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β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Science (American Association for the Advancement of Science), 2000-11, Vol.290 (5496), p.1574-1577

2000

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Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.10782-10787

2003

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Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart

Circulation research, 2000-01, Vol.86 (1), p.43-43

2000

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Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

Molecular pharmacology, 1995-08, Vol.48 (2), p.173-177

1995

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1391-1394

2003

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Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1740-1744

2003

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Activation and Targeting of Extracellular Signal-Regulated Kinases by β-Arrestin Scaffolds

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (5), p.2449-2454

2001

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β-Arrestin 1 and 2 Differentially Regulate Heptahelical Receptor Signaling and Trafficking

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (4), p.1601-1606

2001

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Cloning and Expression of a Human Kidney cDNA for an α 2-adrenergic Receptor Subtype

Proceedings of the National Academy of Sciences - PNAS, 1988-09, Vol.85 (17), p.6301-6305

1988

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The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9161-9164

1993

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Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function

Proceedings of the National Academy of Sciences - PNAS, 1990-04, Vol.87 (8), p.2896-2900

1990

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G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

Proceedings of the National Academy of Sciences - PNAS, 1995-09, Vol.92 (20), p.9284-9287

1995

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Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning

Molecular pharmacology, 1992-07, Vol.42 (1), p.1-5

1992

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Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2

Proceedings of the National Academy of Sciences - PNAS, 1990-07, Vol.87 (13), p.5094-5098

1990

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Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors

Science (American Association for the Advancement of Science), 1993-03, Vol.259 (5100), p.1453-1457

1993

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Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism

Proceedings of the National Academy of Sciences - PNAS, 1985-09, Vol.82 (17), p.5651-5655

1985

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β-Arrestin1 Modulates Lymphoid Enhancer Factor Transcriptional Activity through Interaction with Phosphorylated Dishevelled Proteins

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14889-14894

2001

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Chromosomal Organization of Adrenergic Receptor Genes

Proceedings of the National Academy of Sciences - PNAS, 1990-02, Vol.87 (4), p.1516-1520

1990

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Functional Antagonism of Different G Protein-Coupled Receptor Kinases for β-Arrestin-Mediated Angiotensin II Receptor Signaling

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (5), p.1442-1447

2005

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Monoclonal Antibodies Reveal Receptor Specificity among G-Protein-Coupled Receptor Kinases

Proceedings of the National Academy of Sciences - PNAS, 1996-07, Vol.93 (15), p.7649-7654

1996

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Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites

Molecular pharmacology, 1989-10, Vol.36 (4), p.641-646

1989

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Activity-Dependent Internalization of Smoothened Mediated by β-Arrestin 2 and GRK2

Science (American Association for the Advancement of Science), 2004-12, Vol.306 (5705), p.2257-2260

2004

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Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe

Molecular pharmacology, 1989-07, Vol.36 (1), p.15-22

1989

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β-Arrestin 2 Mediates Endocytosis of Type III TGF-β Receptor and Down-Regulation of Its Signaling

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1394-1397

2003

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Spinophilin Blocks Arrestin Actions In vitro and In vivo at G Protein-Coupled Receptors

Science (American Association for the Advancement of Science), 2004-06, Vol.304 (5679), p.1940-1944

2004

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ThemaBiochemistry & Molecular Biology

ThemaReceptors, Adrenergic, Beta - Metabolism

ThemaCell Line

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β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Hybrid Transgenic Mice Reveal In Vivo Specificity of G Protein–Coupled Receptor Kinases in the Heart

Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

Activation and Targeting of Extracellular Signal-Regulated Kinases by β-Arrestin Scaffolds

β-Arrestin 1 and 2 Differentially Regulate Heptahelical Receptor Signaling and Trafficking

Cloning and Expression of a Human Kidney cDNA for an α 2-adrenergic Receptor Subtype

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning

Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2

Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism

β-Arrestin1 Modulates Lymphoid Enhancer Factor Transcriptional Activity through Interaction with Phosphorylated Dishevelled Proteins

Chromosomal Organization of Adrenergic Receptor Genes

Functional Antagonism of Different G Protein-Coupled Receptor Kinases for β-Arrestin-Mediated Angiotensin II Receptor Signaling

Monoclonal Antibodies Reveal Receptor Specificity among G-Protein-Coupled Receptor Kinases

Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites

Activity-Dependent Internalization of Smoothened Mediated by β-Arrestin 2 and GRK2

Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe

β-Arrestin 2 Mediates Endocytosis of Type III TGF-β Receptor and Down-Regulation of Its Signaling

Spinophilin Blocks Arrestin Actions In vitro and In vivo at G Protein-Coupled Receptors

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