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Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9

Cell stem cell, 2015-08, Vol.17 (2), p.213-220

2015

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Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons

Cell reports (Cambridge), 2015-10, Vol.13 (2), p.234-241

2015

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Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9253-9258

2014

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Universal Correction of Blood Coagulation Factor VIII in Patient-Derived Induced Pluripotent Stem Cells Using CRISPR/Cas9

Stem cell reports, 2019-06, Vol.12 (6), p.1242-1249

2019

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EW‐7203, a novel small molecule inhibitor of transforming growth factor‐β (TGF‐β) type I receptor/activin receptor‐like kinase‐5, blocks TGF‐β1‐mediated epithelial‐to‐mesenchymal transition in mammary epithelial cells

Cancer science, 2011-10, Vol.102 (10), p.1889-1896

2011

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EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung

European journal of cancer (1990), 2011-11, Vol.47 (17), p.2642-2653

2011

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Therapeutic correction of hemophilia A using 2D endothelial cells and multicellular 3D organoids derived from CRISPR/Cas9-engineered patient iPSCs

Biomaterials, 2022-04, Vol.283, p.121429-121429, Article 121429

2022

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Genome Editing of Structural Variations: Modeling and Gene Correction

Trends in biotechnology (Regular ed.), 2016-07, Vol.34 (7), p.548-561

2016

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Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson's disease

Cell stem cell, 2024-01, Vol.31 (1), p.25-38.e8

2024

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ABCD2 is a direct target of β-catenin and TCF-4: implications for X-linked adrenoleukodystrophy therapy

PloS one, 2013-02, Vol.8 (2), p.e56242

2013

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Genome-editing technologies for gene correction of hemophilia

Human Genetics, 2016-09, Vol.135 (9), p.977-981

2016

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PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

Stem cell reports, 2015-05, Vol.4 (5), p.821-834

2015

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An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial–mesenchymal transition

Cancer letters, 2014-08, Vol.351 (1), p.72-80

2014

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Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

The Journal of biological chemistry, 2009-04, Vol.284 (14), p.9237-9246

2009

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Nonstructural 5A protein activates β-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis

Journal of hepatology, 2009-11, Vol.51 (5), p.853-864

2009

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Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5- a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (20), p.6049-6053

2011

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Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Bioorganic & medicinal chemistry, 2011-04, Vol.19 (8), p.2633-2640

2011

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Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3917-3925

2011

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Comparison of the rabbit pyrogen test and Limulus amoebocyte lysate (LAL) assay for endotoxin in hepatitis B vaccines and the effect of aluminum hydroxide

Biologicals, 2005-09, Vol.33 (3), p.145-151

2005

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Comparison of the stability of postoperative alignment in sensory exotropia: adjustable versus non-adjustable surgery

Korean Journal of Ophthalmology, 2009, 23(4), , pp.277-280

2009

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Virulence attenuation of Streptococcus pneumoniae clpP mutant by sensitivity to oxidative stress in macrophages via an NO-mediated pathway

The Journal of Microbiology, 2010, 48(2), , pp.229-235

2010

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Biodegradable intrascleral implant of triamcinolone acetonide in experimental uveitis

Journal of ocular pharmacology and therapeutics, 2009-06, Vol.25 (3), p.201-208

2009

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Analysis and Modification of Thiols in the Hemolymph Juvenile Hormone Binding Protein of Manduca sexta

Archives of biochemistry and biophysics, 1993-04, Vol.302 (1), p.12-18

1993

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Affinity purification and binding analysis of the hemolymph juvenile hormone binding protein from Manduca sexta

Biochemistry (Easton), 1993-08, Vol.32 (31), p.7909-7915

1993

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cDNA cloning and induction of tyrosine hydroxylase gene from the diamondback moth, Plutella xylostella

Archives of insect biochemistry and physiology, 2010-10, Vol.75 (2), p.107-120

2010

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Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9

Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

Universal Correction of Blood Coagulation Factor VIII in Patient-Derived Induced Pluripotent Stem Cells Using CRISPR/Cas9

EW‐7203, a novel small molecule inhibitor of transforming growth factor‐β (TGF‐β) type I receptor/activin receptor‐like kinase‐5, blocks TGF‐β1‐mediated epithelial‐to‐mesenchymal transition in mammary epithelial cells

EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung

Therapeutic correction of hemophilia A using 2D endothelial cells and multicellular 3D organoids derived from CRISPR/Cas9-engineered patient iPSCs

Genome Editing of Structural Variations: Modeling and Gene Correction

Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson's disease

ABCD2 is a direct target of β-catenin and TCF-4: implications for X-linked adrenoleukodystrophy therapy

Genome-editing technologies for gene correction of hemophilia

PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial–mesenchymal transition

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

Nonstructural 5A protein activates β-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis

Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5- a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Comparison of the rabbit pyrogen test and Limulus amoebocyte lysate (LAL) assay for endotoxin in hepatitis B vaccines and the effect of aluminum hydroxide

Comparison of the stability of postoperative alignment in sensory exotropia: adjustable versus non-adjustable surgery

Virulence attenuation of Streptococcus pneumoniae clpP mutant by sensitivity to oxidative stress in macrophages via an NO-mediated pathway

Biodegradable intrascleral implant of triamcinolone acetonide in experimental uveitis

Analysis and Modification of Thiols in the Hemolymph Juvenile Hormone Binding Protein of Manduca sexta

Affinity purification and binding analysis of the hemolymph juvenile hormone binding protein from Manduca sexta

cDNA cloning and induction of tyrosine hydroxylase gene from the diamondback moth, Plutella xylostella

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