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Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis

Advanced drug delivery reviews, 2009-07, Vol.61 (7), p.554-571

2009

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DNp73 Exerts Function in Metastasis Initiation by Disconnecting the Inhibitory Role of EPLIN on IGF1R-AKT/STAT3 Signaling

Cancer cell, 2013-10, Vol.24 (4), p.512-527

2013

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Artificial riboswitches for gene expression and replication control of DNA and RNA viruses

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (5), p.1674-1674

2014

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Targeting of autoantigens to DEC205⁺ dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice

The Journal of immunology (1950), 2013-09, Vol.191 (6), p.2938-2947

2013

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Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeutics

mAbs, 2021-01, Vol.13 (1), p.1982447-1982447

2021

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Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses

Nucleic acids research, 2012-11, Vol.40 (21), p.e167

2012

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Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy

Molecular therapy. Oncolytics, 2017-03, Vol.4 (C), p.77-86

2017

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Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16018-16018, Article 16018

2016

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German Cancer Consortium (DKTK) – A national consortium for translational cancer research

Molecular oncology, 2019-03, Vol.13 (3), p.535-542

2019

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Virotherapy Research in Germany: From Engineering to Translation

Human gene therapy, 2017-10, Vol.28 (10), p.800

2017

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Mild hyperthermia enhances human monocyte-derived dendritic cell functions and offers potential for applications in vaccination strategies

International journal of hyperthermia, 2011-09, Vol.27 (6), p.591-603

2011

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Retargeting of Rat Parvovirus H-1PV to Cancer Cells through Genetic Engineering of the Viral Capsid

Journal of Virology, 2012-04, Vol.86 (7), p.3452-3465

2012

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CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy

Molecular therapy, 2014-11, Vol.22 (11), p.1949-1959

2014

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Multiple Interferon Regulatory Factor and NF-κB Sites Cooperate in Mediating Cell-Type- and Maturation-Specific Activation of the Human CD83 Promoter in Dendritic Cells

Molecular and Cellular Biology, 2013-04, Vol.33 (7), p.1331-1344

2013

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Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds

PloS one, 2014-04, Vol.9 (4), p.e95723-e95723

2014

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Inhibition of Melanoma Growth by Targeting of Antigen to Dendritic Cells via an Anti-DEC-205 Single-Chain Fragment Variable Molecule

Clinical cancer research, 2008-12, Vol.14 (24), p.8169-8177

2008

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Engineered adenoviruses combine enhanced oncolysis with improved virus production by mesenchymal stromal carrier cells

International journal of cancer, 2015-08, Vol.137 (4), p.978-990

2015

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Generation of an Adenovirus-Parvovirus Chimera with Enhanced Oncolytic Potential

Journal of Virology, 2012-10, Vol.86 (19), p.10418-10431

2012

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Virus chimeras for gene therapy, vaccination, and oncolysis: adenoviruses and beyond

Trends in molecular medicine, 2012-07, Vol.18 (7), p.365-376

2012

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Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

Journal of Immunology Research, 2016-01, Vol.2016, p.6078473-17

2016

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Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis

PloS one, 2011-11, Vol.6 (11), p.e27934-e27934

2011

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Cellular genetic tools to control oncolytic adenoviruses for virotherapy of cancer

Journal of molecular medicine (Berlin, Germany), 2008-04, Vol.86 (4), p.363-377

Nettelbeck, Dirk M.

2008

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Tropism Modification of Adenovirus Vectors by Peptide Ligand Insertion into Various Positions of the Adenovirus Serotype 41 Short-Fiber Knob Domain

Journal of Virology, 2007-03, Vol.81 (6), p.2688-2699

2007

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Triple-Targeted Oncolytic Adenoviruses Featuring the Cox2 Promoter, E1A Transcomplementation, and Serotype Chimerism for Enhanced Selectivity for Ovarian Cancer Cells

Molecular therapy, 2006-08, Vol.14 (2), p.164-174

2006

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Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis

DNp73 Exerts Function in Metastasis Initiation by Disconnecting the Inhibitory Role of EPLIN on IGF1R-AKT/STAT3 Signaling

Artificial riboswitches for gene expression and replication control of DNA and RNA viruses

Targeting of autoantigens to DEC205⁺ dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice

Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeutics

Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses

Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

Virotherapy in Germany-Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

German Cancer Consortium (DKTK) – A national consortium for translational cancer research

Virotherapy Research in Germany: From Engineering to Translation

Mild hyperthermia enhances human monocyte-derived dendritic cell functions and offers potential for applications in vaccination strategies

Retargeting of Rat Parvovirus H-1PV to Cancer Cells through Genetic Engineering of the Viral Capsid

CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy

Multiple Interferon Regulatory Factor and NF-κB Sites Cooperate in Mediating Cell-Type- and Maturation-Specific Activation of the Human CD83 Promoter in Dendritic Cells

Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds

Inhibition of Melanoma Growth by Targeting of Antigen to Dendritic Cells via an Anti-DEC-205 Single-Chain Fragment Variable Molecule

Engineered adenoviruses combine enhanced oncolysis with improved virus production by mesenchymal stromal carrier cells

Generation of an Adenovirus-Parvovirus Chimera with Enhanced Oncolytic Potential

Virus chimeras for gene therapy, vaccination, and oncolysis: adenoviruses and beyond

Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis

Cellular genetic tools to control oncolytic adenoviruses for virotherapy of cancer

Tropism Modification of Adenovirus Vectors by Peptide Ligand Insertion into Various Positions of the Adenovirus Serotype 41 Short-Fiber Knob Domain

Triple-Targeted Oncolytic Adenoviruses Featuring the Cox2 Promoter, E1A Transcomplementation, and Serotype Chimerism for Enhanced Selectivity for Ovarian Cancer Cells

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