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Linking ADHD to the Neural Circuitry of Attention

Trends in cognitive sciences, 2017-06, Vol.21 (6), p.474-488

2017

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A decision support framework for genomically informed investigational cancer therapy

JNCI : Journal of the National Cancer Institute, 2015-07, Vol.107 (7), p.1

2015

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Targeting BRAF -Mutant Colorectal Cancer: Progress in Combination Strategies

Cancer discovery, 2017-06, Vol.7 (6), p.558-560

2017

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Targeting TRK family proteins in cancer

Pharmacology & therapeutics (Oxford), 2017-05, Vol.173, p.58-66

2017

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Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer

Current pharmaceutical biotechnology, 2014-01, Vol.15 (5), p.475-485

2014

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Interleukin-6 and its receptor in cancer : Implications for translational therapeutics

Cancer, 2007-11, Vol.110 (9), p.1911-1928

2007

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Inhibition of Src Expression and Activity Inhibits Tumor Progression and Metastasis of Human Pancreatic Adenocarcinoma Cells in an Orthotopic Nude Mouse Model

The American journal of pathology, 2006-03, Vol.168 (3), p.962-972

2006

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A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas

Journal of clinical oncology, 2023-03, Vol.41 (9), p.1714-1724

2023

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Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials

British journal of cancer, 2020-11, Vol.123 (10), p.1496-1501

2020

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Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53

Clinical cancer research, 2021-10, Vol.27 (19), p.5236-5247

2021

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Activation of 4-1BB on Liver Myeloid Cells Triggers Hepatitis via an Interleukin-27-Dependent Pathway

Clinical cancer research, 2018-03, Vol.24 (5), p.1138-1151

2018

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Diet-related interventions for cancer-associated cachexia

Journal of cancer research and clinical oncology, 2021-05, Vol.147 (5), p.1443-1450

2021

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First‐in‐human, phase I study of PF‐06647263, an anti‐EFNA4 calicheamicin antibody–drug conjugate, in patients with advanced solid tumors

International journal of cancer, 2019-10, Vol.145 (7), p.1798-1808

2019

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Preclinical Evaluation and Phase Ib Study of Prexasertib, a CHK1 Inhibitor, and Samotolisib (LY3023414), a Dual PI3K/mTOR Inhibitor

Clinical cancer research, 2021-04, Vol.27 (7), p.1864-1874

2021

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Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors

Cancer treatment reviews, 2014-09, Vol.40 (8), p.990-1004

2014

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Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease

Neuro-oncology (Charlottesville, Va.), 2023-08, Vol.25 (8), p.1415-1427

2023

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Strategies for combining immunotherapy with radiation for anticancer therapy

Immunotherapy, 2015-09, Vol.7 (9), p.967-980

2015

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Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation

Cancer discovery, 2016-12, Vol.6 (12), p.1352

2016

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Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core

Nature structural & molecular biology, 2020-05, Vol.27 (5), p.417-423

2020

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PathBank: a comprehensive pathway database for model organisms

Nucleic acids research, 2020-01, Vol.48 (D1), p.D470-D478

2020

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Three-dimensional organization of nascent rod outer segment disk membranes

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (48), p.14870-14875

2015

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Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

The Journal of clinical investigation, 2013-03, Vol.123 (3), p.1241-1261

2013

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CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells

Carcinogenesis (New York), 2018-02, Vol.39 (2), p.242-251

2018

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Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (27), p.9977-9982

2014

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CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (14), p.3870-3884

2017

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Linking ADHD to the Neural Circuitry of Attention

A decision support framework for genomically informed investigational cancer therapy

Targeting BRAF -Mutant Colorectal Cancer: Progress in Combination Strategies

Targeting TRK family proteins in cancer

Impact of microRNAs in resistance to chemotherapy and novel targeted agents in non-small cell lung cancer

Interleukin-6 and its receptor in cancer : Implications for translational therapeutics

Inhibition of Src Expression and Activity Inhibits Tumor Progression and Metastasis of Human Pancreatic Adenocarcinoma Cells in an Orthotopic Nude Mouse Model

A First-in-Human Phase I Study of Milademetan, an MDM2 Inhibitor, in Patients With Advanced Liposarcoma, Solid Tumors, or Lymphomas

Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials

Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53

Activation of 4-1BB on Liver Myeloid Cells Triggers Hepatitis via an Interleukin-27-Dependent Pathway

Diet-related interventions for cancer-associated cachexia

First‐in‐human, phase I study of PF‐06647263, an anti‐EFNA4 calicheamicin antibody–drug conjugate, in patients with advanced solid tumors

Preclinical Evaluation and Phase Ib Study of Prexasertib, a CHK1 Inhibitor, and Samotolisib (LY3023414), a Dual PI3K/mTOR Inhibitor

Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors

Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease

Strategies for combining immunotherapy with radiation for anticancer therapy

Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation

Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core

PathBank: a comprehensive pathway database for model organisms

Three-dimensional organization of nascent rod outer segment disk membranes

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib

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