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IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

Cancers, 2020-11, Vol.12 (11), p.3464

2020

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Detection of KRAS Mutations in Circulating Tumor DNA by Digital PCR in Early Stages of Pancreatic Cancer

Clinical chemistry (Baltimore, Md.), 2016-11, Vol.62 (11), p.1482-1491

2016

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EGFR overexpression is not common in patients with head and neck cancer. Cell lines are not representative for the clinical situation in this indication

Oncotarget, 2018-06, Vol.9 (48), p.28965-28975

2018

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Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis

Molecular oncology, 2024-03, Vol.18 (3), p.726-742

2024

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High-Throughput Screening for Kinase Inhibitors

Chembiochem : a European journal of chemical biology, 2005-03, Vol.6 (3), p.481-490

2005

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Circulating endothelial cells as biomarker for cardiovascular diseases

Research and practice in thrombosis and haemostasis, 2019-01, Vol.3 (1), p.49-58

2019

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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses

Clinical and experimental medicine, 2023-12, Vol.23 (8), p.5445-5461

2023

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Hepatocyte Growth Factor Receptor overexpression predicts reduced survival but its targeting is not effective in unselected HNSCC patients

Head & neck, 2020-04, Vol.42 (4), p.625-635

2020

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ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

Oncotarget, 2016-10, Vol.7 (43), p.70323-70335

2016

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Cytochrome c Maintains Mitochondrial Transmembrane Potential and ATP Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

The Journal of cell biology, 2001-04, Vol.153 (2), p.319-328

2001

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Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

The Journal of cell biology, 2000-09, Vol.150 (5), p.1027-1036

2000

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Global Transcriptome Analysis of Genetically Identified Neurons in the Adult Cortex

The Journal of neuroscience, 2006-09, Vol.26 (39), p.9956-9966

2006

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Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

ChemMedChem, 2015-12, Vol.10 (12), p.2004-2013

2015

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Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases

Experimental dermatology, 2011-01, Vol.20 (1), p.41-47

2011

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Assay concordance between SPA and TR-FRET in high-throughput screening

Journal of biomolecular screening, 2006-09, Vol.11 (6), p.606-616

2006

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A miniaturized high-throughput screening assay for fucosyltransferase VII

Analytical biochemistry, 2008, Vol.372 (1), p.96-105

2008

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Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells

Clinical cancer research, 2016-05, Vol.22 (9), p.2197-2206

2016

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Abstract 3792: Improved isolation and detection of circulating tumor cells of pancreatic cancer patients with characterization by mutational analysis

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3792-3792

2017

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Abstract 413: Validation of an antibody independent tool for patient selection: RNA in situ hybridization detects Met expression levels predictive for response to Met inhibition by Bay 853474

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.413-413

2016

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Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4

Journal of neurochemistry, 2004-03, Vol.88 (5), p.1114-1126

2004

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Abstract 2786: EGFR expression and phosphorylation in HNSCC predict response to EGFR inhibition but cell lines are not representative for the clinical situation

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2786-2786

2017

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Abstract 2389: Role of MET in head and neck cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2389-2389

2018

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Heterogeneous PSMA expression on circulating tumor cells: a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer

Oncotarget, 2016-06, Vol.7 (23), p.34930-34941

2016

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Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4825-4825

2019

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IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

Detection of KRAS Mutations in Circulating Tumor DNA by Digital PCR in Early Stages of Pancreatic Cancer

EGFR overexpression is not common in patients with head and neck cancer. Cell lines are not representative for the clinical situation in this indication

Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis

High-Throughput Screening for Kinase Inhibitors

Circulating endothelial cells as biomarker for cardiovascular diseases

Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses

Hepatocyte Growth Factor Receptor overexpression predicts reduced survival but its targeting is not effective in unselected HNSCC patients

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction

Cytochrome c Maintains Mitochondrial Transmembrane Potential and ATP Generation after Outer Mitochondrial Membrane Permeabilization during the Apoptotic Process

Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

Global Transcriptome Analysis of Genetically Identified Neurons in the Adult Cortex

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

Inhibition of the IL-2-inducible tyrosine kinase (Itk) activity: a new concept for the therapy of inflammatory skin diseases

Assay concordance between SPA and TR-FRET in high-throughput screening

A miniaturized high-throughput screening assay for fucosyltransferase VII

Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells

Abstract 3792: Improved isolation and detection of circulating tumor cells of pancreatic cancer patients with characterization by mutational analysis

Abstract 413: Validation of an antibody independent tool for patient selection: RNA in situ hybridization detects Met expression levels predictive for response to Met inhibition by Bay 853474

Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4

Abstract 2786: EGFR expression and phosphorylation in HNSCC predict response to EGFR inhibition but cell lines are not representative for the clinical situation

Abstract 2389: Role of MET in head and neck cancer

Heterogeneous PSMA expression on circulating tumor cells: a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer

Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

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