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Seven transmembrane receptors: something old, something new

Acta Physiologica, 2007-05, Vol.190 (1), p.9-19

Lefkowitz, R.J

2007

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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Science (American Association for the Advancement of Science), 1999-12, Vol.286 (5449), p.2495-2498

1999

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Desensitization of G protein-coupled receptors and neuronal functions

Annual review of neuroscience, 2004-01, Vol.27 (1), p.107-144

2004

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Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Current Opinion in Cell Biology, 2001-04, Vol.13 (2), p.139-145

2001

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Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Molecular pharmacology, 2004-07, Vol.66 (1), p.106-112

2004

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β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Science (American Association for the Advancement of Science), 2000-11, Vol.290 (5496), p.1574-1577

2000

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Functional consequences of altering myocardial adrenergic receptor signaling

Annual review of physiology, 2000-01, Vol.62 (1), p.237-260

2000

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Role of Endocytosis in the Activation of the Extracellular Signal-Regulated Kinase Cascade by Sequestering and Nonsequestering G Protein-Coupled Receptors

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1489-1494

2000

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Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

The Journal of clinical investigation, 2001-04, Vol.107 (8), p.967-974

2001

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Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

Trends in pharmacological sciences (Regular ed.), 1993-08, Vol.14 (8), p.303-307

1993

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Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5215), p.1350-1353

1995

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Circulation (New York, N.Y.), 1998-10, Vol.98 (17), p.1783-1789

1998

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Enhanced myocardial function in transgenic mice overexpressing the β2-adrenergic receptor

Science (American Association for the Advancement of Science), 1994-04, Vol.264 (5158), p.582-586

1994

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G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

American journal of physiology. Lung cellular and molecular physiology, 2004-02, Vol.286 (2), p.312-L319

2004

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Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.10782-10787

2003

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Neuron (Cambridge, Mass.), 1999-12, Vol.24 (4), p.1029-1036

1999

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β-arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes

Science (American Association for the Advancement of Science), 1999-01, Vol.283 (5402), p.655-661

1999

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Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

Progress in neurobiology, 2002-02, Vol.66 (2), p.61-79

2002

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β-Arrestin Inhibits NF-κB Activity by Means of Its Interaction with the NF-κB Inhibitor IκBα

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (23), p.8603-8607

2004

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Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

Circulation research, 2002-10, Vol.91 (8), p.672-680

2002

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Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

The Journal of neuroscience, 2002-12, Vol.22 (23), p.10494-10500

2002

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Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

Molecular pharmacology, 1995-08, Vol.48 (2), p.173-177

1995

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Regulation of tyrosine kinase cascades by G-protein-coupled receptors

Current opinion in cell biology, 1999-04, Vol.11 (2), p.177-183

1999

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1391-1394

2003

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Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1740-1744

2003

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Seven transmembrane receptors: something old, something new

Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Desensitization of G protein-coupled receptors and neuronal functions

Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Functional consequences of altering myocardial adrenergic receptor signaling

Role of Endocytosis in the Activation of the Extracellular Signal-Regulated Kinase Cascade by Sequestering and Nonsequestering G Protein-Coupled Receptors

Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Enhanced myocardial function in transgenic mice overexpressing the β2-adrenergic receptor

G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

β-arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

β-Arrestin Inhibits NF-κB Activity by Means of Its Interaction with the NF-κB Inhibitor IκBα

Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins

Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

Regulation of tyrosine kinase cascades by G-protein-coupled receptors

Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

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