

2017

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Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK

Scientific reports, 2022-01, Vol.12 (1), p.459-459, Article 459

2022

Volltextzugriff (PDF)

Uncovering the Genetic Architecture of Major Depression

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (1), p.91-103

2019

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Evaluation of polygenic prediction methodology within a reference-standardized framework

PLoS genetics, 2021-05, Vol.17 (5), p.e1009021-e1009021

2021

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A bidirectional relationship between depression and the autoimmune disorders - New perspectives from the National Child Development Study

PloS one, 2017-03, Vol.12 (3), p.e0173015-e0173015

2017

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Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures

BMC medicine, 2021-10, Vol.19 (1), p.240-18, Article 240

2021

Volltextzugriff (PDF)

Contribution of Common Genetic Variants to Antidepressant Response

Biological psychiatry (1969), 2013-04, Vol.73 (7), p.679-682

2013

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Examining the association between family status and depression in the UK Biobank

Journal of affective disorders, 2021-01, Vol.279, p.585-598

2021

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Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Molecular psychiatry, 2021-07, Vol.26 (7), p.3363-3373

2021

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Combining clinical variables to optimize prediction of antidepressant treatment outcomes

Journal of psychiatric research, 2016-07, Vol.78, p.94-102

2016

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Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Genome Biology, 2018-11, Vol.19 (1), p.194-194, Article 194

2018

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Comorbid medical illness in bipolar disorder

British journal of psychiatry, 2014-12, Vol.205 (6), p.465-472

2014

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Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores

Frontiers in genetics, 2020-06, Vol.11, p.578

2020

Volltextzugriff (PDF)

ukbtools: An R package to manage and query UK Biobank data

PloS one, 2019-05, Vol.14 (5), p.e0214311-e0214311

2019

Volltextzugriff (PDF)

Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: A candidate gene approach

PloS one, 2023-11, Vol.18 (11), p.e0294045-e0294045

2023

Volltextzugriff (PDF)

Genetic association studies: design, analysis and interpretation

Briefings in bioinformatics, 2002-06, Vol.3 (2), p.146-153

LEWIS, Cathryn M

2002

Volltextzugriff (PDF)

Common Genetic Variation and Antidepressant Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Genome-Wide Pharmacogenetic Studies

The American journal of psychiatry, 2013-02, Vol.170 (2), p.207-217

2013

Volltextzugriff (PDF)

Studying individual risk factors for self-harm in the UK Biobank: A polygenic scoring and Mendelian randomisation study

PLoS medicine, 2020-06, Vol.17 (6), p.e1003137

2020

Volltextzugriff (PDF)

Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis

Schizophrenia bulletin, 2016-09, Vol.42 (5), p.1262-1269

2016

Volltextzugriff (PDF)

From SNPs to genes: disease association at the gene level

PloS one, 2011-06, Vol.6 (6), p.e20133-e20133

2011

Volltextzugriff (PDF)

The impact of major depressive disorder on glycaemic control in type 2 diabetes: a longitudinal cohort study using UK Biobank primary care records

BMC medicine, 2024-05, Vol.22 (1), p.211-211, Article 211

2024

Volltextzugriff (PDF)

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

The American journal of psychiatry, 2010-05, Vol.167 (5), p.555-564

2010

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Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

PloS one, 2018-09, Vol.13 (9), p.e0203896

2018

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Polygenic risk scores: from research tools to clinical instruments

PRSice: Polygenic Risk Score software

Prospects for using risk scores in polygenic medicine

Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK

Uncovering the Genetic Architecture of Major Depression

Evaluation of polygenic prediction methodology within a reference-standardized framework

A bidirectional relationship between depression and the autoimmune disorders - New perspectives from the National Child Development Study

Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures

Contribution of Common Genetic Variants to Antidepressant Response

Examining the association between family status and depression in the UK Biobank

Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Combining clinical variables to optimize prediction of antidepressant treatment outcomes

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

Comorbid medical illness in bipolar disorder

Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores

ukbtools: An R package to manage and query UK Biobank data

Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: A candidate gene approach

Genetic association studies: design, analysis and interpretation

Common Genetic Variation and Antidepressant Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Genome-Wide Pharmacogenetic Studies

Studying individual risk factors for self-harm in the UK Biobank: A polygenic scoring and Mendelian randomisation study

Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis

From SNPs to genes: disease association at the gene level

The impact of major depressive disorder on glycaemic control in type 2 diabetes: a longitudinal cohort study using UK Biobank primary care records

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts

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