UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8755-8774

2021

Volltextzugriff (PDF)

GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9045-9069

2020

Volltextzugriff (PDF)

Polypharmacology: challenges and opportunities in drug discovery

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.7874-7887

2014

Volltextzugriff (PDF)

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7310-7327

2015

Volltextzugriff (PDF)

Antiretroviral Activity of Thiosemicarbazone Metal Complexes

Journal of medicinal chemistry, 2010-12, Vol.53 (24), p.8765-8769

2010

Volltextzugriff (PDF)

The ProTide Prodrug Technology: From the Concept to the Clinic

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2211-2226

2018

Volltextzugriff (PDF)

Design, Synthesis, Biochemical, and Antiviral Evaluations of C6 Benzyl and C6 Biarylmethyl Substituted 2‑Hydroxylisoquinoline-1,3-diones: Dual Inhibition against HIV Reverse Transcriptase-Associated RNase H and Polymerase with Antiviral Activities

Journal of medicinal chemistry, 2015-01, Vol.58 (2), p.651-664

2015

Volltextzugriff (PDF)

Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12799-12813

2020

Volltextzugriff (PDF)

Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8042-8052

2021

Volltextzugriff (PDF)

Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy

Journal of medicinal chemistry, 2021-10, Vol.64 (19), p.14142-14152

2021

Volltextzugriff (PDF)

An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy

Journal of medicinal chemistry, 2016-07, Vol.59 (14), p.6595-6628

2016

Volltextzugriff (PDF)

Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2269-2300

2016

Volltextzugriff (PDF)

N‑O‑Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7224-7240

2015

Volltextzugriff (PDF)

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.699-726

2019

Volltextzugriff (PDF)

Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9601-9614

2015

Volltextzugriff (PDF)

Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.8186-8200

2024

Volltextzugriff (PDF)

Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.3306-3331

2022

Volltextzugriff (PDF)

Discovery of Novel Substituted N‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12830-12852

2020

Volltextzugriff (PDF)

A Review of Progress in Histone Deacetylase 6 Inhibitors Research: Structural Specificity and Functional Diversity

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1362-1391

2021

Volltextzugriff (PDF)

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.941-964

2019

Volltextzugriff (PDF)

Clearance in Drug Design

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2245

2019

Volltextzugriff (PDF)

Double-Winged 3‑Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV‑1 RNase H with Significant Antiviral Activity

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5045-5056

2017

Volltextzugriff (PDF)

Hydrocarbon-stapled peptides: principles, practice, and progress

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6275-6288

2014

Volltextzugriff (PDF)

Recent Progress in the Development of HIV‑1 Protease Inhibitors for the Treatment of HIV/AIDS

Journal of medicinal chemistry, 2016-06, Vol.59 (11), p.5172-5208

2016

Volltextzugriff (PDF)

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.7923-7956

2020

Volltextzugriff (PDF)

1 – 25 von 7.230

Suche als RSS-Feed

Aktive Filter

KollektionNature Journals Online

Zeitschrift / SerieJournal Of Medicinal Chemistry

ThemaChemistry, Medicinal

ThemaLife Sciences & Biomedicine

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(7.230)
Mit Volltextzugriff
(7.230)

Publikationsform

Artikel
(7.230)

Sprache

Englisch
(7.230)
Japanisch
(1.673)
Russisch
(7)
Norwegisch
(2)

Erscheinungsjahr

n.n

Thema

Pharmacology & Pharmacy
(7.230)
Science & Technology
(7.230)
Humans
(7.104)
Structure-Activity Relationship
(6.978)
Animals
(4.206)
Biological And Medical Sciences
(3.105)
Medical Sciences
(3.054)
Pharmacology. Drug Treatments
(3.008)
Models, Molecular
(2.305)
Mice
(2.120)
Rats
(1.662)
Antineoplastic Agents - Pharmacology
(1.625)
Molecular Structure
(1.599)
Cell Line, Tumor
(1.566)
Antineoplastic Agents - Chemical Synthesis
(1.493)
Antineoplastic Agents - Chemistry
(1.292)
Drug Screening Assays, Antitumor
(1.235)
Stereoisomerism
(1.220)

13 weitere anzeigen...

Weniger anzeigen...

Kollektion

MEDLINE
(7.225)
JSTOR
(1)
EZB Electronic Journals Library
(1)
Publisher
(1)
Springer Nature - Connect here FIRST to enable access
(0)

Zeitschrift / Serie

J. Med. Chem
(36)
J Med Chem
(7)
Korean Journal Of Medicinal Chemistry
(2)
J.Med.Chem.49:839,2006
(1)
Journal Of Medical Chemistry
(1)
Proceedings Of The National Academy Of Sciences - Pnas
(1)

1 weiteren anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein

GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins

Polypharmacology: challenges and opportunities in drug discovery

Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study

Antiretroviral Activity of Thiosemicarbazone Metal Complexes

The ProTide Prodrug Technology: From the Concept to the Clinic

Design, Synthesis, Biochemical, and Antiviral Evaluations of C6 Benzyl and C6 Biarylmethyl Substituted 2‑Hydroxylisoquinoline-1,3-diones: Dual Inhibition against HIV Reverse Transcriptase-Associated RNase H and Polymerase with Antiviral Activities

Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain

Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras

Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy

An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy

Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential

N‑O‑Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity

Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity

Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains

Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models

Discovery of Novel Substituted N‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors

A Review of Progress in Histone Deacetylase 6 Inhibitors Research: Structural Specificity and Functional Diversity

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Clearance in Drug Design

Double-Winged 3‑Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV‑1 RNase H with Significant Antiviral Activity

Hydrocarbon-stapled peptides: principles, practice, and progress

Recent Progress in the Development of HIV‑1 Protease Inhibitors for the Treatment of HIV/AIDS

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

Aktive Filter

Suchergebnisse filtern