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A Perspective on the Kinetics of Covalent and Irreversible Inhibition

SLAS discovery, 2017-01, Vol.22 (1), p.3-20

Strelow, John M

2017

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Benzotriazoles and Indazoles Are Scaffolds with Biological Activity against Entamoeba histolytica

Journal of biomolecular screening, 2011-09, Vol.16 (8), p.862-868

2011

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Ligand Detection in the Allosteric World

Journal of biomolecular screening, 2010-02, Vol.15 (2), p.119-130

Kenakin, Terry P.

2010

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Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles

Journal of biomolecular screening, 2014-06, Vol.19 (5), p.738-748

2014

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An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification

Journal of biomolecular screening, 2016-09, Vol.21 (8), p.832-841

2016

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High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

Journal of biomolecular screening, 2013-09, Vol.18 (8), p.910-920

2013

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Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1072-1083

2013

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High-Throughput Screening Using a Whole-Cell Virus Replication Reporter Gene Assay to Identify Inhibitory Compounds against Rift Valley Fever Virus Infection

Journal of biomolecular screening, 2016-04, Vol.21 (4), p.354-362

2016

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Identification of potent VHZ phosphatase inhibitors with structure-based virtual screening

Journal of biomolecular screening, 2013-02, Vol.18 (2), p.226-231

2013

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The BlueScreen-384 assay as an indicator of genotoxic hazard potential in early-stage drug discovery

Journal of biomolecular screening, 2013-04, Vol.18 (4), p.441-452

2013

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Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF)

Journal of biomolecular screening, 2016-06, Vol.21 (5), p.446-458

2016

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Quantification of histone H3 Lys27 trimethylation (H3K27me3) by high-throughput microscopy enables cellular large-scale screening for small-molecule EZH2 inhibitors

Journal of biomolecular screening, 2015-02, Vol.20 (2), p.190-201

2015

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Mining Natural-Products Screening Data for Target-Class Chemical Motifs

Journal of biomolecular screening, 2014-06, Vol.19 (5), p.749-757

2014

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The Use of Nucleosome Substrates Improves Binding of SAM Analogs to SETD8

Journal of biomolecular screening, 2016-09, Vol.21 (8), p.786-794

2016

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Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni

Journal of biomolecular screening, 2015-01, Vol.20 (1), p.112-121

2015

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A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry

Journal of biomolecular screening, 2013-01, Vol.18 (1), p.26-38

2013

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A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1110-1120

2013

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Fe(III)-salen and salphen complexes induce caspase activation and apoptosis in human cells

Journal of biomolecular screening, 2011-01, Vol.16 (1), p.26-35

2011

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Development of a Medium-Throughput Targeted LCMS Assay to Detect Endogenous Cellular Levels of Malonyl-CoA to Screen Fatty Acid Synthase Inhibitors

Journal of biomolecular screening, 2016-02, Vol.21 (2), p.111-116

2016

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High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase

Journal of biomolecular screening, 2012-07, Vol.17 (6), p.738-751

2012

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Use of cryopreserved cells for enabling greater flexibility in compound profiling

Journal of biomolecular screening, 2008-06, Vol.13 (5), p.354-362

2008

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Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1092-1102

2013

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A Set of Time-Resolved Fluorescence Resonance Energy Transfer Assays for the Discovery of Inhibitors of Estrogen Receptor-Coactivator Binding

Journal of biomolecular screening, 2009-02, Vol.14 (2), p.181-193

2009

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Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

Journal of biomolecular screening, 2010-07, Vol.15 (6), p.663-670

2010

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Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1043-1053

2013

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A Perspective on the Kinetics of Covalent and Irreversible Inhibition

Benzotriazoles and Indazoles Are Scaffolds with Biological Activity against Entamoeba histolytica

Ligand Detection in the Allosteric World

Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles

An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification

High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1

Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research

High-Throughput Screening Using a Whole-Cell Virus Replication Reporter Gene Assay to Identify Inhibitory Compounds against Rift Valley Fever Virus Infection

Identification of potent VHZ phosphatase inhibitors with structure-based virtual screening

The BlueScreen-384 assay as an indicator of genotoxic hazard potential in early-stage drug discovery

Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF)

Quantification of histone H3 Lys27 trimethylation (H3K27me3) by high-throughput microscopy enables cellular large-scale screening for small-molecule EZH2 inhibitors

Mining Natural-Products Screening Data for Target-Class Chemical Motifs

The Use of Nucleosome Substrates Improves Binding of SAM Analogs to SETD8

Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni

A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry

A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes

Fe(III)-salen and salphen complexes induce caspase activation and apoptosis in human cells

Development of a Medium-Throughput Targeted LCMS Assay to Detect Endogenous Cellular Levels of Malonyl-CoA to Screen Fatty Acid Synthase Inhibitors

High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase

Use of cryopreserved cells for enabling greater flexibility in compound profiling

Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1

A Set of Time-Resolved Fluorescence Resonance Energy Transfer Assays for the Discovery of Inhibitors of Estrogen Receptor-Coactivator Binding

Phenothiazine Neuroleptics Signal to the Human Insulin Promoter as Revealed by a Novel High-Throughput Screen

Establishing a high-throughput and automated cancer cell proliferation panel for oncology lead optimization

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