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Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K

Pharmaceutical research, 2018-08, Vol.35 (8), p.159-8, Article 159

2018

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Similarity-based SIBAR descriptors for classification of chemically diverse hERG blockers

Molecular diversity, 2009-08, Vol.13 (3), p.321-336

2009

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Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities

Journal of pharmacokinetics and pharmacodynamics, 2015-12, Vol.42 (6), p.659-679

2015

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Chemical Inhibitors of the Calcium Entry Channel TRPV6

Pharmaceutical research, 2011-02, Vol.28 (2), p.322-330

2011

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Synthesis, characterization, and pharmacological evaluation of benzothiopyran derivatives as a novel class of calcium channel blockers

Medicinal chemistry research, 2013-05, Vol.22 (5), p.2188-2195

2013

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Voltage-gated sodium channel blockers, 2001-2006: An overview

Medicinal chemistry research, 2008-06, Vol.17 (2-7), p.356-368

2008

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Machine learning models for classification tasks related to drug safety

Molecular diversity, 2021-08, Vol.25 (3), p.1409-1424

2021

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Binary Blend of Glyceryl Monooleate and Glyceryl Monostearate for Magnetically Induced Thermo-Responsive Local Drug Delivery System

Pharmaceutical research, 2013-12, Vol.30 (12), p.3214-3224

2013

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Functional relaxant effect of 6,7-dipropoxy-2H-chromen-2-one is mainly by calcium channel blockade in ex vivo assay of tracheal rings

Medicinal chemistry research, 2019-08, Vol.28 (8), p.1197-1204

2019

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Synthesis of a New Series of 4-Aryl-1,4-Dihydropyridines with Calcium Channel Blocking and Vasodilatory Activity

Medicinal chemistry research, 2012-06, Vol.21 (6), p.908-921

2012

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Substituted 9-aryl-1,8-acridinedione derivatives and their effects on potassium channels

Medicinal chemistry research, 2009, Vol.18 (4), p.317-325

2009

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A quantitative systems pharmacology model of plasma potassium regulation by the kidney and aldosterone

Journal of pharmacokinetics and pharmacodynamics, 2022-08, Vol.49 (4), p.471-486

2022

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Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings

Medicinal chemistry research, 2014, Vol.23 (1), p.526-552

2014

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Drug–physiology interaction and its influence on the QT prolongation-mechanistic modeling study

Journal of pharmacokinetics and pharmacodynamics, 2018-06, Vol.45 (3), p.483-490

2018

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Integrated TK–TD modeling for drug-induced concurrent tachycardia and QT changes in beagle dogs

Journal of pharmacokinetics and pharmacodynamics, 2017-10, Vol.44 (5), p.449-462

2017

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Skin Absorption of Anions: Part One. Methodology for In Vitro Cutaneous Absorption Measurements

Pharmaceutical research, 2016-07, Vol.33 (7), p.1564-1575

2016

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chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis

Molecular diversity, 2009-02, Vol.13 (1), p.5-25

2009

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Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes

Molecular diversity, 2017-08, Vol.21 (3), p.533-546

2017

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Design, synthesis, and antihypertensive activity of new pyrimidine derivatives endowing new pharmacophores

Medicinal chemistry research, 2019-03, Vol.28 (3), p.360-379

2019

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Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors

Molecular diversity, 2023-08, Vol.27 (4), p.1735-1749

2023

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Recent strategies in the synthesis of thiophene derivatives: highlights from the 2012–2020 literature

Molecular diversity, 2021-11, Vol.25 (4), p.2571-2604

2021

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Synthesis and antiseizure activity of (E)-1,2-diarylethylidenehydrazine carboximidamides against tonic-clonic seizures: an intracerebroventricular and electrophysiological study

Medicinal chemistry research, 2020-08, Vol.29 (8), p.1520-1535

2020

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Synthesis, characterization, and biological activities of 4-imino-3-arylazo-4H-pyrimido[2,1-b][1,3]benzothiazole-2-oles

Medicinal chemistry research, 2014-08, Vol.23 (8), p.3733-3743

2014

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Novel approach for synthesis of potent antimicrobial hybrid molecules containing pyrimidine-based imidazole scaffolds

Medicinal chemistry research, 2014-10, Vol.23 (10), p.4395-4403

2014

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3,4-Dihydropyrimidin-2(1H)-one derivatives: Organocatalysed microwave assisted synthesis and evaluation of their antioxidant activity

Medicinal chemistry research, 2012-12, Vol.21 (12), p.4506-4511

2012

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Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K

Similarity-based SIBAR descriptors for classification of chemically diverse hERG blockers

Modelling of drug-induced QT-interval prolongation: estimation approaches and translational opportunities

Chemical Inhibitors of the Calcium Entry Channel TRPV6

Synthesis, characterization, and pharmacological evaluation of benzothiopyran derivatives as a novel class of calcium channel blockers

Voltage-gated sodium channel blockers, 2001-2006: An overview

Machine learning models for classification tasks related to drug safety

Binary Blend of Glyceryl Monooleate and Glyceryl Monostearate for Magnetically Induced Thermo-Responsive Local Drug Delivery System

Functional relaxant effect of 6,7-dipropoxy-2H-chromen-2-one is mainly by calcium channel blockade in ex vivo assay of tracheal rings

Synthesis of a New Series of 4-Aryl-1,4-Dihydropyridines with Calcium Channel Blocking and Vasodilatory Activity

Substituted 9-aryl-1,8-acridinedione derivatives and their effects on potassium channels

A quantitative systems pharmacology model of plasma potassium regulation by the kidney and aldosterone

Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings

Drug–physiology interaction and its influence on the QT prolongation-mechanistic modeling study

Integrated TK–TD modeling for drug-induced concurrent tachycardia and QT changes in beagle dogs

Skin Absorption of Anions: Part One. Methodology for In Vitro Cutaneous Absorption Measurements

chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis

Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes

Design, synthesis, and antihypertensive activity of new pyrimidine derivatives endowing new pharmacophores

Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors

Recent strategies in the synthesis of thiophene derivatives: highlights from the 2012–2020 literature

Synthesis and antiseizure activity of (E)-1,2-diarylethylidenehydrazine carboximidamides against tonic-clonic seizures: an intracerebroventricular and electrophysiological study

Synthesis, characterization, and biological activities of 4-imino-3-arylazo-4H-pyrimido[2,1-b][1,3]benzothiazole-2-oles

Novel approach for synthesis of potent antimicrobial hybrid molecules containing pyrimidine-based imidazole scaffolds

3,4-Dihydropyrimidin-2(1H)-one derivatives: Organocatalysed microwave assisted synthesis and evaluation of their antioxidant activity

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