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1,2,3,4-Tetrahydroquinoline-Based Selective Human Neuronal Nitric Oxide Synthase (nNOS) Inhibitors: Lead Optimization Studies Resulting in the Identification of N-(1-(2-(Methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a Preclinical Development Candidate

Journal of medicinal chemistry, 2012-03, Vol.55 (6), p.2882-2893

2012

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1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (17), p.6374-6379

2009

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1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1793-1798

2007

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1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5368-5371

2008

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1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors

Chemistry & biodiversity, 2010-07, Vol.7 (7), p.1717-1727

2010

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1,2,3-Triazine scaffold as a potent biologically active moiety: a mini review

Mini reviews in medicinal chemistry, 2014-01, Vol.14 (1), p.72-83

2014

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1,2,3-Triazole-[2,5-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) (TSAO) Analogs: Synthesis and Anti-HIV-1 Activity

Journal of medicinal chemistry, 1994-11, Vol.37 (24), p.4185-4194

1994

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1,2,3-Triazole- and Quinoline-based Hybrids with Potent Antiplasmodial Activity

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2022-01, Vol.18 (5), p.521-535

2022

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1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

Bioorganic & medicinal chemistry, 2014-03, Vol.22 (5), p.1608-1619

2014

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1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors

Chembiochem : a European journal of chemical biology, 2005-07, Vol.6 (7), p.1167-1169

2005

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1,2,3‐Triazole‐based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition

Archiv der Pharmazie (Weinheim), 2024-03, Vol.357 (3), p.e2300372-n/a

2024

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1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

European journal of medicinal chemistry, 2019-12, Vol.183, p.111700-111700, Article 111700

2019

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1,2,3‐Triazole Derivatives as an Emerging Scaffold for Antifungal Drug Development against Candida albicans: A Comprehensive Review

Chemistry & biodiversity, 2023-05, Vol.20 (5), p.e202300024-n/a

2023

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1,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.308-313

2014

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1,2,3‐Triazole hybrids as anticancer agents: A review

Archiv der Pharmazie (Weinheim), 2022-01, Vol.355 (1), p.e2100158-n/a

Alam, Mohammad Mahboob

2022

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1,2,3‐Triazole hybrids with anti‐HIV‐1 activity

Archiv der Pharmazie (Weinheim), 2021-01, Vol.354 (1), p.e2000163-n/a

2021

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1,2,3-Triazole-nimesulide hybrid: Their design, synthesis and evaluation as potential anticancer agents

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (3), p.518-523

2017

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1,2,3-Triazole Stabilized Neurotensin-Based Radiopeptidomimetics for Improved Tumor Targeting

Bioconjugate chemistry, 2015-10, Vol.26 (10), p.2143-2152

2015

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1,2,3-triazole-substituted oleanolic Acid derivatives: synthesis and antiproliferative activity

Molecules (Basel, Switzerland), 2013-07, Vol.18 (7), p.7661-7674

2013

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1,2,3-Triazole tethered 1,2,4-trioxanes: Studies on their synthesis and effect on osteopontin expression in MDA-MB-435 breast cancer cells

European journal of medicinal chemistry, 2020-01, Vol.186, p.111908-111908, Article 111908

2020

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1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

Bioorganic chemistry, 2018-12, Vol.81, p.1-20

2018

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1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors

Bioorganic & medicinal chemistry, 2024-05, Vol.105, p.117727-117727, Article 117727

2024

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[1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors

European journal of medicinal chemistry, 2020-02, Vol.187, p.111989-111989, Article 111989

2020

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[1,2,3]Triazolo[4,5- h]quinolones. A new class of potent antitubercular agents against multidrug resistant Mycobacterium tuberculosis strains

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (17), p.4791-4794

2007

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1,2,4,5-Tetraoxacycloalkanes: synthesis and antimalarial activity

Mini reviews in medicinal chemistry, 2005-11, Vol.5 (11), p.1035-1043

2005

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1,2,3,4-Tetrahydroquinoline-Based Selective Human Neuronal Nitric Oxide Synthase (nNOS) Inhibitors: Lead Optimization Studies Resulting in the Identification of N-(1-(2-(Methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a Preclinical Development Candidate

1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation

1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors

1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors

1,2,3-Triazine scaffold as a potent biologically active moiety: a mini review

1,2,3-Triazole-[2,5-Bis-O-(tert-butyldimethylsilyl)-.beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) (TSAO) Analogs: Synthesis and Anti-HIV-1 Activity

1,2,3-Triazole- and Quinoline-based Hybrids with Potent Antiplasmodial Activity

1,2,3-Triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: Potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones

1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors

1,2,3‐Triazole‐based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition

1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

1,2,3‐Triazole Derivatives as an Emerging Scaffold for Antifungal Drug Development against Candida albicans: A Comprehensive Review

1,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin

1,2,3‐Triazole hybrids as anticancer agents: A review

1,2,3‐Triazole hybrids with anti‐HIV‐1 activity

1,2,3-Triazole-nimesulide hybrid: Their design, synthesis and evaluation as potential anticancer agents

1,2,3-Triazole Stabilized Neurotensin-Based Radiopeptidomimetics for Improved Tumor Targeting

1,2,3-triazole-substituted oleanolic Acid derivatives: synthesis and antiproliferative activity

1,2,3-Triazole tethered 1,2,4-trioxanes: Studies on their synthesis and effect on osteopontin expression in MDA-MB-435 breast cancer cells

1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors

[1,2,3]Triazolo[4,5-d]pyrimidine derivatives incorporating (thio)urea moiety as a novel scaffold for LSD1 inhibitors

[1,2,3]Triazolo[4,5- h]quinolones. A new class of potent antitubercular agents against multidrug resistant Mycobacterium tuberculosis strains

1,2,4,5-Tetraoxacycloalkanes: synthesis and antimalarial activity

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