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Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics

PLoS biology, 2018-12, Vol.16 (12), p.e2006265

2018

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The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

The Journal of clinical investigation, 2007-03, Vol.117 (3), p.648-658

2007

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SLC13A5 Deficiency Disorder: From Genetics to Gene Therapy

Genes, 2022-09, Vol.13 (9), p.1655

2022

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Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens

Orphanet journal of rare diseases, 2019-02, Vol.14 (1), p.27-27, Article 27

2019

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In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures

Molecular neurodegeneration, 2013-02, Vol.8 (1), p.9-9, Article 9

2013

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Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

Molecular neurodegeneration, 2014-01, Vol.9 (1), p.8-8, Article 8

2014

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Gene Transfer Therapy for Neurodevelopmental Disorders

Developmental neuroscience, 2021-09, Vol.43 (3-4), p.230-240

2021

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Identification of potential protein interactors of Lrrk2

Parkinsonism & related disorders, 2007-10, Vol.13 (7), p.382-385

2007

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Intrathecal Gene Therapy for Giant Axonal Neuropathy

The New England journal of medicine, 2024-03, Vol.390 (12), p.1092-1104

2024

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Extensive rod and cone photoreceptor-cell degeneration in rat models of giant axonal neuropathy: implications for gene therapy of human disease

Ophthalmic genetics, 2021-10, Vol.42 (5), p.600-603

2021

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LRRK2 phosphorylates novel tau epitopes and promotes tauopathy

Acta neuropathologica, 2013-12, Vol.126 (6), p.809-827

2013

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Methods for Gene Transfer to the Central Nervous System

Advances in Genetics, 2014, Vol.87, p.125-197

2014

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Autonomic nervous system involvement in the giant axonal neuropathy (GAN) KO mouse: implications for human disease

Clinical autonomic research, 2016-08, Vol.26 (4), p.307-313

2016

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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Cell, 2021-04, Vol.184 (7), p.1804-1820.e16

2021

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Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey

Annals of internal medicine, 2020-07, Vol.173 (2), p.100

2020

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Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

PloS one, 2018-10, Vol.13 (10), p.e0204513-e0204513

2018

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A qualitative study of facilitators and barriers to implementing worksite policies that support physical activity

BMC public health, 2018-09, Vol.18 (1), p.1145-8, Article 1145

2018

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Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania

BMC public health, 2011-05, Vol.11 (1), p.353-353, Article 353

2011

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Microtubule disruption reduces metastasis more effectively than primary tumor growth

Breast cancer research : BCR, 2022-02, Vol.24 (1), p.13-13, Article 13

2022

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A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial

The Lancet (British edition), 2021-01, Vol.397 (10270), p.208-219

2021

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Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation

PLoS genetics, 2014-10, Vol.10 (10), p.e1004758-e1004758

2014

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Risk factors for incident venous thromboembolism in active cancer patients: A population based case–control study

Thrombosis research, 2016-03, Vol.139, p.29-37

2016

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Knowledge and Behaviors of Adults with Underlying Health Conditions During the Onset of the COVID-19 U.S. Outbreak: The Chicago COVID-19 Comorbidities Survey

Journal of community health, 2020-12, Vol.45 (6), p.1149-1157

2020

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Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

SLC13A5 Deficiency Disorder: From Genetics to Gene Therapy

Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens

In vivo functional brain mapping in a conditional mouse model of human tauopathy (tauP301L) reveals reduced neural activity in memory formation structures

Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

Gene Transfer Therapy for Neurodevelopmental Disorders

Identification of potential protein interactors of Lrrk2

Intrathecal Gene Therapy for Giant Axonal Neuropathy

Extensive rod and cone photoreceptor-cell degeneration in rat models of giant axonal neuropathy: implications for gene therapy of human disease

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy

Methods for Gene Transfer to the Central Nervous System

Autonomic nervous system involvement in the giant axonal neuropathy (GAN) KO mouse: implications for human disease

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype

JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

A qualitative study of facilitators and barriers to implementing worksite policies that support physical activity

Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania

Microtubule disruption reduces metastasis more effectively than primary tumor growth

A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation

Risk factors for incident venous thromboembolism in active cancer patients: A population based case–control study

Knowledge and Behaviors of Adults with Underlying Health Conditions During the Onset of the COVID-19 U.S. Outbreak: The Chicago COVID-19 Comorbidities Survey

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