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Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

Journal of medicinal chemistry, 2005-08, Vol.48 (17), p.5504-5508

2005

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Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

Antimicrobial Agents and Chemotherapy, 2004-02, Vol.48 (2), p.651-654

2004

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Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1712-1715

2006

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Development and evaluation of an automated hepatitis C virus NS5B sequence-based subtyping assay

Clinical chemistry and laboratory medicine, 2010-08, Vol.48 (8), p.1095-1102

2010

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Second-generation line probe assay for hepatitis C virus genotyping

Journal of Clinical Microbiology, 1996-09, Vol.34 (9), p.2259-2266

1996

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Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization

Archives of virology, 1998-01, Vol.143 (12), p.2493-2503

1998

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Inhibition of Hepatitis C Replicon RNA Synthesis by β-D-2′-deoxy-2′-fluoro-2′-C-Methylcytidine: A Specific Inhibitor of Hepatitis C Virus Replication

Antiviral chemistry & chemotherapy, 2006, Vol.17 (2), p.79-87

2006

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Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

Journal of general virology, 1993-06, Vol.74 (6), p.1093-1102

1993

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Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C

The Journal of infectious diseases, 1995-06, Vol.171 (6), p.1607

1995

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Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b

Methods in molecular biology (Clifton, N.J.), 2013, Vol.1030, p.137

2013

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Full genome sequence of three isolates of hepatitis C virus subtype 4b from Portugal

Archives of virology, 2009-01, Vol.154 (1), p.127-132

2009

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Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users

Journal of medical virology, 2006-10, Vol.78 (10), p.1296-1303

2006

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Classification of Hepatitis C Viruses Based on Phylogenetic Analysis of the Envelope 1 and Nonstructural 5B Regions and Identification of Five Additional Subtypes

Proceedings of the National Academy of Sciences - PNAS, 1994-10, Vol.91 (21), p.10134-10138

1994

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Evidence for high genetic diversity and long-term endemicity of hepatitis C virus genotypes 1 and 2 in West Africa

Journal of medical virology, 1998-06, Vol.55 (2), p.92-97

1998

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Synthesis and Biological Activity of 5′,9-Anhydro-3-Purine-ISONucleosides as Potential Anti-Hepatitis C Virus Agents

Nucleosides, nucleotides & nucleic acids, 2007-01, Vol.26 (1), p.83-97

2007

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Synthesis of 5'-C-methyl-1', 3'-dioxolan-4'-yl nucleosides

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1243-1245

2004

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HCV infection in a rural population of the Central African republic (CAR): Evidence for three additional subtypes of genotype 4

Journal of medical virology, 1995-12, Vol.47 (4), p.435-437

1995

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Metabolism of the Anti-Hepatitis C Virus Nucleoside beta -D-N super(4)- Hydroxycytidine in Different Liver Cells

Antimicrobial agents and chemotherapy, 2004-12, Vol.48 (12), p.4636-4642

2004

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Mechanism of Activation of {szligbeta}-D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Antimicrobial agents and chemotherapy, 2007-02, Vol.51 (2), p.503-509

2007

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Synthesis and Structure-Activity Relationships of Novel Anti-hepatitis C Agents: N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl)- vic-triazolo[4,5-b]pyridin-5-one Derivatives

Journal of medicinal chemistry, 2005-10, Vol.48 (20), p.6454-6460

2005

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Synthesis of N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl) -vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity

Journal of medicinal chemistry, 2004-11, Vol.47 (24), p.6100-6103

2004

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Synthesis of β-Enantiomers of N4-Hydroxy-3′-Deoxy-Pyrimidine Nucleosides and Their Evaluation against Bovine Viral Diarrhoea Virus and Hepatitis C Virus in Cell Culture

Antiviral chemistry & chemotherapy, 2004-02, Vol.15 (1), p.43-55

2004

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Analysis of the Putative E1 Envelope and NS4a Epitope Regions of HCV Type 3

Biochemical and biophysical research communications, 1993-04, Vol.192 (2), p.635-641

1993

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Sequence analysis of hepatitis C virus genotypes 1 to 5 reveals multiple novel subtypes in the Benelux countries

Journal of general virology, 1995-07, Vol.76 (7), p.1871-1876

1995

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Significance of anti-hepatitis C virus core IgM antibodies in patients with chronic hepatitis C

Journal of medical virology, 1995-11, Vol.47 (3), p.285-291

1995

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Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Development and evaluation of an automated hepatitis C virus NS5B sequence-based subtyping assay

Second-generation line probe assay for hepatitis C virus genotyping

Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization

Inhibition of Hepatitis C Replicon RNA Synthesis by β-D-2′-deoxy-2′-fluoro-2′-C-Methylcytidine: A Specific Inhibitor of Hepatitis C Virus Replication

Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C

Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b

Full genome sequence of three isolates of hepatitis C virus subtype 4b from Portugal

Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users

Classification of Hepatitis C Viruses Based on Phylogenetic Analysis of the Envelope 1 and Nonstructural 5B Regions and Identification of Five Additional Subtypes

Evidence for high genetic diversity and long-term endemicity of hepatitis C virus genotypes 1 and 2 in West Africa

Synthesis and Biological Activity of 5′,9-Anhydro-3-Purine-ISONucleosides as Potential Anti-Hepatitis C Virus Agents

Synthesis of 5'-C-methyl-1', 3'-dioxolan-4'-yl nucleosides

HCV infection in a rural population of the Central African republic (CAR): Evidence for three additional subtypes of genotype 4

Metabolism of the Anti-Hepatitis C Virus Nucleoside beta -D-N super(4)- Hydroxycytidine in Different Liver Cells

Mechanism of Activation of {szligbeta}-D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Synthesis and Structure-Activity Relationships of Novel Anti-hepatitis C Agents: N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl)- vic-triazolo[4,5-b]pyridin-5-one Derivatives

Synthesis of N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl) -vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity

Synthesis of β-Enantiomers of N4-Hydroxy-3′-Deoxy-Pyrimidine Nucleosides and Their Evaluation against Bovine Viral Diarrhoea Virus and Hepatitis C Virus in Cell Culture

Analysis of the Putative E1 Envelope and NS4a Epitope Regions of HCV Type 3

Sequence analysis of hepatitis C virus genotypes 1 to 5 reveals multiple novel subtypes in the Benelux countries

Significance of anti-hepatitis C virus core IgM antibodies in patients with chronic hepatitis C

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