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Synthesis, anticancer evaluation, and molecular docking studies of thiazolyl-pyrazoline derivatives

Bioorganic & medicinal chemistry letters, 2023-01, Vol.80, p.129105, Article 129105

2023

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Design and biological evaluation of a novel type of potential multi-targeting antimicrobial sulfanilamide hybrids in combination of pyrimidine and azoles

Bioorganic & medicinal chemistry letters, 2020-03, Vol.30 (6), p.126982-126982, Article 126982

2020

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Structure–activity relationship of 2-aminodibenzothiophene pharmacophore and the discovery of aminobenzothiophenes as potent inhibitors of Mycobacterium smegmatis

Bioorganic & medicinal chemistry letters, 2022-05, Vol.63, p.128650-128650, Article 128650

2022

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Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3732-3737

2013

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Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors

Bioorganic & medicinal chemistry letters, 2023-05, Vol.87, p.129266-129266, Article 129266

2023

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Cation exchange assisted binding-elution strategy for enzymatic synthesis of human milk oligosaccharides (HMOs)

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4285-4287

2017

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Design, synthesis and mechanistic studies of a TICT based fluorogenic probe for lighting up protein HSA

Bioorganic & medicinal chemistry letters, 2021-12, Vol.53, p.128438-128438, Article 128438

2021

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Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors

Bioorganic & medicinal chemistry letters, 2018-10, Vol.28 (18), p.3042-3045

2018

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Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease

Bioorganic & medicinal chemistry letters, 2024-11, Vol.112, p.129942, Article 129942

2024

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Ansamycin derivatives from the marine-derived Streptomyces sp. SCSGAA 0027 and their cytotoxic and antiviral activities

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127168-127168, Article 127168

2020

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Valproic acid induces three novel cytotoxic secondary metabolites in Diaporthe sp., an endophytic fungus from Datura inoxia Mill

Bioorganic & medicinal chemistry letters, 2018-07, Vol.28 (12), p.2217-2221

2018

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Synthesis and structure–activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (7), p.1762-1766

2016

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Novel selective proline-based peptidomimetics for human cathepsin K inhibition

Bioorganic & medicinal chemistry letters, 2024-09, Vol.110, p.129887, Article 129887

2024

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Revisiting the antiangiogenic mechanisms of fluorinated thalidomide derivatives

Bioorganic & medicinal chemistry letters, 2024-09, Vol.110, p.129858, Article 129858

2024

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Synthesis of chalcone derivatives as potential anti-diabetic agents

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.3912-3915

2012

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Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (7), p.1776-1783

2016

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Synthesis and biological evaluation of spiro[cyclopropane-1,3′-indolin]-2′-ones as potential anticancer agents

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4580-4586

2015

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Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5424-5427

2012

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Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (2), p.126816, Article 126816

2020

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Structure activity relationship of novel antiviral nucleosides against Enterovirus A71

Bioorganic & medicinal chemistry letters, 2020-12, Vol.30 (23), p.127599-127599, Article 127599

2020

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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (4), p.126896-126896, Article 126896

2020

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Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5438-5444

2012

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α-Pyrone derivatives with cytotoxic activities, from the endophytic fungus Phoma sp. YN02-P-3

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3723-3725

2017

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Recent applications of machine learning in medicinal chemistry

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2807-2815

2018

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Cathepsin B inhibitors: Further exploration of the nitroxoline core

Bioorganic & medicinal chemistry letters, 2018-04, Vol.28 (7), p.1239-1247

2018

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Synthesis, anticancer evaluation, and molecular docking studies of thiazolyl-pyrazoline derivatives

Design and biological evaluation of a novel type of potential multi-targeting antimicrobial sulfanilamide hybrids in combination of pyrimidine and azoles

Structure–activity relationship of 2-aminodibenzothiophene pharmacophore and the discovery of aminobenzothiophenes as potent inhibitors of Mycobacterium smegmatis

Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors

Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors

Cation exchange assisted binding-elution strategy for enzymatic synthesis of human milk oligosaccharides (HMOs)

Design, synthesis and mechanistic studies of a TICT based fluorogenic probe for lighting up protein HSA

Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors

Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease

Ansamycin derivatives from the marine-derived Streptomyces sp. SCSGAA 0027 and their cytotoxic and antiviral activities

Valproic acid induces three novel cytotoxic secondary metabolites in Diaporthe sp., an endophytic fungus from Datura inoxia Mill

Synthesis and structure–activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors

Novel selective proline-based peptidomimetics for human cathepsin K inhibition

Revisiting the antiangiogenic mechanisms of fluorinated thalidomide derivatives

Synthesis of chalcone derivatives as potential anti-diabetic agents

Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents

Synthesis and biological evaluation of spiro[cyclopropane-1,3′-indolin]-2′-ones as potential anticancer agents

Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents

Design, synthesis and biological evaluation of novel indole-based oxalamide and aminoacetamide derivatives as tubulin polymerization inhibitors

Structure activity relationship of novel antiviral nucleosides against Enterovirus A71

Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts

Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents

α-Pyrone derivatives with cytotoxic activities, from the endophytic fungus Phoma sp. YN02-P-3

Recent applications of machine learning in medicinal chemistry

Cathepsin B inhibitors: Further exploration of the nitroxoline core

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