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Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY

The Journal of biological chemistry, 2016-12, Vol.291 (53), p.27023-27041

2016

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A Structural Snapshot of Type II Pilus Formation in Streptococcus pneumoniae

The Journal of biological chemistry, 2015-09, Vol.290 (37), p.22581-22592

2015

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Structural Biology of Presenilins and Signal Peptide Peptidases

The Journal of biological chemistry, 2013-05, Vol.288 (21), p.14673-14680

2013

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Structure-Function Similarities between a Plant Receptor-like Kinase and the Human Interleukin-1 Receptor-associated Kinase-4

The Journal of biological chemistry, 2011-04, Vol.286 (13), p.11202-11210

2011

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The N-terminal Region of the DNA-dependent Protein Kinase Catalytic Subunit Is Required for Its DNA Double-stranded Break-mediated Activation

The Journal of biological chemistry, 2013-03, Vol.288 (10), p.7037-7046

2013

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Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.3682-3692

2016

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Activation of p115-RhoGEF Requires Direct Association of Gα13 and the Dbl Homology Domain

The Journal of biological chemistry, 2012-07, Vol.287 (30), p.25490-25500

2012

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Significant Impact of Single N-Glycan Residues on the Biological Activity of Fc-based Antibody-like Fragments

The Journal of biological chemistry, 2012-07, Vol.287 (29), p.24313-24319

2012

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Quaternary Structure Controls Ligand Dynamics in Soluble Guanylate Cyclase

The Journal of biological chemistry, 2012-02, Vol.287 (9), p.6851-6859

2012

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Erythrocytic Stage-dependent Regulation of Oligomerization of Plasmodium Ribosomal Protein P2

The Journal of biological chemistry, 2012-11, Vol.287 (49), p.41499-41513

2012

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Huntingtin-associated Protein-1 Deficiency in Orexin-producing Neurons Impairs Neuronal Process Extension and Leads to Abnormal Behavior in Mice

The Journal of biological chemistry, 2010-05, Vol.285 (21), p.15941-15949

2010

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Streptococcal Surface Proteins Activate the Contact System and Control Its Antibacterial Activity

The Journal of biological chemistry, 2012-07, Vol.287 (30), p.25010-25018

2012

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Assembly of a Filamin Four-domain Fragment and the Influence of Splicing Variant-1 on the Structure

The Journal of biological chemistry, 2011-07, Vol.286 (30), p.26921-26930

2011

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Functional Differences of Invariant and Highly Conserved Residues in the Extracellular Domain of the Glycoprotein Hormone Receptors

The Journal of biological chemistry, 2010-11, Vol.285 (45), p.34813-34827

2010

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Structure-Function Studies of the SLC17 Transporter Sialin Identify Crucial Residues and Substrate-induced Conformational Changes

The Journal of biological chemistry, 2010-06, Vol.285 (25), p.19316-19323

2010

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Cellular and Biochemical Impact of a Mutation in DNA Ligase IV Conferring Clinical Radiosensitivity

The Journal of biological chemistry, 2001-08, Vol.276 (33), p.31124-31132

2001

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Structural Requirements for Additional N-Linked Carbohydrate on Recombinant Human Erythropoietin

The Journal of biological chemistry, 2004-04, Vol.279 (16), p.16854-16862

2004

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Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites

The Journal of biological chemistry, 2005-06, Vol.280 (24), p.22962-22967

2005

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Essential Roles of Zinc Ligation and Enzyme Dimerization for Catalysis in the Aminoacylase-1/M20 Family

The Journal of biological chemistry, 2003-11, Vol.278 (45), p.44496-44504

2003

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Structural Determination of Lipid-bound ApoA-I Using Fluorescence Resonance Energy Transfer

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.37048-37054

2000

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Characterization of Structural Domains of Human Osteoclastogenesis Inhibitory Factor

The Journal of biological chemistry, 1998-02, Vol.273 (9), p.5117-5123

1998

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Voltage Gating at the Selectivity Filter of the Ca2+ Release-activated Ca2+ Channel Induced by Mutation of the Orai1 Protein

The Journal of biological chemistry, 2008-05, Vol.283 (22), p.14938-14945

2008

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Structure of the Mature Ectodomain of the Human Receptor-type Protein-tyrosine Phosphatase IA-2

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.4674-4681

2008

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Structure and Function of the c-myc DNA-unwinding Element-binding Protein DUE-B

The Journal of biological chemistry, 2007-04, Vol.282 (14), p.10441-10448

2007

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Cell Surface Expression of the Melanocortin-4 Receptor Is Dependent on a C-terminal Di-isoleucine Sequence at Codons 316/317

The Journal of biological chemistry, 2003-05, Vol.278 (18), p.15935-15940

2003

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Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY

A Structural Snapshot of Type II Pilus Formation in Streptococcus pneumoniae

Structural Biology of Presenilins and Signal Peptide Peptidases

Structure-Function Similarities between a Plant Receptor-like Kinase and the Human Interleukin-1 Receptor-associated Kinase-4

The N-terminal Region of the DNA-dependent Protein Kinase Catalytic Subunit Is Required for Its DNA Double-stranded Break-mediated Activation

Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling

Activation of p115-RhoGEF Requires Direct Association of Gα13 and the Dbl Homology Domain

Significant Impact of Single N-Glycan Residues on the Biological Activity of Fc-based Antibody-like Fragments

Quaternary Structure Controls Ligand Dynamics in Soluble Guanylate Cyclase

Erythrocytic Stage-dependent Regulation of Oligomerization of Plasmodium Ribosomal Protein P2

Huntingtin-associated Protein-1 Deficiency in Orexin-producing Neurons Impairs Neuronal Process Extension and Leads to Abnormal Behavior in Mice

Streptococcal Surface Proteins Activate the Contact System and Control Its Antibacterial Activity

Assembly of a Filamin Four-domain Fragment and the Influence of Splicing Variant-1 on the Structure

Functional Differences of Invariant and Highly Conserved Residues in the Extracellular Domain of the Glycoprotein Hormone Receptors

Structure-Function Studies of the SLC17 Transporter Sialin Identify Crucial Residues and Substrate-induced Conformational Changes

Cellular and Biochemical Impact of a Mutation in DNA Ligase IV Conferring Clinical Radiosensitivity

Structural Requirements for Additional N-Linked Carbohydrate on Recombinant Human Erythropoietin

Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites

Essential Roles of Zinc Ligation and Enzyme Dimerization for Catalysis in the Aminoacylase-1/M20 Family

Structural Determination of Lipid-bound ApoA-I Using Fluorescence Resonance Energy Transfer

Characterization of Structural Domains of Human Osteoclastogenesis Inhibitory Factor

Voltage Gating at the Selectivity Filter of the Ca2+ Release-activated Ca2+ Channel Induced by Mutation of the Orai1 Protein

Structure of the Mature Ectodomain of the Human Receptor-type Protein-tyrosine Phosphatase IA-2

Structure and Function of the c-myc DNA-unwinding Element-binding Protein DUE-B

Cell Surface Expression of the Melanocortin-4 Receptor Is Dependent on a C-terminal Di-isoleucine Sequence at Codons 316/317

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