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1,2,4-Benzothiadiazine linked pyrrolo[2,1- c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (19), p.5345-5348

2007

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1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists

Journal of medicinal chemistry, 2007-10, Vol.50 (21), p.5076

2007

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[1,2,4]Triazolo[1,5‑a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12887-12910

2020

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1,2,4-Triazolyl azabicyclo[3.1.0]hexanes: a new series of potent and selective dopamine D(3) receptor antagonists

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.374-391

2010

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1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Journal of medicinal chemistry, 2002-06, Vol.45 (12), p.2362-2365

2002

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1.2-Anellated 1.4-Benzodiazepine Derivatives - A New Class of Antipsychotics

Pharmacopsychiatry, 1985-01, Vol.18 (1), p.174-177

1985

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1,25-Dihydroxyvitamin D to PTH(1-84) Ratios Strongly Predict Cardiovascular Death in Heart Failure

PloS one, 2015-08, Vol.10 (8), p.e0135427

2015

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1,25-dihydroxyvitamin D3 induces LL-37 and HBD-2 production in keratinocytes from diabetic foot ulcers promoting wound healing: an in vitro model

PloS one, 2014-10, Vol.9 (10), p.e111355

2014

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1,25(OH) 2 D 3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis

Biomedicine & pharmacotherapy, 2020-08, Vol.128, p.110256

2020

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1-[3-(Diarylamino)propyl]piperidines and Related Compounds, Potential Antipsychotic Agents with Low Cataleptogenic Profiles

Journal of medicinal chemistry, 1985-05, Vol.28 (5), p.606-612

1985

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1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists

Journal of medicinal chemistry, 2003-04, Vol.46 (8), p.1504-1511

2003

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1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors

ChemMedChem, 2009-03, Vol.4 (3), p.393

2009

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1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.3740-3751

2010

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1,3-Disubstituted-2-carboxy quinolones: highly potent and selective endothelin A receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-07, Vol.10 (13), p.1487-1490

2000

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1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Journal of medicinal chemistry, 2003-06, Vol.46 (13), p.2774-2789

2003

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(1→3)-β-d-Glucan reduces the damages caused by reactive oxygen species induced in human platelets by lipopolysaccharides

Carbohydrate polymers, 2013-09, Vol.97 (2), p.716-724

2013

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1-(4-Amino-phenyl)-pyrrolidin-3-yl-amine and 6-(3-amino-pyrrolidin-1-yl)-pyridin-3-yl-amine derivatives as melanin-concentrating hormone receptor-1 antagonists

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (16), p.3701-3706

2005

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1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C‑2 and C‑6 Positions

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4718-4728

2013

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1,4‐Dihydropyridinebutyrolactone‐derived ring‐opened ester and amide analogs targeting BET bromodomains

Archiv der Pharmazie (Weinheim), 2022-11, Vol.355 (11), p.e2200288-n/a

2022

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1,4-Dihydropyridines versus beta-blockers for hypertension : Are either safe for the heart ?

Cardiovascular drugs and therapy, 1996-09, Vol.10 (4), p.397-402

LEENEN, F. H. H

1996

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1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma

European journal of medicinal chemistry, 2017-11, Vol.140, p.84-91

2017

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1,6-Dihydro-2H-indeno[5,4-b]furan Derivatives: Design, Synthesis, and Pharmacological Characterization of a Novel Class of Highly Potent MT2-Selective Agonists

Journal of medicinal chemistry, 2011-05, Vol.54 (9), p.3436-3444

2011

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1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase

Journal of medicinal chemistry, 2011-11, Vol.54 (22), p.7899-7910

2011

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1-Amino-substituted 4-methyl-5H-pyrido[4,3-b]indoles (.gamma.-carbolines) as tricyclic analogs of ellipticines: a new class of antineoplastic agents

Journal of medicinal chemistry, 1988-02, Vol.31 (2), p.398-405

1988

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