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Pyroptotic cell death defends against intracellular pathogens

Immunological reviews, 2015-05, Vol.265 (1), p.130-142

2015

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An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages

Cell reports (Cambridge), 2020-07, Vol.32 (4), p.107959-107959, Article 107959

2020

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FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes

The Journal of immunology (1950), 2014-02, Vol.192 (4), p.1835-1846

2014

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The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Cell reports (Cambridge), 2018-11, Vol.25 (9), p.2339-2353.e4

2018

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Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis

Cold Spring Harbor perspectives in biology, 2020-05, Vol.12 (5), p.a036392

2020

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Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages

Cell chemical biology, 2017-04, Vol.24 (4), p.507-514.e4

2017

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An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

Science (American Association for the Advancement of Science), 2020-02, Vol.367 (6478), p.652-660

2020

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Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium

Cell host & microbe, 2015-09, Vol.18 (3), p.320-332

2015

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Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

Immunity (Cambridge, Mass.), 2009-07, Vol.31 (1), p.84-98

2009

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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

Cell reports (Cambridge), 2020-07, Vol.32 (4), p.107967-107967, Article 107967

2020

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Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models

Food & function, 2018-11, Vol.9 (11), p.5682-5696

2018

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Executioner caspase-3 and caspase-7 are functionally distinct proteases

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.12815-12819

2008

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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6417), p.956-960

2018

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Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injury

Neuroreport, 2021-02, Vol.32 (3), p.188

2021

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Bacterial recognition pathways that lead to inflammasome activation

Immunological reviews, 2015-05, Vol.265 (1), p.112-129

2015

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Live-cell visualization of gasdermin D-driven pyroptotic cell death

The Journal of biological chemistry, 2017-09, Vol.292 (35), p.14649-14658

2017

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Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients

Hepatology (Baltimore, Md.), 2018-05, Vol.67 (5), p.1737-1753

2018

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The role of caspase-8 in inflammatory signalling and pyroptotic cell death

Seminars in immunology, 2023-11, Vol.70, p.101832-101832, Article 101832

2023

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Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

Cell metabolism, 2013-10, Vol.18 (4), p.519-532

2013

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Caspase-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apoptosis Pathway in Auditory Cells

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5896

2019

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Role of Mitochondria and Endoplasmic Reticulum in Taurine-Deficiency-Mediated Apoptosis

Nutrients, 2017-07, Vol.9 (8), p.795

2017

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Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice

Journal of agricultural and food chemistry, 2017-10, Vol.65 (42), p.9226-9236

2017

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Burn-Induced Apoptosis in the Livers of Aged Mice Is Associated With Caspase Cleavage of Bcl-xL

The Journal of surgical research, 2023-10, Vol.290, p.147-155

2023

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Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1

The Journal of biological chemistry, 2018-05, Vol.293 (18), p.7058-7067

2018

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The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

Neurobiology of disease, 2016-02, Vol.86, p.29-40

2016

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Pyroptotic cell death defends against intracellular pathogens

An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis

Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages

An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models

Executioner caspase-3 and caspase-7 are functionally distinct proteases

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injury

Bacterial recognition pathways that lead to inflammasome activation

Live-cell visualization of gasdermin D-driven pyroptotic cell death

Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients

The role of caspase-8 in inflammatory signalling and pyroptotic cell death

Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

Caspase-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apoptosis Pathway in Auditory Cells

Role of Mitochondria and Endoplasmic Reticulum in Taurine-Deficiency-Mediated Apoptosis

Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice

Burn-Induced Apoptosis in the Livers of Aged Mice Is Associated With Caspase Cleavage of Bcl-xL

Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1

The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

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