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Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?

Cell metabolism, 2015-03, Vol.21 (3), p.357-368

2015

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Detection of human adaptation during the past 2000 years

Science (American Association for the Advancement of Science), 2016-11, Vol.354 (6313), p.760-764

2016

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Early metabolic markers identify potential targets for the prevention of type 2 diabetes

Diabetologia, 2017-09, Vol.60 (9), p.1740-1750

2017

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Monogenic Diabetes in the Young, Pharmacogenetics and Relevance to Multifactorial Forms of Type 2 Diabetes

Endocrine reviews, 2008-05, Vol.29 (3), p.254-264

2008

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Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles

PloS one, 2017-06, Vol.12 (6), p.e0179583

2017

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Integration of clinical data with a genome‐scale metabolic model of the human adipocyte

Molecular systems biology, 2013, Vol.9 (1), p.649-n/a

2013

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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (1), p.287-298

2021

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Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene

PloS one, 2012-06, Vol.7 (6), p.e37423-e37423

2012

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DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

Diabetes (New York, N.Y.), 2016-10, Vol.65 (10), p.3062-3074

2016

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Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL

PloS one, 2016-09, Vol.11 (9), p.e0163046-e0163046

2016

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Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers

Nucleic acids research, 2012-09, Vol.40 (17), p.8255-8265

2012

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Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

American journal of human genetics, 2009-07, Vol.85 (1), p.106-111

2009

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Preadipocyte response and impairment of differentiation in an inflammatory environment

Biochemical and biophysical research communications, 2007-05, Vol.356 (3), p.662-667

2007

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Management of pregnancy in a patient with congenital hyperinsulinism treated with association of diazoxide/calcium channel blocker

Acta diabetologica, 2022-08, Vol.59 (8), p.1117-1120

2022

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Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children

Diabetologia, 2015-02, Vol.58 (2), p.290-294

2015

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Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates

International journal of molecular sciences, 2022-06, Vol.23 (13), p.7323

2022

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Predicting Diabetes: Clinical, Biological, and Genetic Approaches

Diabetes care, 2008-10, Vol.31 (10), p.2056-2061

2008

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Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

The Journal of biological chemistry, 2004-07, Vol.279 (29), p.30817-30822

2004

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Novel LEPR mutations in obese Pakistani children identified by PCR‐based enrichment and next generation sequencing

Obesity (Silver Spring, Md.), 2014-04, Vol.22 (4), p.1112-1117

2014

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Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice

PloS one, 2014-04, Vol.9 (4), p.e92684

2014

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Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation

The Journal of biological chemistry, 2002-07, Vol.277 (29), p.25863-25866

2002

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Interview: Philippe Froguel

European medical journal. Diabetes, 2024-10

Froguel, Philippe

2024

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RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

Cell biology international reports, 2014-12, Vol.9 (6), p.2206-2218

2014

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Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis

The Journal of biological chemistry, 2003-01, Vol.278 (4), p.2461-2468

2003

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Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

PLoS biology, 2003-10, Vol.1 (1), p.E20-E20

2003

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Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?

Detection of human adaptation during the past 2000 years

Early metabolic markers identify potential targets for the prevention of type 2 diabetes

Monogenic Diabetes in the Young, Pharmacogenetics and Relevance to Multifactorial Forms of Type 2 Diabetes

Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles

Integration of clinical data with a genome‐scale metabolic model of the human adipocyte

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL

Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

Preadipocyte response and impairment of differentiation in an inflammatory environment

Management of pregnancy in a patient with congenital hyperinsulinism treated with association of diazoxide/calcium channel blocker

Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children

Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates

Predicting Diabetes: Clinical, Biological, and Genetic Approaches

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

Novel LEPR mutations in obese Pakistani children identified by PCR‐based enrichment and next generation sequencing

Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice

Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation

Interview: Philippe Froguel

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

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